Protein Overview: PRM2

General Information:
Name(s) found:	PRM2 / YIL037C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731798\|sp\|P40534.1\|PRM2_YEAST RecName: Full=Pheromone-regulated membrane protein 3 [NCBI NR] gi\|6322152\|ref\|NP_012227.1\| Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; Prm2p [Saccharomyces cerevisiae] [NCBI NR] gi\|600011\|emb\|CAA86914.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S49941 probable membrane protein YIL037c - yeast (Saccharomyces cerevisiae) [NCBI NR] (P40534) Hypothetical 75.0 kDa protein in NOT3-CKA1 intergenic region [Swiss-Prot] Pheromone-regulated membrane protein 3 OS=Saccharomyces cerevisiae GN=PRM2 PE=1 SV=1 [Swiss-Prot] PRM2 Pheromone-regulated protein via Ste12p [mips] Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion [SGD] PRM2, Chr IX from 283028-284998, reverse complement [yeast_orfs2] Chr IX from 283028-284998, reverse complement [yeastorf3.fasta] Chr IX from 284998-283028, reverse complement [yeastorf5.fasta] PRM2 SGDID:S0001299, Chr IX from 284998-283028, reverse complement, Verified ORF [yeastflysequest.fasta] Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p [Saccharomyces cerevisiae]gi\|600011\|emb\|CAA86914.1\| unknown [Saccharomyces cerevisiae]gi\|731798\|sp\|P40534\|YID7_YEAST Hypothetical 75.0 [nrdb_11152004_Chlamydomonas] PRM2 SGDID:S000001299, Chr IX from 284998-283028, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; Prm2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Hypothetical 75.0 kDa protein in NOT3-CKA1 intergenic region [nr-271106-contam.fasta] PRM2 SGDID:S000001299, Chr IX from 284998-283028, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] Pheromone-regulated membrane protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRM2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] PRM2 SGDID:S000001299, Chr IX from 284999-283029, Genome Release 64-1-1, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion" [yeast-030211-contam.fasta] Pheromone-regulated membrane protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRM2 PE=2 SV=1 [YEAST.fasta.20131015] PRM2 SGDID:S000001299, Chr IX from 284999-283029, Genome Release 64-2-1, reverse complement, Verified ORF, "Pheromone-regulated protein; predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion" [20141208_orf_trans.fasta] YIL037C SGDID:S000001299, Chr IX from 284999-283029, Genome Release 64-1-1, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] Pheromone-regulated membrane protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRM2 PE=2 SV=1 [Swanson-Carlisle-Scereplusabalone-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	656 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	conjugation with cellular fusion [IEP] response to pheromone [IEP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNVHIIKPL SLPQRFFSCI FHPLLLIFFT SVILTIWGSF SVIDITMAKM SHAQVKRNDT  60
   61 VSTFASISTA TATATTTATT TATMTAVTTQ HAIYSANSYS LNKTFIDNTI DQYFESKLRS 120
  121 IESTVGTDMQ EKFKSYTDDI LDNKQKLIND QISLETELIK EVLEVNNTIF NELLTKSQLI 180
  181 NDTWNEISED AMTIDKDSIS QMASNLLLNY SMFDSIFGNY SRKLKSLQNF NGTITDFSTQ 240
  241 LDTSSTLSLN FLRNSTDWLQ LKRNFTANLQ NEISILSGGS TEVTSSTSII KRSLKTNSEE 300
  301 NSVLSAVKNH VFRKCKRMTI IFTVMYFAFV ILLMAIERIL FQLENQQVNL VMSQINGLTG 360
  361 QTNFTKYNKV LKSLITTLNL STLYPIPYQL TKLINQKIFK REPEKIDDKK VKKSKLFYCN 420
  421 WWIISNGAHL WLFGFLMLLI HWQIVTRLTN FEVPSLPTFH KRAGPSLYKR EVWTDGNITT 480
  481 TIEGFINDSV SLLCENFQME VNEKFITANL SLQTDPNLKV QSTDILNLWV NDTNTQFEKY 540
  541 LNESSQNWQG IDLQVEPLLG SDSINEFLGQ YFLPTYEVTN TNSSFALDIQ KYGIINRGIN 600
  601 ITNASVAALS SLSKRQIKDK EQKQTYFLHT VYKWGLLAVC LTILFHHMLI FIILKL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		AAT2 ACH1 ACO1 AFR1 AHP1 ARC1 ARF1 ATP3 CAR2 CDC33 CLU1 COF1 COR1 CPR1 CYR1 CYS4 EGD1 ERG13 ERG6 FPR1 FRS2 GND1 GND2 GRX1 GUS1 HEF3 HHF1, HHF2 LRO1 LSP1 MET6 NTF2 OLA1 OYE2 PFK1 PIL1 PRM2 RNR2 RSN1 SAH1 SCP160 SEC53 SEN15 SES1 SNU13 SOD1 TEF4 THS1 TIF1, TIF2 TMA19 TSA2 UBA1 VMA4 VMA5 WTM1 YNK1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NUC1	PRM2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PRM2	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..99]	deduced	N/A	No confident structure predictions are available.
2	View Details	[100..580]	ab initio	7.31	No description for 1l9uD was found.
3	View Details	[581..656]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2