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Protein Overview: YSP1

General Information:
Name(s) found: YSP1 / YHR155W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1228 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHEHKAELRL ITVALNEAST DSPSFRASVN YFHTRMESLS SWMHSTVDYV ENTYKPSFQD  60
   61 FQRIKETLFS QLLPSPILLS NGFVSNQPYT PLLVRDFTRD VSDLSNTVMK IILGDENSQY 120
  121 TAALSALSSD AINPYFNKRK TFEYYQRKYD SFLTDFLAAT NDGNTLIPQN LQNETFKLVD 180
  181 IKHKYIEASL DLTEAISLMK VNLDKFLIET IDIVRKNNVI TTKDTKDVID ITPELTETLK 240
  241 DWTDWIESNL QTLQALSSKL SEAKYAILKL SLARMKPSRL IQDYDLKSIQ NLKFNLPKSI 300
  301 SNGNNSEEKG LSGWLYMKTT VGHDPKRVVW VRRWCFLQNN VFGVFSLSPS KTYVEETDKF 360
  361 GILWITVEYL PKEPRNFCFK LRIQNPNCKT EEENTYIDII LQAESIDELK SWINTLTSHK 420
  421 RIALSIKEEN DPRYQLARKK IEPQFFEFAS SSSTSTDKLL TSFSSKTLTL VEELKKNYMS 480
  481 EDDIYSIIDN KAYHLRVIST PIATQLTHLA LFSTFLSVSN YYPCATQANT WGTANWNDLS 540
  541 YLVNPLKGSS VHKPATVSNS SRFSVSYPDY YPYSLKVDDI QFRSIFFSVN HDFLQVPKEL 600
  601 VLLRYSSVWC PNNKQKFASM AFVTLNHIYV YLNISGFSYL RRIDLLDIDS IEYDKSPKHV 660
  661 SSRMLHMQRG DGLRFNMSVF FTDRRAVASK LQFLIENKAM HIPKGEKEVL EIFQELDEEI 720
  721 ENEKKIIKDN LSESEHYSKD YDYLLKSTYD HHFENTNETP MELMSRKLRL EREAWCYFQD 780
  781 NFKVGSKTLF HVLFGDKSQV FPSSLFLCKK GSNLNNNSYW ERIRRAKEDA SCQFELCRKL 840
  841 QFQLNRTSNF IKDLLWLKDD NDNFKLVLQQ RVTKIKQGYY FEVEEGPIIV KFPLCHPLLL 900
  901 RVRFIIAECI TSQGESLKKC DLAILYDFNY VESIDKLNTK VEKLWLFERI HLNWALRYCK 960
  961 LEHSEINRKT REYLKKFNDR EKMSDVIKLC GFLGVLPKER IENDEKAGDF MQPVYINYDF1020
 1021 LSLSKIFTKL TVFYLSSVII KTMKVLLAMV MVIFKCFSKV NKTLYYCLLI SAVTNLFFVG1080
 1081 KSIHSYFSVK SAETLFQNYA NGDQRGLQIM HRSLTVPDLN LLTRKMMDND QENPVFKRFD1140
 1141 EDKNAYQYKG TRQEIAIKRN QVLTELKILQ NTEKELVQGS YRKFIITERD KCITTQNEIF1200
 1201 DLWINDTKLQ DYCMACFAEY NRLSAIPV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CHL4 No Comments Cheeseman IM, et al. (2002)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC23 YSP1 1 Unpublished Fields Lab Data
    View Screen CDC53 YSP1 1 Unpublished Fields Lab Data
    View Screen RAD51 YSP1 1 Unpublished Fields Lab Data
    View Screen DMC1 YSP1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YSP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] MSA 4.06599 View MSA. No confident structure predictions are available.
    2 View Details [114..189] PSI-BLAST 14.0 Exchange factor ARNO
    3 View Details [190..296] PSI-BLAST 14.0 Exchange factor ARNO
    4 View Details [297..467] PSI-BLAST 18.0 Tapp1
    5 View Details [468..571] PSI-BLAST 2.39794 Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
    6 View Details [572..1228] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  3.17213698546013 bayes_pls_golite062009
  • binding
    		•  2.86147407357315 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.50756932992573 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.2749362891779 bayes_pls_golite062009
  • DNA binding
    		•  1.18878662922624 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.236765394237244 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.198922924806251 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.95502209146398 bayes_pls_golite062009
  • DNA binding
    		•  4.49877554292304 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.4138116788102 bayes_pls_golite062009
  • transcription factor activity
    		•  3.78905634607011 bayes_pls_golite062009
  • transcription activator activity
    		•  3.19708783401986 bayes_pls_golite062009
  • binding
    		•  3.09940998297931 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.07549097279613 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.10135825467854 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.72704408652215 bayes_pls_golite062009
  • transcription factor binding
    		•  0.35726633913804 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.18158516638045 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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