Protein Overview: SNF6

General Information:
Name(s) found:	SNF6 / YHL025W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6321762\|ref\|NP_011838.1\| Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; Snf6p [Saccharomyces cerevisiae] [NCBI NR] gi\|2289895\|gb\|AAB65078.1\| Probable transcription factor [Saccharomyces cerevisiae] [NCBI NR] gi\|172642\|gb\|AAA35064.1\| nuclear protein SNF6 [NCBI NR] gi\|172640\|gb\|AAA35063.1\| SNF6 protein [Saccharomyces cerevisiae] [NCBI NR] gi\|134592\|sp\|P18888.1\|SNF6_YEAST RecName: Full=Transcription regulatory protein SNF6; AltName: Full=SWI/SNF complex component SNF6 [NCBI NR] pir\|\|A36313 sucrose nonfermenting protein 6 - yeast (Saccharomyces cerevisiae) [NCBI NR] Transcription regulatory protein SNF6 OS=Saccharomyces cerevisiae GN=SNF6 PE=1 SV=1 [Swiss-Prot] SNF6 Global transcription activator [mips] Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p [SGD] SNF6, Chr VIII from 54848-55846 [yeast_orfs2] Chr VIII from 54848-55846 [yeastorf3.fasta] (P18888) Transcription regulatory protein SNF6 (SWI/SNF complex component SNF6) [4932.FASTACCERV.txt] SNF6 SGDID:S0001017, Chr VIII from 54848-55846, Verified ORF [yeastflysequest.fasta] Involved in global regulation of transcription; subunit of the chromatin remodeling Snf/Swi complex [Saccharomyces cerevisiae]gi\|2289895\|gb\|AAB65078.1\| Probable transcription factor [Saccharomyces cerevisiae]gi\|134592\|sp\|P18888\|SNF6_YEAST Transcription [nrdb_11152004_Chlamydomonas] SNF6 SGDID:S000001017, Chr VIII from 54849-55847, Verified ORF, "One of 11 subunits of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SNF6 SGDID:S000001017, Chr VIII from 54849-55847, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p" [yeast-contam.fasta] Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; Snf6p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Transcription regulatory protein SNF6 (SWI/SNF complex component SNF6) [nr-271106-contam.fasta] SNF6 protein [nr-271106-contam.fasta] Probable transcription factor [Saccharomyces cerevisiae] [nr-271106-contam.fasta] nuclear protein SNF6 [nr-271106-contam.fasta] [chemostatdb.fasta] Transcription regulatory protein SNF6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNF6 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SNF6 SGDID:S000001017, Chr VIII from 54851-55849, Genome Release 64-1-1, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p" [yeast-030211-contam.fasta] SNF6 SGDID:S000001017, Chr VIII from 54851-55849, Genome Release 64-2-1, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; relocates to the cytosol under hypoxic conditions" [20141208_orf_trans.fasta] TR8587\|c0_g1_i1\|g.5961 ORF TR8587\|c0_g1_i1\|g.5961 TR8587\|c0_g1_i1\|m.5961 type:complete len:333 (+) TR8587\|c0_g1_i1:861-1859(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR2416\|c0_g1_i1\|g.1696 ORF TR2416\|c0_g1_i1\|g.1696 TR2416\|c0_g1_i1\|m.1696 type:complete len:333 (+) TR2416\|c0_g1_i1:1013-2011(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YHL025W SGDID:S000001017, Chr VIII from 54851-55849, Genome Release 64-1-1, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_7913\|g.5938 ORF asmbl_7913\|g.5938 asmbl_7913\|m.5938 type:complete len:333 (+) asmbl_7913:937-1935(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_8117\|g.4900 ORF ID=asmbl_8117\|g.4900 ID=asmbl_8117\|m.4900 type:complete len:333 (+) ID=asmbl_8117:937-1935(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_8293\|g.5059 ORF ID=asmbl_8293\|g.5059 ID=asmbl_8293\|m.5059 type:complete len:333 (+) ID=asmbl_8293:1045-2043(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	332 amino acids
Gene Ontology:
Cellular Component:	SWI/SNF complex [TAS] chromatin remodeling complex [TAS]
Biological Process:	chromatin remodeling [TAS]
Molecular Function:	general RNA polymerase II transcription factor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVIKKKRSH HGKASRQQYY SGVQVGGVGS MGAINNNIPS LTSFAEENNY QYGYSGSSAG  60
   61 MNGRSLTYAQ QQLNKQRQDF ERVRLRPEQL SNIIHDESDT ISFRSNLLKN FISSNDAFNM 120
  121 LSLTTVPCDR IEKSRLFSEK TIRYLMQKQH EMKTQAAELQ EKPLTPLKYT KLIAAAEDGS 180
  181 RSTKDMIDAV FEQDSHLRYQ PDGVVVHRDD PALVGKLRGD LREAPADYWT HAYRDVLAQY 240
  241 HEAKERIRQK EVTAGEAQDE ASLQQQQQQD LQQQQQVVTT VASQSPHATA TEKEPVPAVV 300
  301 DDPLENMFGD YSNEPFNTNF DDEFGDLDAV FF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82
View Details	(MIPS) Mewes HW, et al. (2004)		ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 TAF14
View Details	Krogan NJ, et al. (2006)		SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82
View Details	Gavin AC, et al. (2006)		ARP9 SNF11 SNF12 SNF5 SNF6 SWI1 SWI3
View Details	Gavin AC, et al. (2002)		ARP9 BEM2 DIM1 ENP1 HRR25 LTV1 NOB1 PNO1 RIO2 RRP12 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82 TSR1 VPS1 YGR054W
View Details	Qiu et al. (2008)		ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82 TAF14

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MDM30	SNF6	2	Unpublished Fields Lab Data
View Screen	ROM2	SNF6	2	Unpublished Fields Lab Data
View Screen	ALG13	SNF6	1	Hazbun TR, et al. (2003)
View Screen	YHR022C	SNF6	1	Unpublished Fields Lab Data
View Screen	CIC1	SNF6	1	Unpublished Fields Lab Data
View Screen	NAS2	SNF6	1	Unpublished Fields Lab Data
View Screen	NTA1	SNF6	1	Unpublished Fields Lab Data
View Screen	PRR1	SNF6	1	Unpublished Fields Lab Data
View Screen	FCF2	SNF6	1	Unpublished Fields Lab Data
View Screen	CIN4	SNF6	1	Unpublished Fields Lab Data
View Screen	IGO1	SNF6	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	SNF6	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..332]	deduced	N/A	No confident structure predictions are available.
2	View Details	[63..332]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
binding	2.37238916518238	bayes_pls_golite062009
protein binding	2.11359078188979	bayes_pls_golite062009
catalytic activity	0.342991862156338	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.62

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2