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Protein Overview: PRR1

General Information:
Name(s) found: PRR1 / YKL116C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 518 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: MAPKKK cascade [IMPLink to PubMed article]
    Molecular Function: receptor signaling protein serine/threonine kinase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEYSSIYSQ PKTPRLKQEG FPDSIGDQHE KALIDENGEE DKKMASTEGT TGDSRSTPLT  60
   61 VSIPTFENVQ ALPTPMTYTP LSPGNLSMSP IDQSSLNIPK RRSHARLLDD MLSVTQPNQR 120
  121 VVSELIAPAN LSPQRVVSLP TVTEEALVND SVDSDNYTKE PYFPESSSST EKCDDDIFQG 180
  181 FLLDHWDRPL LWKKVRPIGS GNFSTVLLYE LMDQSNPKLK QVAVKRLKYP EELSNVEQIN 240
  241 TSLRYKETLS RLENSLTREL QVLKSLNHPC IVKLLGINNP IFVTSKKPLC DLIIKTPRAL 300
  301 PPCDMIMSYC PAGDLLAAVM ARNGRLEAWL IQRIFTEVVL AVKYLHENSI IHRDLKLENI 360
  361 LLKYSFDDIN SFRDSPIYCK QNFIELADFG LCKKIENNEM CTARCGSEDY VSPEILMGVP 420
  421 YDGHLSDTWA LGVILYSLFE DRLPFDPPPN ASARQRSRAT SHRIARFDWR WYRLSDYKTN 480
  481 VGKQIVENTL TRKNQRWSIN EIYESPFVKT IADTLSFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PRR1 STE23 2 Unpublished Fields Lab Data
    View Screen PRR1 ASK10 2 Uetz P, et al. (2000)
    View Screen PRR1 SOL2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PRR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] deduced N/A No confident structure predictions are available.
    2 View Details [129..173]
    [313..375]
    [499..518]    		 PSI-BLAST 257.9897 No description for 1kmwC_ was found.
    3 View Details [174..312]
    [376..498]    		 PSI-BLAST 257.9897 No description for 1kmwC_ was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle