YRC Public Data Repository - Protein Structure Prediction

Protein:	PRR1
Organism:	Saccharomyces cerevisiae
Length:	518 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRR1.

Description	E-value	Query Range	Subject Range
PRR1_YEAST - Serine/threonine-protein kinase PRR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRR... PRR1 - Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possi...	0.0	[1..518]	[1..518]
gi\|458284 - gi\|458284\|gb\|AAA57318.1\| serine/threonine protein kinase	0.0	[2..513]	[116..579]
gi\|15072452 - gi\|15072452\|gb\|AAK40343.1\| protein kinase 1 [Cryphonectria parasitica]	0.0	[2..517]	[98..561]
gi\|12005625 - gi\|12005625\|gb\|AAG44542.1\|AF247001_1 protein kinase C [Blumeria graminis]	0.0	[4..517]	[621..1100]
PKL2_RAT, PKN2_RAT - (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C-like 2) (Protein-kinase...	0.0	[35..517]	[350..789]
gi\|9716257 - gi\|9716257\|emb\|CAC01625.1\| protein kinase C homologue [Tuber borchii]	0.0	[5..517]	[637..1079]
gi\|16648134 - gi\|16648134\|gb\|AAL25332.1\| GH13631p [Drosophila melanogaster]	0.0	[94..517]	[128..489]
ENSMMUT000000444... - null, null, null, null gi\|149749105 - gi\|149749105\|ref\|XP_001492064.1\| PREDICTED: similar to protein kinase B gamma 1 isoform 2 [Equus cab... gi\|55665643, gi\|... - gi\|55666093\|emb\|CAH73072.1\| v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) ...	0.0	[136..517]	[88..414]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[136..517]	[88..414]
gi\|183396893, gi... - gi\|183396893\|gb\|AAI65948.1\| Protein kinase C, epsilon [synthetic construct], gi\|117616658\|gb\|ABK4234... KPCE_MOUSE - Protein kinase C epsilon type OS=Mus musculus GN=Prkce PE=1 SV=1	0.0	[102..517]	[315..677]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEYSSIYSQ PKTPRLKQEG FPDSIGDQHE KALIDENGEE DKKMASTEGT TGDSRSTPLT  60
   61 VSIPTFENVQ ALPTPMTYTP LSPGNLSMSP IDQSSLNIPK RRSHARLLDD MLSVTQPNQR 120
  121 VVSELIAP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [129-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANLSPQRVVS LPTVTEEALV NDSVDSDNYT KEPYFPESSS STEKC

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [313-375]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDLLAAVMAR NGRLEAWLIQ RIFTEVVLAV KYLHENSIIH RDLKLENILL KYSFDDINSF  60
   61 RDS

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [499-518]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INEIYESPFV KTIADTLSFS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	257.9897
Match:	1kmwC_
Description:	No description for 1kmwC_ was found.

Predicted Domain #3

Region A:
Residues: [174-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDIFQGFLL DHWDRPLLWK KVRPIGSGNF STVLLYELMD QSNPKLKQVA VKRLKYPEEL  60
   61 SNVEQINTSL RYKETLSRLE NSLTRELQVL KSLNHPCIVK LLGINNPIFV TSKKPLCDLI 120
  121 IKTPRALPPC DMIMSYCPA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [376-498]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIYCKQNFIE LADFGLCKKI ENNEMCTARC GSEDYVSPEI LMGVPYDGHL SDTWALGVIL  60
   61 YSLFEDRLPF DPPPNASARQ RSRATSHRIA RFDWRWYRLS DYKTNVGKQI VENTLTRKNQ 120
  121 RWS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	257.9897
Match:	1kmwC_
Description:	No description for 1kmwC_ was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits