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Protein Overview: RTN2

General Information:
Name(s) found: RTN2 / YDL204W [SGD]
Description(s) found:
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  • gi|74645057|sp|Q12443.1|RTN2_YEAST RecName: Full=Reticulon-like protein 2 [NCBI NR]
  • gi|6319997|ref|NP_010077.1| Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily; Rtn2p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|32331689|gb|AAP47372.1| Rtn2p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S67763 probable membrane protein YDL204w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1431338|emb|CAA98782.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1429353|emb|CAA67464.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Reticulon-like protein 2 OS=Saccharomyces cerevisiae GN=RTN2 PE=1 SV=1 [Swiss-Prot]
  • RTN2 Reticulon gene member of the RTNLA (reticulon-like A) subfamily [mips]
  • Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily [SGD]
  • YDL204W, Chr IV from 94606-95787 [yeast_orfs2]
  • Chr IV from 94606-95787 [yeastorf3.fasta]
  • >Q12443 (Q12443) ORF YDL204W (Rtn2p) [4932.FASTACCERV.txt]
  • RTN2 SGDID:S0002363, Chr IV from 94606-95787, Verified ORF [yeastflysequest.fasta]
  • Rtn2p [Saccharomyces cerevisiae]gi|32331689|gb|AAP47372.1| Rtn2p [Saccharomyces cerevisiae]gi|1429353|emb|CAA67464.1| unnamed protein product [Saccharomyces cerevisiae]gi|1431338|emb|CAA98782.1| unnamed protein product [Saccharomyces cerevisiae]gi|213 [nrdb_11152004_Chlamydomonas]
  • (Q12443) ORF D1062 (Rtn2p) (S.cerevisiae chromosome IV reading frame ORF YDL204w) [cerv4932.FASTAC]
  • RTN2 SGDID:S000002363, Chr IV from 94606-95787, Verified ORF, "Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily; Rtn2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Rtn2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Reticulon-like protein 2 [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Reticulon-like protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTN2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RTN2 SGDID:S000002363, Chr IV from 94605-95786, Genome Release 64-1-1, Verified ORF, "Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily" [yeast-030211-contam.fasta]
  • RTN2 SGDID:S000002363, Chr IV from 94605-95786, Genome Release 64-2-1, Verified ORF, "Reticulon protein; stabilizes membrane curvature; involved in nuclear pore assembly and maintenance of tubular ER morphology; interacts with exocyst subunit Sec6p, Yip3p, and Sbh1p; much less abundant than Rtn1p; rtn1 rtn2 yop1 triple mutant lacks tubular ER; member of RTNLA (reticulon-like A) subfamily; protein increases in abundance and relocalizes to plasma membrane upon DNA replication stress; RTN2 has a paralog, RTN1, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • TR1461|c0_g1_i1|g.1033 ORF TR1461|c0_g1_i1|g.1033 TR1461|c0_g1_i1|m.1033 type:complete len:394 (+) TR1461|c0_g1_i1:561-1742(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta]
  • YDL204W SGDID:S000002363, Chr IV from 94605-95786, Genome Release 64-1-1, Verified ORF, "Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • ID=asmbl_546|g.751 ORF ID=asmbl_546|g.751 ID=asmbl_546|m.751 type:complete len:394 (+) ID=asmbl_546:560-1741(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRNTTTNKN ANLNNSRNAN APGEAGHQNK TGLIYWTNPS KSGASFAATL VSLLILRNVN  60
   61 VISVLLKIGY MVLFTSFAVE LSTKVLFDKG VVSRFGMQES PDLVGVLKPH IDRELDRLPA 120
  121 LEDRIRKLVF AHRTRNNFTI GVSLYFLHGL FAIFSMNTVL IMTTIFLYTV PLIYDRKQAR 180
  181 IDRAIDRMKD LVIHRFHKNY NKVVEKTEPY IDKIIPPQTD EGSYSTSISN ENKSSTSQRN 240
  241 KSGLSSSEFD NMNDTSASKS GKDSYSTSQY NRAEYPVSQN ENIGTLKSGK QEIPTEKDFN 300
  301 NRHENFSKPD VKTYDPRTVD IEEELAAHQR ELEQNLKDGD YNLVGSKEIP DPITVPAPTR 360
  361 HTTKPAESQS IPIKNNETLH KTTHGLKQKL QHA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ARG4 AYR1 COR1 CPR6 ENP1 ERG27 GAR1 GPT2 HRP1 KAP104 KTR3 LIA1 MAE1 NAB2 OM45 PCT1 PDA1 PET10 PET9 PIL1 PRE10 PRO3 RET2 RNR2 RTN2 RVS161 SAC1 SEC18 SEC21 SEC26 SEC27 SEC28 TIF34 TIF35 TPA1 YDL063C YNL181W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RTN2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..249] Pfam 7.60206 Reticulon No confident structure predictions are available.
    2 View Details [250..393] deduced N/A No confident structure predictions are available.
    3 View Details [215..393] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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