| Protein: | Doa-PK |
| Organism: | Drosophila melanogaster |
| Length: | 832 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Doa-PK.
| Description | E-value | Query Range |
Subject Range |
|
|
325.0 | [0..1] | [817..1232] |
|
Region A: Residues: [1-160] |
1 11 21 31 41 51
| | | | | |
1 MVAANLEVPT SSSSSAATKR QKDVDNKLEK CLNDMLKLKT SSNNNSTSNS NNNAIMSHSL 60
61 TGEHKDPKTA LEGPTSSSSS SSSKYIGESQ IPVPVQLYDP QKPLLQQQQQ QQRICYPIGK 120
121 SNSTSQLPMG GYQRLLQHQQ QQHHQQQQQQ HQEQQQYPQH
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [161-757] |
1 11 21 31 41 51
| | | | | |
1 KRPFLNWNSF ACSAMNGASD PFMQQQHMPA HQQQQHLPHK LQQSYSSSHV PKQAPKSGLA 60
61 MFLQKNTNKE NKFGQPMQQQ PPGMMPQMYG YQAPQQQSKI GYPRTGAPLT HSASFSSAQR 120
121 PTALQFHQQH QQQQHLQQQQ QHPQQQQHQH SSFGVGMMSR NYYNMPKQPE RKPLQTFDPY 180
181 AYPKPNQMQP VKYQQQQQHP HTQFQNASAG GGGGGAAGLQ YDPNTNTQLF YASPASSSSN 240
241 KQPQQPQQQQ QQQQSQLQQS NSVIFNHSGQ QHQPHQQQQN EMSKSALGLH FIETAKPVIQ 300
301 DDADGHLIYH TGDILHHRYK IMATLGEGTF GRVVKVKDME RDYCMALKII KNVEKYREAA 360
361 KLEINALEKI AQKDPHCDHL CVKMIDWFDY HGHMCIVFEM LGLSVFDFLR ENNYEPYPLD 420
421 QVRHMAYQLC YSVKFLHDNR LTHTDLKPEN ILFVDSDYTS HYNHKINREV RRVKNTDVRL 480
481 IDFGSATFDH EHHSTIVSTR HYRAPEVILE LGWSQPCDVW SIGCILFELY LGITLFQTHD 540
541 NREHLAMMER ILGQIPYRMA RNHTLYSKTK TKYFYHGKLD WDEKSSAGRY VRDHCKP
|
| Detection Method: | |
| Confidence: | 58.69897 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| acetylcholine receptor activator activity | 5.9159846946654 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 5.68265749805481 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 4.93646793786886 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| structural molecule activity | 3.82327979736517 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| MAP kinase 2 activity | 3.27009208121248 | bayes_pls_golite062009 |
| SH2 domain binding | 3.03401803018883 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 2.68482590086393 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphodiesterase activity | 2.50158263483669 | bayes_pls_golite062009 |
| phosphoinositide phospholipase C activity | 2.50158263483669 | bayes_pls_golite062009 |
| RNA binding | 2.47233810641059 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 2.30873410607588 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 2.30873410607588 | bayes_pls_golite062009 |
| histone kinase activity (H3-S10 specific) | 2.30449166929476 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| telethonin binding | 1.75733591474207 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 1.74645334586495 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
| activin binding | 1.69795678545106 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 1.66976264488423 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| activin receptor activity | 1.64506335968643 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| PTB domain binding | 1.61518967483617 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 1.60259443694567 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.34841233233438 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.33825339298024 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 1.24312972088703 | bayes_pls_golite062009 |
| insulin binding | 1.23861703046323 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transcription repressor activity | 1.14496167267281 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.11664317075762 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| vinculin binding | 1.06656350652527 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| type II transforming growth factor beta receptor binding | 1.03605423743048 | bayes_pls_golite062009 |
| SMAD binding | 1.02108562119195 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.925299895386908 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.877087652539674 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 0.870666814073948 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| activin receptor activity, type I | 0.82317428935631 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 0.728917900114111 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 0.705634826374884 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 0.705634826374884 | bayes_pls_golite062009 |
| hormone receptor binding | 0.705067960165986 | bayes_pls_golite062009 |
| beta-catenin binding | 0.693246095477001 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activating kinase activity | 0.529121666062889 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.505233004492768 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| brain-derived neurotrophic factor binding | 0.462520151706601 | bayes_pls_golite062009 |
| transforming growth factor beta binding | 0.435457844706269 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase regulator activity | 0.406297251827056 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.399773397398032 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.318153468064373 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.240883589532225 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [758-832] |
1 11 21 31 41 51
| | | | | |
1 LFLCQLSDSE DHCELFSLIK KMLEYEPSSR ITLGEALHHP FFDRLPPHHR VGEVSNKQPL 60
61 SSGSSSRERS HSLSR
|
| Detection Method: | |
| Confidence: | 80.39794 |
| Match: | 2eu9A |
| Description: | Crystal Structure of CLK3 |
Matching Structure (courtesy of the PDB): |
|
