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Catalysis of the phosphorylation and activation of JUN kinase kinases (JNKKs). null Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. null null Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: MAP kinase kinase kinase activity
Acc: GO:0004709
Aspect: Molecular Function
Desc: Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
Synonyms:
  • cMos
  • MEKK1
  • MEKK3
  • MEKK2
  • mitogen-activated protein kinase kinase kinase activity
  • ATP:protein phosphotransferase (MAPKKKK-activated) activity
  • STK28
  • MAPKKK activity
  • MLTKa
  • MLTKb
  • Mil/Raf
  • MAP3K
  • MLTK
  • MEK kinase activity
  • MLK-like mitogen-activated protein triple kinase activity
  • cRaf
  • MEKK
  • REKS
Proteins in PDR annotated with:
   This term: 48 [Search]
   Term or descendants: 53 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004709 - MAP kinase kinase kinase activity (interactive image map)

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Created and Maintained by: Michael Riffle