Protein: | HOG1 |
Organism: | Saccharomyces cerevisiae |
Length: | 435 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOG1.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [1..435] | [1..435] |
|
0.0 | [2..346] | [21..373] |
|
0.0 | [1..348] | [32..386] |
|
0.0 | [1..350] | [37..393] |
|
0.0 | [1..350] | [33..389] |
|
0.0 | [1..363] | [1..363] |
Region A: Residues: [1-102] |
1 11 21 31 41 51 | | | | | | 1 MTTNEEFIRT QIFGTVFEIT NRYNDLNPVG MGAFGLVCSA TDTLTSQPVA IKKIMKPFST 60 61 AVLAKRTYRE LKLLKHLRHE NLICLQDIFL SPLEDIYFVT EL |
Region B: Residues: [319-382] |
1 11 21 31 41 51 | | | | | | 1 DWHFNDADLP VDTWRVMMYS EILDFHKIGG SDGQIDISAT FDDQVAAATA AAAQAQAQAQ 60 61 AQVQ |
Detection Method: | |
Confidence: | 1185.0 |
Match: | 1bmkA_ |
Description: | MAP kinase p38 |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
acetylcholine receptor activator activity | 5.9159846946654 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 5.68265749805481 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
structural molecule activity | 3.82327979736517 | bayes_pls_golite062009 |
transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
MAP kinase 2 activity | 3.27009208121248 | bayes_pls_golite062009 |
protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
phosphoinositide 3-kinase binding | 2.79505438761262 | bayes_pls_golite062009 |
binding | 2.74863538127007 | bayes_pls_golite062009 |
transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
transmembrane receptor protein serine/threonine kinase activity | 2.30873410607588 | bayes_pls_golite062009 |
transforming growth factor beta receptor activity | 2.30873410607588 | bayes_pls_golite062009 |
histone kinase activity (H3-S10 specific) | 2.30449166929476 | bayes_pls_golite062009 |
protein binding | 2.276111749106 | bayes_pls_golite062009 |
tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
actin binding | 1.87817875565699 | bayes_pls_golite062009 |
receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
telethonin binding | 1.75733591474207 | bayes_pls_golite062009 |
transforming growth factor beta receptor activity, type I | 1.74645334586495 | bayes_pls_golite062009 |
small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
activin binding | 1.69795678545106 | bayes_pls_golite062009 |
fibroblast growth factor 1 binding | 1.66976264488423 | bayes_pls_golite062009 |
purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
activin receptor activity | 1.64506335968643 | bayes_pls_golite062009 |
purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
JUN kinase kinase kinase activity | 1.60259443694567 | bayes_pls_golite062009 |
transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
ErbB-3 class receptor binding | 1.34841233233438 | bayes_pls_golite062009 |
ErbB-2 class receptor binding | 1.33825339298024 | bayes_pls_golite062009 |
kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
transcription elongation regulator activity | 1.16995153203536 | bayes_pls_golite062009 |
transcription repressor activity | 1.14496167267281 | bayes_pls_golite062009 |
transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
non-membrane spanning protein tyrosine kinase activity | 1.11664317075762 | bayes_pls_golite062009 |
transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
type II transforming growth factor beta receptor binding | 1.03605423743048 | bayes_pls_golite062009 |
SMAD binding | 1.02108562119195 | bayes_pls_golite062009 |
transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
PTB domain binding | 0.9900774724568 | bayes_pls_golite062009 |
transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
alpha-actinin binding | 0.877087652539674 | bayes_pls_golite062009 |
insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
fibroblast growth factor binding | 0.870666814073948 | bayes_pls_golite062009 |
activin receptor activity, type I | 0.82317428935631 | bayes_pls_golite062009 |
MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
receptor serine/threonine kinase binding | 0.728917900114111 | bayes_pls_golite062009 |
substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
transforming growth factor beta receptor binding | 0.705634826374884 | bayes_pls_golite062009 |
transmembrane receptor protein serine/threonine kinase binding | 0.705634826374884 | bayes_pls_golite062009 |
hormone receptor binding | 0.705067960165986 | bayes_pls_golite062009 |
beta-catenin binding | 0.693246095477001 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
cyclin-dependent protein kinase activating kinase activity | 0.529121666062889 | bayes_pls_golite062009 |
steroid hormone receptor binding | 0.505233004492768 | bayes_pls_golite062009 |
protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
transforming growth factor beta binding | 0.435457844706269 | bayes_pls_golite062009 |
protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
cyclin-dependent protein kinase regulator activity | 0.406297251827056 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
structural constituent of muscle | 0.399773397398032 | bayes_pls_golite062009 |
magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
JUN kinase kinase activity | 0.332372116912461 | bayes_pls_golite062009 |
structure-specific DNA binding | 0.318153468064373 | bayes_pls_golite062009 |
channel activity | 0.287189255116606 | bayes_pls_golite062009 |
passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
RNA binding | 0.245748631571068 | bayes_pls_golite062009 |
ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
nuclear hormone receptor binding | 0.240883589532225 | bayes_pls_golite062009 |
protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
ligase activity, forming carbon-oxygen bonds | 0.149958560815481 | bayes_pls_golite062009 |
ligase activity, forming aminoacyl-tRNA and related compounds | 0.149958560815481 | bayes_pls_golite062009 |
aminoacyl-tRNA ligase activity | 0.14842991990838 | bayes_pls_golite062009 |
peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
brain-derived neurotrophic factor binding | 0.0794053647730006 | bayes_pls_golite062009 |
nitric-oxide synthase regulator activity | 0.00407218246327123 | bayes_pls_golite062009 |
nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
Region A: Residues: [103-318] |
1 11 21 31 41 51 | | | | | | 1 QGTDLHRLLQ TRPLEKQFVQ YFLYQILRGL KYVHSAGVIH RDLKPSNILI NENCDLKICD 60 61 FGLARIQDPQ MTGYVSTRYY RAPEIMLTWQ KYDVEVDIWS AGCIFAEMIE GKPLFPGKDH 120 121 VHQFSIITDL LGSPPKDVIN TICSENTLKF VTSLPHRDPI PFSERFKTVE PDAVDLLEKM 180 181 LVFDPKKRIT AADALAHPYS APYHDPTDEP VADAKF |
Detection Method: | |
Confidence: | 1185.0 |
Match: | 1bmkA_ |
Description: | MAP kinase p38 |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [383-435] |
1 11 21 31 41 51 | | | | | | 1 LNMAAHSHNG AGTTGNDHSD IAGGNKVSDH VAANDTITDY GNQAIQYANE FQQ |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.