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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rad24. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 6.3448E-10 9 11 4 6292
replication fork 2.1099E-7 9 42 4 6292
chaperonin-containing T-complex 1.1916E-4 9 12 2 6292
protein complex 1.5852E-4 9 1137 7 6292
chromosomal part 2.13E-4 9 237 4 6292
chromosome 3.7272E-4 9 274 4 6292
non-membrane-bounded organelle 6.8534E-4 9 959 6 6292
intracellular non-membrane-bounded organelle 6.8534E-4 9 959 6 6292
macromolecular complex 1.7084E-3 9 1635 7 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 9.1317E-7 9 15 3 6292
mismatch repair 5.8201E-6 9 27 3 6292
response to DNA damage stimulus 7.9286E-6 9 236 5 6292
DNA strand elongation 8.9184E-6 9 31 3 6292
DNA strand elongation involved in DNA replication 8.9184E-6 9 31 3 6292
sister chromatid cohesion 9.834E-6 9 32 3 6292
cellular response to stress 2.174E-5 9 290 5 6292
cell cycle checkpoint 6.0045E-5 9 58 3 6292
cellular response to stimulus 7.9555E-5 9 379 5 6292
DNA repair 9.3909E-5 9 192 4 6292
DNA damage response, signal transduction 1.6406E-4 9 14 2 6292
DNA damage checkpoint 1.6406E-4 9 14 2 6292
DNA-dependent DNA replication 1.6938E-4 9 82 3 6292
response to stress 2.9062E-4 9 497 5 6292
DNA integrity checkpoint 3.4102E-4 9 20 2 6292
cell cycle 3.7665E-4 9 525 5 6292
DNA replication 5.6194E-4 9 123 3 6292
DNA metabolic process 6.2659E-4 9 585 5 6292
chromosome segregation 6.3162E-4 9 128 3 6292
regulation of cell cycle 6.7598E-4 9 131 3 6292
organelle organization 1.6714E-3 9 1127 6 6292
cellular macromolecule metabolic process 1.8315E-3 9 2285 8 6292
response to stimulus 2.1816E-3 9 766 5 6292
macromolecule metabolic process 2.2547E-3 9 2349 8 6292
cell cycle process 3.3362E-3 9 490 4 6292
protein folding 5.1625E-3 9 78 2 6292
chromosome organization 5.2635E-3 9 555 4 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA clamp loader activity 6.7465E-11 9 7 4 6292
protein-DNA loading ATPase activity 6.7465E-11 9 7 4 6292
DNA-dependent ATPase activity 6.3758E-7 9 55 4 6292
ATPase activity 4.5683E-6 9 211 5 6292
ATPase activity, coupled 3.4703E-5 9 149 4 6292
nucleoside-triphosphatase activity 4.0153E-5 9 329 5 6292
hydrolase activity, acting on acid anhydrides 5.6462E-5 9 353 5 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.6462E-5 9 353 5 6292
pyrophosphatase activity 5.6462E-5 9 353 5 6292
DNA binding 2.8694E-4 9 256 4 6292
unfolded protein binding 3.186E-3 9 61 2 6292
binding 3.5377E-3 9 1294 6 6292
hydrolase activity 4.7759E-3 9 911 5 6292

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