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A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome. Any process that modulates the rate or extent of progression through the cell cycle. The cell cycle regulatory process by which progression through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: DNA integrity checkpoint
Acc: GO:0031570
Aspect: Biological Process
Desc: Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 189 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031570 - DNA integrity checkpoint (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle