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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ylr097c. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADH2
  • cytoplasm
  • fermentation
  • ethanol metabolic process
  • NADH oxidation
  • alcohol dehydrogenase (NAD) activity
  • CDC53
  • SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding, bridging
  • GUF1
  • mitochondrion
  • biological_process
  • GTPase activity
  • HRT3
  • ubiquitin ligase complex
  • ubiquitin-dependent protein catabolic process
  • protein binding
  • IDH1
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial nucleoid
  • glutamate biosynthetic process
  • isocitrate metabolic process
  • tricarboxylic acid cycle
  • isocitrate dehydrogenase (NAD+) activity
  • SKP1
  • RAVE complex
  • nucleus
  • cytoplasm
  • CBF3 complex
  • SCF ubiquitin ligase complex
  • kinetochore
  • G2/M transition of mitotic cell cycle
  • protein complex assembly
  • regulation of exit from mitosis
  • G1/S transition of mitotic cell cycle
  • cytokinesis
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • regulation of protein complex assembly
  • protein neddylation
  • kinetochore assembly
  • vacuolar acidification
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding
  • UBI4
  • cytoplasm
  • protein deubiquitination
  • ascospore formation
  • protein polyubiquitination
  • protein monoubiquitination
  • response to stress
  • protein ubiquitination
  • protein tag
  • ATP-dependent protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ubiquitin ligase complex 1.0212E-5 7 43 3 6292
    SCF ubiquitin ligase complex 5.8081E-5 7 11 2 6292
    cullin-RING ubiquitin ligase complex 9.5944E-5 7 14 2 6292
    RAVE complex 3.3344E-3 7 3 1 6292
    CBF3 complex 4.4437E-3 7 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.2223E-5 7 7 2 6292
    protein ubiquitination 3.5765E-5 7 65 3 6292
    protein ubiquitination during ubiquitin-dependent protein catabolic process 5.8081E-5 7 11 2 6292
    protein modification by small protein conjugation 8.2954E-5 7 86 3 6292
    protein modification by small protein conjugation or removal 1.923E-4 7 114 3 6292
    G2/M transition of mitotic cell cycle 4.2467E-4 7 29 2 6292
    modification-dependent protein catabolic process 4.8635E-4 7 156 3 6292
    ubiquitin-dependent protein catabolic process 4.8635E-4 7 156 3 6292
    proteolysis involved in cellular protein catabolic process 5.1439E-4 7 159 3 6292
    cellular catabolic process 5.5642E-4 7 415 4 6292
    modification-dependent macromolecule catabolic process 5.6343E-4 7 164 3 6292
    cellular protein catabolic process 6.3701E-4 7 171 3 6292
    proteolysis 8.4091E-4 7 188 3 6292
    protein catabolic process 8.5405E-4 7 189 3 6292
    catabolic process 1.1015E-3 7 496 4 6292
    G1/S transition of mitotic cell cycle 1.2671E-3 7 50 2 6292
    cellular macromolecule catabolic process 2.279E-3 7 265 3 6292
    proteasomal protein catabolic process 2.4022E-3 7 69 2 6292
    proteasomal ubiquitin-dependent protein catabolic process 2.4022E-3 7 69 2 6292
    macromolecule catabolic process 3.0716E-3 7 294 3 6292
    centromere complex assembly 3.3344E-3 7 3 1 6292
    kinetochore assembly 3.3344E-3 7 3 1 6292
    kinetochore organization 3.3344E-3 7 3 1 6292
    interphase of mitotic cell cycle 4.6971E-3 7 97 2 6292
    interphase 4.6971E-3 7 97 2 6292
    post-translational protein modification 5.3413E-3 7 357 3 6292
    isocitrate metabolic process 5.552E-3 7 5 1 6292
    coenzyme metabolic process 7.1153E-3 7 120 2 6292
    protein neddylation 7.7654E-3 7 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA replication origin binding 8.2282E-5 7 13 2 6292
    ATP-dependent protein binding 1.1125E-3 7 1 1 6292
    sequence-specific DNA binding 1.2671E-3 7 50 2 6292
    ubiquitin-protein ligase activity 1.6447E-3 7 57 2 6292
    small conjugating protein ligase activity 1.9436E-3 7 62 2 6292
    isocitrate dehydrogenase (NAD+) activity 2.224E-3 7 2 1 6292
    protein binding 2.4409E-3 7 612 4 6292
    acid-amino acid ligase activity 2.5419E-3 7 71 2 6292
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2.6853E-3 7 73 2 6292
    oxidoreductase activity, acting on CH-OH group of donors 3.2966E-3 7 81 2 6292
    ligase activity, forming carbon-nitrogen bonds 4.4166E-3 7 94 2 6292
    isocitrate dehydrogenase activity 5.552E-3 7 5 1 6292
    alcohol dehydrogenase (NAD) activity 7.7654E-3 7 7 1 6292
    protein tag 8.8705E-3 7 8 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle