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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2002) Abstract Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 2002 Jan 10;415(6868):141-7.
Notes: From the published set of protein complexes.
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
YKU70
  • nuclear envelope
  • nuclear chromatin
  • nuclear telomeric heterochromatin
    		•
  • double-strand break repair via break-induced replication
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • chromatin assembly or disassembly
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
    		•
  • RNA binding
  • damaged DNA binding
    		•
    YKU80
  • nuclear chromatin
  • nuclear telomeric heterochromatin
    		•
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • chromatin assembly or disassembly
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
  • donor selection
    		•
  • DNA binding
  • RNA binding
  • damaged DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear telomeric heterochromatin 1.0611E-6 2 7 2 6292
    telomeric heterochromatin 1.0611E-6 2 7 2 6292
    nuclear heterochromatin 1.0611E-6 2 7 2 6292
    heterochromatin 1.0611E-6 2 7 2 6292
    nuclear chromosome, telomeric region 1.2783E-5 2 23 2 6292
    chromosome, telomeric region 1.7735E-5 2 27 2 6292
    nuclear chromatin 1.3278E-4 2 73 2 6292
    chromatin 1.4784E-4 2 77 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    double-strand break repair via homologous recombination 1.1672E-5 2 22 2 6292
    double-strand break repair via nonhomologous end joining 1.5158E-5 2 25 2 6292
    recombinational repair 1.6421E-5 2 26 2 6292
    non-recombinational repair 2.8346E-5 2 34 2 6292
    chromatin assembly or disassembly 3.0063E-5 2 35 2 6292
    double-strand break repair 8.0641E-5 2 57 2 6292
    negative regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
    chromatin silencing 2.5011E-4 2 100 2 6292
    gene silencing 2.5011E-4 2 100 2 6292
    regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
    DNA recombination 3.2544E-4 2 114 2 6292
    negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
    negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
    negative regulation of gene expression 6.7534E-4 2 164 2 6292
    negative regulation of transcription 6.7534E-4 2 164 2 6292
    negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
    negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
    negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
    chromatin organization 1.036E-3 2 203 2 6292
    negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
    negative regulation of metabolic process 1.1088E-3 2 210 2 6292
    donor selection 1.2712E-3 2 4 1 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    negative regulation of cellular process 1.5726E-3 2 250 2 6292
    negative regulation of biological process 1.6107E-3 2 253 2 6292
    anatomical structure homeostasis 2.0592E-3 2 286 2 6292
    telomere organization 2.0592E-3 2 286 2 6292
    telomere maintenance 2.0592E-3 2 286 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    double-strand break repair via break-induced replication 2.859E-3 2 9 1 6292
    regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
    regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    regulation of transcription 3.7155E-3 2 384 2 6292
    homeostatic process 4.1951E-3 2 408 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    mating type switching 5.0798E-3 2 16 1 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    mating type determination 6.3477E-3 2 20 1 6292
    sex determination 6.3477E-3 2 20 1 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    cell fate commitment 7.2981E-3 2 23 1 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292
    transcription 7.6839E-3 2 552 2 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    damaged DNA binding 2.779E-6 2 11 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    RNA binding 3.3934E-3 2 367 2 6292
    YRC Informatics Platform - Version 3.0
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