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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Set1C/COMPASS complex 3.2568E-19 6 8 6 6292
methyltransferase complex 3.2568E-19 6 8 6 6292
histone methyltransferase complex 3.2568E-19 6 8 6 6292
chromatin remodeling complex 1.3033E-11 6 99 6 6292
nucleoplasm part 3.2848E-9 6 245 6 6292
nucleoplasm 5.1651E-9 6 264 6 6292
nuclear lumen 1.3504E-7 6 453 6 6292
organelle lumen 1.3052E-6 6 660 6 6292
intracellular organelle lumen 1.3052E-6 6 660 6 6292
membrane-enclosed lumen 1.8602E-6 6 700 6 6292
nuclear part 2.8697E-5 6 1103 6 6292
protein complex 3.4445E-5 6 1137 6 6292
macromolecular complex 3.0579E-4 6 1635 6 6292
nucleus 1.1592E-3 6 2041 6 6292
organelle part 2.2664E-3 6 2282 6 6292
intracellular organelle part 2.2664E-3 6 2282 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone methylation 4.5084E-16 6 20 6 6292
protein amino acid alkylation 1.5656E-15 6 24 6 6292
protein amino acid methylation 1.5656E-15 6 24 6 6292
macromolecule methylation 7.0911E-14 6 43 6 6292
methylation 7.0911E-14 6 43 6 6292
one-carbon metabolic process 3.3719E-13 6 55 6 6292
chromatin silencing at telomere 3.3719E-13 6 55 6 6292
covalent chromatin modification 6.3035E-12 6 88 6 6292
histone modification 6.3035E-12 6 88 6 6292
negative regulation of gene expression, epigenetic 1.3865E-11 6 100 6 6292
gene silencing 1.3865E-11 6 100 6 6292
regulation of gene expression, epigenetic 1.3865E-11 6 100 6 6292
chromatin silencing 1.3865E-11 6 100 6 6292
negative regulation of transcription, DNA-dependent 2.1964E-10 6 157 6 6292
negative regulation of RNA metabolic process 2.2831E-10 6 158 6 6292
negative regulation of transcription 2.8654E-10 6 164 6 6292
negative regulation of gene expression 2.8654E-10 6 164 6 6292
chromatin modification 3.3186E-10 6 168 6 6292
negative regulation of macromolecule biosynthetic process 4.2551E-10 6 175 6 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.0509E-10 6 180 6 6292
negative regulation of nitrogen compound metabolic process 5.0509E-10 6 180 6 6292
negative regulation of biosynthetic process 6.7962E-10 6 189 6 6292
negative regulation of cellular biosynthetic process 6.7962E-10 6 189 6 6292
negative regulation of macromolecule metabolic process 7.4792E-10 6 192 6 6292
chromatin organization 1.0493E-9 6 203 6 6292
negative regulation of cellular metabolic process 1.2524E-9 6 209 6 6292
negative regulation of metabolic process 1.2892E-9 6 210 6 6292
negative regulation of cellular process 3.7127E-9 6 250 6 6292
negative regulation of biological process 3.9911E-9 6 253 6 6292
post-translational protein modification 3.2061E-8 6 357 6 6292
regulation of transcription, DNA-dependent 3.2607E-8 6 358 6 6292
regulation of RNA metabolic process 3.5457E-8 6 363 6 6292
regulation of transcription 4.9802E-8 6 384 6 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 7.9584E-8 6 415 6 6292
regulation of nitrogen compound metabolic process 8.0748E-8 6 416 6 6292
regulation of gene expression 1.2127E-7 6 445 6 6292
regulation of macromolecule biosynthetic process 1.4052E-7 6 456 6 6292
regulation of cellular biosynthetic process 1.7302E-7 6 472 6 6292
regulation of biosynthetic process 1.7524E-7 6 473 6 6292
regulation of macromolecule metabolic process 2.1155E-7 6 488 6 6292
protein modification process 2.4199E-7 6 499 6 6292
transcription, DNA-dependent 2.5393E-7 6 503 6 6292
RNA biosynthetic process 2.6954E-7 6 508 6 6292
regulation of primary metabolic process 2.8931E-7 6 514 6 6292
regulation of cellular metabolic process 3.7247E-7 6 536 6 6292
regulation of metabolic process 4.21E-7 6 547 6 6292
transcription 4.4473E-7 6 552 6 6292
chromosome organization 4.595E-7 6 555 6 6292
macromolecule modification 5.3394E-7 6 569 6 6292
small molecule metabolic process 3.0521E-6 6 760 6 6292
regulation of cellular process 4.0325E-6 6 796 6 6292
regulation of biological process 4.9653E-6 6 824 6 6292
RNA metabolic process 1.1988E-5 6 954 6 6292
cellular protein metabolic process 2.4449E-5 6 1074 6 6292
organelle organization 3.2663E-5 6 1127 6 6292
protein metabolic process 3.4263E-5 6 1136 6 6292
cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
biological regulation 5.0826E-5 6 1213 6 6292
anatomical structure homeostasis 5.8338E-5 6 286 4 6292
telomere organization 5.8338E-5 6 286 4 6292
telomere maintenance 5.8338E-5 6 286 4 6292
gene expression 7.1216E-5 6 1283 6 6292
nucleic acid metabolic process 1.283E-4 6 1415 6 6292
homeostatic process 2.354E-4 6 408 4 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3599E-4 6 1566 6 6292
cellular biosynthetic process 2.3689E-4 6 1567 6 6292
cellular component organization 2.5085E-4 6 1582 6 6292
biosynthetic process 2.7052E-4 6 1602 6 6292
cellular nitrogen compound metabolic process 4.9256E-4 6 1770 6 6292
nitrogen compound metabolic process 5.2873E-4 6 1791 6 6292
regulation of biological quality 7.5624E-4 6 551 4 6292
DNA metabolic process 9.5262E-4 6 585 4 6292
peptidyl-lysine dimethylation 9.5359E-4 6 1 1 6292
peptidyl-lysine methylation 1.9064E-3 6 2 1 6292
cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
peptidyl-lysine modification 2.8585E-3 6 3 1 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone methyltransferase activity (H3-K4 specific) 3.2568E-19 6 8 6 6292
histone methyltransferase activity 9.7705E-19 6 9 6 6292
histone-lysine N-methyltransferase activity 9.7705E-19 6 9 6 6292
lysine N-methyltransferase activity 1.996E-17 6 13 6 6292
protein-lysine N-methyltransferase activity 1.996E-17 6 13 6 6292
protein methyltransferase activity 4.5084E-16 6 20 6 6292
N-methyltransferase activity 2.0599E-15 6 25 6 6292
S-adenosylmethionine-dependent methyltransferase activity 1.1608E-12 6 67 6 6292
methyltransferase activity 1.0783E-11 6 96 6 6292
transferase activity, transferring one-carbon groups 1.3033E-11 6 99 6 6292
transferase activity 4.0631E-6 6 797 6 6292
catalytic activity 1.5845E-3 6 2150 6 6292

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