YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 20 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CMS1
  • nucleus
  • ribosome biogenesis
  • regulation of DNA replication
  • molecular_function
  • DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • MRD1
  • nuclear outer membrane
  • nucleolus
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • small-subunit processome assembly
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • rRNA primary transcript binding
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOP58
  • box C/D snoRNP complex
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
  • unfolded protein binding
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • ROK1
  • nuclear outer membrane
  • nucleolus
  • snoRNA localization
  • ribosome biogenesis
  • rRNA processing
  • ATPase activity
  • ATP-dependent RNA helicase activity
  • RRP9
  • nuclear outer membrane
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP13
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP15
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP18
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • molecular_function
  • UTP21
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP9
  • nucleus
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 6.8146E-29 20 72 16 6292
    ribonucleoprotein complex 1.125E-14 20 514 16 6292
    nuclear outer membrane 2.2012E-14 20 86 10 6292
    nuclear membrane 7.6932E-14 20 97 10 6292
    outer membrane 3.6928E-11 20 178 10 6292
    organelle outer membrane 3.6928E-11 20 178 10 6292
    nuclear envelope 1.1224E-10 20 199 10 6292
    nuclear membrane-endoplasmic reticulum network 5.1234E-10 20 232 10 6292
    nucleolus 5.5191E-9 20 211 9 6292
    endomembrane system 9.5633E-8 20 398 10 6292
    macromolecular complex 6.5307E-7 20 1635 16 6292
    envelope 8.9901E-7 20 505 10 6292
    organelle envelope 8.9901E-7 20 505 10 6292
    nuclear lumen 3.9422E-6 20 453 9 6292
    membrane part 1.0761E-5 20 662 10 6292
    organelle membrane 1.6031E-5 20 692 10 6292
    nuclear part 2.5082E-5 20 1103 12 6292
    organelle lumen 8.4213E-5 20 660 9 6292
    intracellular organelle lumen 8.4213E-5 20 660 9 6292
    membrane-enclosed lumen 1.3391E-4 20 700 9 6292
    non-membrane-bounded organelle 1.4646E-3 20 959 9 6292
    intracellular non-membrane-bounded organelle 1.4646E-3 20 959 9 6292
    membrane 1.7289E-3 20 1198 10 6292
    nucleus 2.797E-3 20 2041 13 6292
    box C/D snoRNP complex 6.3477E-3 20 2 1 6292
    intracellular part 7.7919E-3 20 4938 20 6292
    nucleolar part 8.7567E-3 20 45 2 6292
    intracellular 9.0491E-3 20 4975 20 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 6.3806E-27 20 128 17 6292
    rRNA metabolic process 2.1769E-26 20 137 17 6292
    ribosome biogenesis 3.7651E-26 20 346 20 6292
    ribonucleoprotein complex biogenesis 1.863E-25 20 374 20 6292
    maturation of SSU-rRNA 2.873E-25 20 59 14 6292
    ncRNA processing 6.5599E-23 20 215 17 6292
    ncRNA metabolic process 1.4891E-21 20 257 17 6292
    cellular component biogenesis 5.5528E-20 20 694 20 6292
    RNA processing 1.295E-18 20 380 17 6292
    RNA metabolic process 7.5676E-12 20 954 17 6292
    nucleic acid metabolic process 2.3544E-10 20 1415 18 6292
    gene expression 1.0122E-9 20 1283 17 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.392E-9 20 1566 18 6292
    cellular nitrogen compound metabolic process 1.1755E-8 20 1770 18 6292
    nitrogen compound metabolic process 1.4425E-8 20 1791 18 6292
    cellular macromolecule metabolic process 9.5116E-7 20 2285 18 6292
    macromolecule metabolic process 1.5211E-6 20 2349 18 6292
    primary metabolic process 5.0807E-5 20 2896 18 6292
    cellular metabolic process 1.0865E-4 20 3033 18 6292
    metabolic process 2.0888E-4 20 3157 18 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.3325E-4 20 13 2 6292
    cellular process 8.6878E-4 20 4426 20 6292
    rRNA modification 1.4247E-3 20 18 2 6292
    small-subunit processome assembly 3.1786E-3 20 1 1 6292
    snoRNA localization 3.1786E-3 20 1 1 6292
    ncRNA 5'-end processing 9.5071E-3 20 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5071E-3 20 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5071E-3 20 3 1 6292
    rRNA 5'-end processing 9.5071E-3 20 3 1 6292
    RNA 5'-end processing 9.5071E-3 20 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 6.3837E-33 20 31 15 6292
    RNA binding 2.7713E-15 20 367 15 6292
    nucleic acid binding 1.8924E-11 20 666 15 6292
    binding 1.9692E-8 20 1294 16 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle