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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 445.20
Complex Size: 4 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC34
  • nucleus
  • cytoplasm
  • SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • protein polyubiquitination
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • protein autoubiquitination
  • ubiquitin-protein ligase activity
  • CDC53
  • SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding, bridging
  • GRR1
  • nucleus
  • cellular bud neck contractile ring
  • nuclear ubiquitin ligase complex
  • cytoplasm
  • SCF ubiquitin ligase complex
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • response to DNA damage stimulus
  • cell cycle arrest in response to pheromone
  • protein ubiquitination
  • ubiquitin-protein ligase activity
  • protein binding
  • SKP1
  • RAVE complex
  • nucleus
  • cytoplasm
  • CBF3 complex
  • SCF ubiquitin ligase complex
  • kinetochore
  • G2/M transition of mitotic cell cycle
  • protein complex assembly
  • regulation of exit from mitosis
  • G1/S transition of mitotic cell cycle
  • cytokinesis
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • regulation of protein complex assembly
  • protein neddylation
  • kinetochore assembly
  • vacuolar acidification
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SCF ubiquitin ligase complex 5.0581E-12 4 11 4 6292
    cullin-RING ubiquitin ligase complex 1.5343E-11 4 14 4 6292
    ubiquitin ligase complex 1.8916E-9 4 43 4 6292
    protein complex 1.0617E-3 4 1137 4 6292
    RAVE complex 1.9063E-3 4 3 1 6292
    CBF3 complex 2.5411E-3 4 4 1 6292
    macromolecular complex 4.5471E-3 4 1635 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 5.3646E-13 4 7 4 6292
    G1/S transition of mitotic cell cycle 3.5299E-9 4 50 4 6292
    protein ubiquitination 1.0377E-8 4 65 4 6292
    proteasomal protein catabolic process 1.3251E-8 4 69 4 6292
    proteasomal ubiquitin-dependent protein catabolic process 1.3251E-8 4 69 4 6292
    protein ubiquitination during ubiquitin-dependent protein catabolic process 1.589E-8 4 11 3 6292
    protein modification by small protein conjugation 3.2549E-8 4 86 4 6292
    interphase of mitotic cell cycle 5.3107E-8 4 97 4 6292
    interphase 5.3107E-8 4 97 4 6292
    protein modification by small protein conjugation or removal 1.0228E-7 4 114 4 6292
    G2/M transition of mitotic cell cycle 3.5113E-7 4 29 3 6292
    modification-dependent protein catabolic process 3.6385E-7 4 156 4 6292
    ubiquitin-dependent protein catabolic process 3.6385E-7 4 156 4 6292
    proteolysis involved in cellular protein catabolic process 3.9295E-7 4 159 4 6292
    modification-dependent macromolecule catabolic process 4.4528E-7 4 164 4 6292
    cellular protein catabolic process 5.2711E-7 4 171 4 6292
    proteolysis 7.7258E-7 4 188 4 6292
    protein catabolic process 7.8928E-7 4 189 4 6292
    mitotic cell cycle 2.6373E-6 4 255 4 6292
    cellular macromolecule catabolic process 3.0787E-6 4 265 4 6292
    macromolecule catabolic process 4.6747E-6 4 294 4 6292
    post-translational protein modification 1.02E-5 4 357 4 6292
    cell cycle phase 1.2562E-5 4 376 4 6292
    cellular catabolic process 1.867E-5 4 415 4 6292
    cell cycle process 3.6367E-5 4 490 4 6292
    catabolic process 3.8187E-5 4 496 4 6292
    protein modification process 3.9123E-5 4 499 4 6292
    cell cycle 4.7965E-5 4 525 4 6292
    macromolecule modification 6.624E-5 4 569 4 6292
    protein autoubiquitination 6.3573E-4 4 1 1 6292
    cellular protein metabolic process 8.4498E-4 4 1074 4 6292
    protein metabolic process 1.058E-3 4 1136 4 6292
    centromere complex assembly 1.9063E-3 4 3 1 6292
    kinetochore assembly 1.9063E-3 4 3 1 6292
    kinetochore organization 1.9063E-3 4 3 1 6292
    protein neddylation 4.4437E-3 4 7 1 6292
    cell cycle arrest in response to pheromone 5.0773E-3 4 8 1 6292
    regulation of protein complex assembly 6.9763E-3 4 11 1 6292
    cell cycle arrest 6.9763E-3 4 11 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ubiquitin-protein ligase activity 6.0545E-9 4 57 4 6292
    small conjugating protein ligase activity 8.5504E-9 4 62 4 6292
    acid-amino acid ligase activity 1.4893E-8 4 71 4 6292
    ligase activity, forming carbon-nitrogen bonds 4.6741E-8 4 94 4 6292
    ligase activity 3.1054E-7 4 150 4 6292
    DNA replication origin binding 2.3591E-5 4 13 2 6292
    sequence-specific DNA binding 3.676E-4 4 50 2 6292
    protein binding 3.3984E-3 4 612 3 6292
    DNA binding 9.3704E-3 4 256 2 6292

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    Created and Maintained by: Michael Riffle