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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RAD3
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
    		•
  • DNA helicase activity
  • general RNA polymerase II transcription factor activity
    		•
    TFB3
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nucleotide-excision repair factor 3 complex 1.0611E-6 2 7 2 6292
    holo TFIIH complex 2.2737E-6 2 10 2 6292
    nucleotide-excision repair complex 1.0611E-5 2 21 2 6292
    DNA-directed RNA polymerase II, holoenzyme 7.7811E-5 2 56 2 6292
    transcription factor complex 1.2556E-4 2 71 2 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    nuclear lumen 5.1728E-3 2 453 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nucleotide-excision repair, DNA duplex unwinding 7.579E-7 2 6 2 6292
    regulation of transcription from RNA polymerase II promoter, mitotic 1.4147E-6 2 8 2 6292
    negative regulation of transcription from RNA polymerase II promoter, mitotic 1.4147E-6 2 8 2 6292
    regulation of transcription, mitotic 1.819E-6 2 9 2 6292
    negative regulation of transcription, mitotic 1.819E-6 2 9 2 6292
    DNA geometric change 9.6001E-6 2 20 2 6292
    DNA duplex unwinding 9.6001E-6 2 20 2 6292
    nucleotide-excision repair 3.552E-5 2 38 2 6292
    transcription initiation from RNA polymerase II promoter 5.4619E-5 2 47 2 6292
    transcription initiation 8.3521E-5 2 58 2 6292
    DNA conformation change 8.3521E-5 2 58 2 6292
    negative regulation of transcription from RNA polymerase II promoter 8.9432E-5 2 60 2 6292
    protein complex biogenesis 6.0304E-4 2 155 2 6292
    protein complex assembly 6.0304E-4 2 155 2 6292
    negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
    negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
    negative regulation of gene expression 6.7534E-4 2 164 2 6292
    negative regulation of transcription 6.7534E-4 2 164 2 6292
    negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
    negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
    negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
    negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
    negative regulation of metabolic process 1.1088E-3 2 210 2 6292
    regulation of transcription from RNA polymerase II promoter 1.3075E-3 2 228 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    negative regulation of cellular process 1.5726E-3 2 250 2 6292
    negative regulation of biological process 1.6107E-3 2 253 2 6292
    macromolecular complex assembly 1.9877E-3 2 281 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
    regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
    regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    regulation of transcription 3.7155E-3 2 384 2 6292
    cellular component assembly 3.7349E-3 2 385 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    transcription 7.6839E-3 2 552 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    general RNA polymerase II transcription factor activity 1.0186E-4 2 64 2 6292
    RNA polymerase II transcription factor activity 4.2367E-4 2 130 2 6292
    transcription regulator activity 2.8947E-3 2 339 2 6292
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    Created and Maintained by: Michael Riffle