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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ASF1
  • chromatin assembly complex
    		•
  • histone acetylation
  • DNA replication-independent nucleosome assembly
  • chromatin silencing at silent mating-type cassette
  • nucleosome disassembly
  • chromatin silencing at telomere
  • DNA replication-dependent nucleosome assembly
    		•
  • histone binding
    		•
    HAT1
  • nucleus
  • cytoplasm
  • histone acetyltransferase complex
    		•
  • histone acetylation
  • chromatin silencing at telomere
    		•
  • histone binding
    		•
    HAT2
  • nucleus
  • cytoplasm
  • histone acetyltransferase complex
    		•
  • chromatin assembly or disassembly
  • histone acetylation
  • chromatin silencing at telomere
    		•
  • histone binding
    		•
    HIF1
  • nucleus
  • histone acetyltransferase complex
    		•
  • histone acetylation
  • chromatin silencing at telomere
  • nucleosome assembly
    		•
  • histone binding
    		•
    MAM33
  • mitochondrial matrix
  • mitochondrion
    		•
  • response to drug
  • aerobic respiration
    		•
  • molecular_function
    		•
    POB3
  • nucleus
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
    		•
  • chromatin remodeling
  • DNA-dependent DNA replication
  • chromatin assembly or disassembly
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
    		•
  • chromatin binding
    		•
    PSH1
  • nucleus
    		•
  • RNA elongation from RNA polymerase II promoter
    		•
  • molecular_function
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    histone acetyltransferase complex 1.0954E-5 7 44 3 6292
    nucleoplasm part 7.1578E-5 7 245 4 6292
    nucleoplasm 9.5953E-5 7 264 4 6292
    organelle lumen 2.1944E-4 7 660 5 6292
    intracellular organelle lumen 2.1944E-4 7 660 5 6292
    membrane-enclosed lumen 2.9135E-4 7 700 5 6292
    nuclear lumen 7.7894E-4 7 453 4 6292
    FACT complex 2.224E-3 7 2 1 6292
    nuclear part 2.5214E-3 7 1103 5 6292
    protein complex 2.9048E-3 7 1137 5 6292
    nucleus 5.8629E-3 7 2041 6 6292
    alpha DNA polymerase:primase complex 7.7654E-3 7 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin assembly or disassembly 2.7758E-8 7 35 4 6292
    histone acetylation 3.1216E-8 7 36 4 6292
    protein amino acid acetylation 8.6147E-8 7 46 4 6292
    chromatin silencing at telomere 1.7942E-7 7 55 4 6292
    protein amino acid acylation 2.3907E-7 7 59 4 6292
    chromatin modification 2.5731E-7 7 168 5 6292
    chromatin organization 6.6344E-7 7 203 5 6292
    covalent chromatin modification 1.2113E-6 7 88 4 6292
    histone modification 1.2113E-6 7 88 4 6292
    transcription, DNA-dependent 1.657E-6 7 503 6 6292
    RNA biosynthetic process 1.7576E-6 7 508 6 6292
    negative regulation of gene expression, epigenetic 2.0275E-6 7 100 4 6292
    gene silencing 2.0275E-6 7 100 4 6292
    regulation of gene expression, epigenetic 2.0275E-6 7 100 4 6292
    chromatin silencing 2.0275E-6 7 100 4 6292
    transcription 2.8813E-6 7 552 6 6292
    negative regulation of transcription, DNA-dependent 1.232E-5 7 157 4 6292
    negative regulation of RNA metabolic process 1.2635E-5 7 158 4 6292
    negative regulation of transcription 1.4653E-5 7 164 4 6292
    negative regulation of gene expression 1.4653E-5 7 164 4 6292
    negative regulation of macromolecule biosynthetic process 1.8961E-5 7 175 4 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.1201E-5 7 180 4 6292
    negative regulation of nitrogen compound metabolic process 2.1201E-5 7 180 4 6292
    negative regulation of biosynthetic process 2.5722E-5 7 189 4 6292
    negative regulation of cellular biosynthetic process 2.5722E-5 7 189 4 6292
    negative regulation of macromolecule metabolic process 2.7376E-5 7 192 4 6292
    negative regulation of cellular metabolic process 3.828E-5 7 209 4 6292
    negative regulation of metabolic process 3.9008E-5 7 210 4 6292
    RNA metabolic process 7.3069E-5 7 954 6 6292
    negative regulation of cellular process 7.7489E-5 7 250 4 6292
    negative regulation of biological process 8.1203E-5 7 253 4 6292
    chromosome organization 9.4822E-5 7 555 5 6292
    nucleosome assembly 1.2639E-4 7 16 2 6292
    chromatin assembly 1.7981E-4 7 19 2 6292
    cellular macromolecule biosynthetic process 2.6203E-4 7 1187 6 6292
    macromolecule biosynthetic process 2.6461E-4 7 1189 6 6292
    post-translational protein modification 3.1112E-4 7 357 4 6292
    regulation of transcription, DNA-dependent 3.1451E-4 7 358 4 6292
    regulation of RNA metabolic process 3.3186E-4 7 363 4 6292
    gene expression 4.1171E-4 7 1283 6 6292
    regulation of transcription 4.1249E-4 7 384 4 6292
    nucleosome organization 4.2467E-4 7 29 2 6292
    DNA packaging 5.1798E-4 7 32 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.5642E-4 7 415 4 6292
    regulation of nitrogen compound metabolic process 5.616E-4 7 416 4 6292
    nucleic acid metabolic process 7.2556E-4 7 1415 6 6292
    regulation of gene expression 7.2752E-4 7 445 4 6292
    protein-DNA complex assembly 7.7096E-4 7 39 2 6292
    RNA elongation from RNA polymerase II promoter 7.7096E-4 7 39 2 6292
    regulation of macromolecule biosynthetic process 7.9889E-4 7 456 4 6292
    regulation of cellular biosynthetic process 9.1156E-4 7 472 4 6292
    regulation of biosynthetic process 9.1897E-4 7 473 4 6292
    RNA elongation 1.0268E-3 7 45 2 6292
    regulation of macromolecule metabolic process 1.0353E-3 7 488 4 6292
    nucleosome disassembly 1.1125E-3 7 1 1 6292
    DNA replication-dependent nucleosome assembly 1.1125E-3 7 1 1 6292
    DNA replication-dependent nucleosome organization 1.1125E-3 7 1 1 6292
    chromatin disassembly 1.1125E-3 7 1 1 6292
    protein-DNA complex disassembly 1.1125E-3 7 1 1 6292
    protein modification process 1.1271E-3 7 499 4 6292
    regulation of primary metabolic process 1.2617E-3 7 514 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.3005E-3 7 1566 6 6292
    cellular biosynthetic process 1.3053E-3 7 1567 6 6292
    regulation of cellular metabolic process 1.4794E-3 7 536 4 6292
    biosynthetic process 1.4816E-3 7 1602 6 6292
    regulation of metabolic process 1.5978E-3 7 547 4 6292
    DNA conformation change 1.7026E-3 7 58 2 6292
    macromolecule modification 1.8549E-3 7 569 4 6292
    cellular nitrogen compound metabolic process 2.6186E-3 7 1770 6 6292
    macromolecular complex assembly 2.6978E-3 7 281 3 6292
    organelle organization 2.7877E-3 7 1127 5 6292
    nitrogen compound metabolic process 2.8003E-3 7 1791 6 6292
    macromolecular complex subunit organization 5.3413E-3 7 357 3 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    regulation of cellular process 6.4862E-3 7 796 4 6292
    cellular component assembly 6.6113E-3 7 385 3 6292
    DNA replication-independent nucleosome assembly 6.6592E-3 7 6 1 6292
    DNA replication-independent nucleosome organization 6.6592E-3 7 6 1 6292
    regulation of biological process 7.3628E-3 7 824 4 6292
    metabolic process 7.9792E-3 7 3157 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    histone binding 5.3495E-10 7 14 4 6292
    protein binding 2.4409E-3 7 612 4 6292
    binding 5.2851E-3 7 1294 5 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle