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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U5 snRNP 1.7475E-7 6 14 3 6292
ribonucleoprotein complex 2.8931E-7 6 514 6 6292
U4/U6 x U5 tri-snRNP complex 2.3659E-6 6 32 3 6292
small nuclear ribonucleoprotein complex 1.8732E-5 6 63 3 6292
nuclear part 2.8697E-5 6 1103 6 6292
macromolecular complex 3.0579E-4 6 1635 6 6292
spliceosomal complex 7.3675E-4 6 45 2 6292
nucleus 1.1592E-3 6 2041 6 6292
organelle part 2.2664E-3 6 2282 6 6292
intracellular organelle part 2.2664E-3 6 2282 6 6292
nuclear outer membrane 2.6729E-3 6 86 2 6292
nuclear cap binding complex 2.8585E-3 6 3 1 6292
nuclear membrane 3.389E-3 6 97 2 6292
RNA cap binding complex 5.7102E-3 6 6 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mRNA metabolic process 2.4781E-7 6 213 5 6292
nuclear mRNA splicing, via spliceosome 8.4468E-7 6 99 4 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 8.7965E-7 6 100 4 6292
RNA splicing, via transesterification reactions 1.1556E-6 6 107 4 6292
RNA splicing 2.6883E-6 6 132 4 6292
RNA processing 4.4689E-6 6 380 5 6292
mRNA processing 5.2488E-6 6 156 4 6292
RNA metabolic process 1.1988E-5 6 954 6 6292
spliceosomal conformational changes to generate catalytic conformation 2.7204E-5 6 9 2 6292
ribonucleoprotein complex assembly 5.862E-5 6 92 3 6292
nucleic acid metabolic process 1.283E-4 6 1415 6 6292
ribonucleoprotein complex biogenesis 1.675E-4 6 374 4 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3599E-4 6 1566 6 6292
cellular macromolecular complex assembly 4.465E-4 6 182 3 6292
cellular nitrogen compound metabolic process 4.9256E-4 6 1770 6 6292
nitrogen compound metabolic process 5.2873E-4 6 1791 6 6292
regulation of hormone levels 9.5359E-4 6 1 1 6292
hormone metabolic process 9.5359E-4 6 1 1 6292
hormone biosynthetic process 9.5359E-4 6 1 1 6292
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) 9.5359E-4 6 1 1 6292
auxin biosynthetic process 9.5359E-4 6 1 1 6292
auxin metabolic process 9.5359E-4 6 1 1 6292
cellular macromolecular complex subunit organization 1.2572E-3 6 259 3 6292
macromolecular complex assembly 1.5941E-3 6 281 3 6292
mRNA catabolic process 1.7281E-3 6 69 2 6292
gene expression 1.746E-3 6 1283 5 6292
cellular component biogenesis 1.8339E-3 6 694 4 6292
nuclear mRNA 3'-splice site recognition 1.9064E-3 6 2 1 6292
cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
RNA catabolic process 2.3169E-3 6 80 2 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
generation of catalytic spliceosome for first transesterification step 2.8585E-3 6 3 1 6292
macromolecular complex subunit organization 3.1855E-3 6 357 3 6292
cellular component assembly 3.9564E-3 6 385 3 6292
cellular component organization 4.7462E-3 6 1582 5 6292
traversing start control point of mitotic cell cycle 5.7102E-3 6 6 1 6292
mRNA splice site selection 5.7102E-3 6 6 1 6292
response to exogenous dsRNA 6.6592E-3 6 7 1 6292
response to dsRNA 6.6592E-3 6 7 1 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U5 snRNA binding 7.579E-7 6 2 2 6292
snRNA binding 7.5694E-6 6 5 2 6292
ATP-dependent RNA helicase activity 2.8334E-4 6 28 2 6292
RNA-dependent ATPase activity 3.042E-4 6 29 2 6292
RNA helicase activity 6.4156E-4 6 42 2 6292
ATP-dependent helicase activity 8.3837E-4 6 48 2 6292
purine NTP-dependent helicase activity 8.3837E-4 6 48 2 6292
5'-3' exoribonuclease activity 1.9064E-3 6 2 1 6292
helicase activity 2.4918E-3 6 83 2 6292
nucleoside-triphosphatase activity 2.5174E-3 6 329 3 6292
hydrolase activity, acting on acid anhydrides 3.0839E-3 6 353 3 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.0839E-3 6 353 3 6292
pyrophosphatase activity 3.0839E-3 6 353 3 6292
RNA binding 3.4488E-3 6 367 3 6292
recombinase activity 3.8098E-3 6 4 1 6292
hydrolase activity 5.1329E-3 6 911 4 6292
5'-3' exonuclease activity 5.7102E-3 6 6 1 6292
ATPase activity, coupled 7.8493E-3 6 149 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle