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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARX1
  • cytoplasm
  • nucleoplasm
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • DBP10
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • DRS1
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • ERB1
  • nucleus
  • nucleolus
  • rRNA processing
  • molecular_function
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • NIP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • molecular_function
  • NOC3
  • nucleus
  • Noc2p-Noc3p complex
  • nucleolus
  • DNA replication initiation
  • ribosome biogenesis
  • rRNA processing
  • protein binding
  • chromatin binding
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NOP15
  • nucleus
  • nucleolus
  • cytokinesis, actomyosin contractile ring assembly
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOP7
  • nucleus
  • nucleolus
  • cell proliferation
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • cell cycle
  • molecular_function
  • NSA1
  • nucleus
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • RIX1
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • RIX7
  • nucleus
  • nucleolus
  • ribosomal large subunit export from nucleus
  • ATPase activity
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 1.6793E-19 16 211 14 6292
    nuclear lumen 4.0631E-19 16 453 16 6292
    organelle lumen 1.823E-16 16 660 16 6292
    intracellular organelle lumen 1.823E-16 16 660 16 6292
    membrane-enclosed lumen 4.7232E-16 16 700 16 6292
    nuclear part 7.2679E-13 16 1103 16 6292
    non-membrane-bounded organelle 2.9855E-10 16 959 14 6292
    intracellular non-membrane-bounded organelle 2.9855E-10 16 959 14 6292
    nucleus 1.444E-8 16 2041 16 6292
    organelle part 8.6662E-8 16 2282 16 6292
    intracellular organelle part 8.6662E-8 16 2282 16 6292
    nuclear outer membrane 5.2245E-5 16 86 4 6292
    nuclear membrane 8.3815E-5 16 97 4 6292
    nuclear envelope 9.8913E-5 16 199 5 6292
    preribosome, large subunit precursor 2.1602E-4 16 9 2 6292
    membrane-bounded organelle 2.7361E-4 16 3771 16 6292
    intracellular membrane-bounded organelle 2.7361E-4 16 3771 16 6292
    outer membrane 8.6327E-4 16 178 4 6292
    organelle outer membrane 8.6327E-4 16 178 4 6292
    intracellular organelle 9.2974E-4 16 4070 16 6292
    organelle 9.334E-4 16 4071 16 6292
    nuclear membrane-endoplasmic reticulum network 2.3097E-3 16 232 4 6292
    endomembrane system 2.4092E-3 16 398 5 6292
    preribosome 3.2438E-3 16 34 2 6292
    Noc2p-Noc3p complex 5.0798E-3 16 2 1 6292
    envelope 6.7707E-3 16 505 5 6292
    organelle envelope 6.7707E-3 16 505 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 5.0115E-21 16 346 16 6292
    ribonucleoprotein complex biogenesis 1.7877E-20 16 374 16 6292
    ribosomal large subunit biogenesis 2.4731E-19 16 65 11 6292
    cellular component biogenesis 4.1092E-16 16 694 16 6292
    ribosome assembly 3.7233E-7 16 64 5 6292
    rRNA processing 4.2723E-7 16 128 6 6292
    organelle assembly 5.4481E-7 16 69 5 6292
    rRNA metabolic process 6.3938E-7 16 137 6 6292
    ribonucleoprotein complex assembly 2.3047E-6 16 92 5 6292
    ribosomal large subunit assembly 2.6696E-6 16 41 4 6292
    ribosomal subunit assembly 8.7997E-6 16 55 4 6292
    ncRNA processing 8.925E-6 16 215 6 6292
    ncRNA metabolic process 2.4836E-5 16 257 6 6292
    establishment of ribosome localization 3.3857E-5 16 26 3 6292
    ribosome localization 3.3857E-5 16 26 3 6292
    ribosomal subunit export from nucleus 3.3857E-5 16 26 3 6292
    cellular macromolecular complex assembly 6.46E-5 16 182 5 6292
    RNA processing 2.2235E-4 16 380 6 6292
    establishment of organelle localization 3.2659E-4 16 55 3 6292
    cellular macromolecular complex subunit organization 3.4181E-4 16 259 5 6292
    macromolecular complex assembly 4.9873E-4 16 281 5 6292
    organelle localization 1.1736E-3 16 85 3 6292
    macromolecular complex subunit organization 1.484E-3 16 357 5 6292
    nuclear export 2.0433E-3 16 103 3 6292
    cellular component assembly 2.0794E-3 16 385 5 6292
    cellular process 3.565E-3 16 4426 16 6292
    nuclear transport 3.9636E-3 16 130 3 6292
    nucleocytoplasmic transport 3.9636E-3 16 130 3 6292
    actomyosin structure organization 7.6106E-3 16 3 1 6292
    cytokinesis, actomyosin contractile ring assembly 7.6106E-3 16 3 1 6292
    assembly of actomyosin apparatus involved in cell cycle cytokinesis 7.6106E-3 16 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ATP-dependent RNA helicase activity 4.2528E-5 16 28 3 6292
    RNA-dependent ATPase activity 4.7361E-5 16 29 3 6292
    RNA helicase activity 1.4582E-4 16 42 3 6292
    ATP-dependent helicase activity 2.1767E-4 16 48 3 6292
    purine NTP-dependent helicase activity 2.1767E-4 16 48 3 6292
    nucleoside-triphosphatase activity 1.0264E-3 16 329 5 6292
    helicase activity 1.0951E-3 16 83 3 6292
    hydrolase activity, acting on acid anhydrides 1.4107E-3 16 353 5 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.4107E-3 16 353 5 6292
    pyrophosphatase activity 1.4107E-3 16 353 5 6292
    ATPase activity 1.6283E-3 16 211 4 6292
    ATPase activity, coupled 5.8113E-3 16 149 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle