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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADA2
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • transcription coactivator activity
  • GCN5
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • histone acetyltransferase activity
  • transcription coactivator activity
  • HFI1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • histone acetylation
  • transcription cofactor activity
  • transcription coactivator activity
  • NGG1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • response to drug
  • histone acetylation
  • transcription cofactor activity
  • SGF11
  • nucleus
  • SAGA complex
  • regulation of transcription from RNA polymerase II promoter
  • histone deubiquitination
  • molecular_function
  • SGF73
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • histone acetyltransferase activity
  • structural molecule activity
  • SPT20
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • transcription cofactor activity
  • SPT7
  • SLIK (SAGA-like) complex
  • mitochondrion
  • SAGA complex
  • chromatin modification
  • protein complex assembly
  • conjugation with cellular fusion
  • histone acetylation
  • structural molecule activity
  • TAF10
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF12
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF5
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF6
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SAGA complex 8.1301E-32 12 22 12 6292
    SAGA-type complex 1.6999E-31 12 23 12 6292
    SLIK (SAGA-like) complex 3.4469E-30 12 16 11 6292
    histone acetyltransferase complex 2.6517E-27 12 44 12 6292
    nucleoplasm part 9.3372E-18 12 245 12 6292
    nucleoplasm 2.3343E-17 12 264 12 6292
    nuclear lumen 1.6922E-14 12 453 12 6292
    organelle lumen 1.6216E-12 12 660 12 6292
    intracellular organelle lumen 1.6216E-12 12 660 12 6292
    membrane-enclosed lumen 3.3044E-12 12 700 12 6292
    Ada2/Gcn5/Ada3 transcription activator complex 3.7897E-11 12 5 4 6292
    nuclear part 8.0153E-10 12 1103 12 6292
    protein complex 1.1559E-9 12 1137 12 6292
    transcription factor TFIID complex 1.0241E-8 12 15 4 6292
    macromolecular complex 9.1989E-8 12 1635 12 6292
    nucleus 1.3278E-6 12 2041 12 6292
    DNA-directed RNA polymerase II, holoenzyme 2.6426E-6 12 56 4 6292
    organelle part 5.0851E-6 12 2282 12 6292
    intracellular organelle part 5.0851E-6 12 2282 12 6292
    transcription factor complex 6.8843E-6 12 71 4 6292
    membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular organelle 5.3355E-3 12 4070 12 6292
    organelle 5.3513E-3 12 4071 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetylation 4.7272E-25 12 36 11 6292
    protein amino acid acetylation 1.0481E-23 12 46 11 6292
    covalent chromatin modification 2.5821E-23 12 88 12 6292
    histone modification 2.5821E-23 12 88 12 6292
    protein amino acid acylation 2.1947E-22 12 59 11 6292
    chromatin modification 8.8748E-20 12 168 12 6292
    chromatin organization 9.2279E-19 12 203 12 6292
    post-translational protein modification 9.3314E-16 12 357 12 6292
    protein modification process 5.4754E-14 12 499 12 6292
    chromosome organization 1.9889E-13 12 555 12 6292
    macromolecule modification 2.6898E-13 12 569 12 6292
    cellular protein metabolic process 5.8125E-10 12 1074 12 6292
    organelle organization 1.0391E-9 12 1127 12 6292
    protein metabolic process 1.1437E-9 12 1136 12 6292
    regulation of transcription involved in G1 phase of mitotic cell cycle 7.5177E-9 12 14 4 6292
    cellular component organization 6.186E-8 12 1582 12 6292
    G1 phase of mitotic cell cycle 1.3007E-7 12 27 4 6292
    G1 phase 1.3007E-7 12 27 4 6292
    transcription initiation from RNA polymerase II promoter 1.2952E-6 12 47 4 6292
    transcription initiation 3.0463E-6 12 58 4 6292
    cellular macromolecule metabolic process 5.1661E-6 12 2285 12 6292
    protein complex biogenesis 5.8596E-6 12 155 5 6292
    protein complex assembly 5.8596E-6 12 155 5 6292
    macromolecule metabolic process 7.2022E-6 12 2349 12 6292
    transcription from RNA polymerase II promoter 1.5323E-5 12 335 6 6292
    interphase of mitotic cell cycle 2.3903E-5 12 97 4 6292
    interphase 2.3903E-5 12 97 4 6292
    regulation of transcription from RNA polymerase II promoter 3.8456E-5 12 228 5 6292
    primary metabolic process 8.9282E-5 12 2896 12 6292
    macromolecular complex assembly 1.0483E-4 12 281 5 6292
    transcription, DNA-dependent 1.5424E-4 12 503 6 6292
    cellular metabolic process 1.5563E-4 12 3033 12 6292
    RNA biosynthetic process 1.6301E-4 12 508 6 6292
    metabolic process 2.5194E-4 12 3157 12 6292
    transcription 2.5881E-4 12 552 6 6292
    macromolecular complex subunit organization 3.2502E-4 12 357 5 6292
    regulation of transcription, DNA-dependent 3.2931E-4 12 358 5 6292
    regulation of RNA metabolic process 3.5139E-4 12 363 5 6292
    regulation of transcription 4.5684E-4 12 384 5 6292
    cellular component assembly 4.624E-4 12 385 5 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 6.5486E-4 12 415 5 6292
    regulation of nitrogen compound metabolic process 6.6218E-4 12 416 5 6292
    regulation of gene expression 9.0312E-4 12 445 5 6292
    mitotic cell cycle 1.0081E-3 12 255 4 6292
    regulation of macromolecule biosynthetic process 1.0101E-3 12 456 5 6292
    regulation of cellular biosynthetic process 1.1824E-3 12 472 5 6292
    regulation of biosynthetic process 1.1939E-3 12 473 5 6292
    regulation of macromolecule metabolic process 1.3762E-3 12 488 5 6292
    regulation of primary metabolic process 1.7409E-3 12 514 5 6292
    histone deubiquitination 1.9072E-3 12 1 1 6292
    regulation of cellular metabolic process 2.1025E-3 12 536 5 6292
    regulation of metabolic process 2.3031E-3 12 547 5 6292
    cell cycle phase 4.2307E-3 12 376 4 6292
    RNA metabolic process 4.8607E-3 12 954 6 6292
    cellular component biogenesis 6.5683E-3 12 694 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription regulator activity 6.577E-10 12 339 9 6292
    transcription cofactor activity 6.1482E-9 12 40 5 6292
    transcription factor binding 8.9691E-9 12 43 5 6292
    general RNA polymerase II transcription factor activity 4.5342E-6 12 64 4 6292
    transcription coactivator activity 6.9162E-6 12 21 3 6292
    RNA polymerase II transcription factor activity 7.5748E-5 12 130 4 6292
    transcription activator activity 1.7927E-4 12 61 3 6292
    histone acetyltransferase activity 4.4637E-4 12 17 2 6292
    lysine N-acetyltransferase activity 4.4637E-4 12 17 2 6292
    N-acetyltransferase activity 1.7038E-3 12 33 2 6292
    N-acyltransferase activity 2.2566E-3 12 38 2 6292
    protein binding 3.7937E-3 12 612 5 6292
    acetyltransferase activity 3.8824E-3 12 50 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle