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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.638799765259]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 7.2981E-3 2 23 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
negative regulation of transcription 6.7534E-4 2 164 2 6292
negative regulation of gene expression 6.7534E-4 2 164 2 6292
negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
regulation of transcription, mating-type specific 1.5888E-3 2 5 1 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
developmental process 2.7595E-3 2 331 2 6292
loss of chromatin silencing involved in replicative cell aging 2.859E-3 2 9 1 6292
progressive alteration of chromatin involved in replicative cell aging 3.1764E-3 2 10 1 6292
loss of chromatin silencing 3.1764E-3 2 10 1 6292
regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
progressive alteration of chromatin involved in cell aging 3.4937E-3 2 11 1 6292
positive regulation of gene expression, epigenetic 3.4937E-3 2 11 1 6292
regulation of gene silencing 3.4937E-3 2 11 1 6292
negative regulation of gene silencing 3.4937E-3 2 11 1 6292
regulation of chromatin silencing 3.4937E-3 2 11 1 6292
negative regulation of chromatin silencing 3.4937E-3 2 11 1 6292
regulation of transcription 3.7155E-3 2 384 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
regulation of gene expression 4.9915E-3 2 445 2 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
chromatin silencing at rDNA 5.7138E-3 2 18 1 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
mating type determination 6.3477E-3 2 20 1 6292
sex determination 6.3477E-3 2 20 1 6292
transcription, DNA-dependent 6.3792E-3 2 503 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
cell fate commitment 7.2981E-3 2 23 1 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
transcription 7.6839E-3 2 552 2 6292
double-strand break repair via nonhomologous end joining 7.9314E-3 2 25 1 6292
histone deacetylation 8.5646E-3 2 27 1 6292
protein amino acid deacetylation 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase activity 2.5061E-5 2 32 2 6292
protein deacetylase activity 2.5061E-5 2 32 2 6292
deacetylase activity 3.0063E-5 2 35 2 6292
transcription repressor activity 4.7798E-5 2 44 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5.6994E-5 2 48 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.5966E-4 2 80 2 6292
transcription regulator activity 2.8947E-3 2 339 2 6292
specific transcriptional repressor activity 4.7627E-3 2 15 1 6292
transcription corepressor activity 5.0798E-3 2 16 1 6292
transcription coactivator activity 6.6645E-3 2 21 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle