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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ACC1
  • endoplasmic reticulum membrane
  • mitochondrion
  • cytosol
  • nuclear envelope organization
  • protein import into nucleus
  • fatty acid biosynthetic process
  • acetyl-CoA carboxylase activity
  • biotin carboxylase activity
  • CCT8
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CLU1
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • mitochondrion organization
  • molecular_function
  • CPA2
  • carbamoyl-phosphate synthase complex
  • arginine biosynthetic process
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
  • FDH1
  • cytosol
  • NADH regeneration
  • formate catabolic process
  • formate dehydrogenase activity
  • GCN20
  • cytosol
  • regulation of translational elongation
  • ATPase activity
  • GFA1
  • cellular_component
  • cell wall chitin biosynthetic process
  • glutamine-fructose-6-phosphate transaminase (isomerizing) activity
  • GUS1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • glutamyl-tRNA aminoacylation
  • glutamate-tRNA ligase activity
  • ILV1
  • mitochondrion
  • branched chain family amino acid biosynthetic process
  • L-threonine ammonia-lyase activity
  • KAP123
  • nucleus
  • cytoplasm
  • nuclear pore
  • protein import into nucleus
  • protein transmembrane transporter activity
  • LYS12
  • mitochondrion
  • lysine biosynthetic process
  • homoisocitrate dehydrogenase activity
  • MRPL3
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • PSA1
  • cytoplasm
  • cell wall mannoprotein biosynthetic process
  • GDP-mannose biosynthetic process
  • protein amino acid glycosylation
  • mannose-1-phosphate guanylyltransferase activity
  • RPA135
  • DNA-directed RNA polymerase I complex
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
  • DNA-directed RNA polymerase activity
  • RPB2
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPN10
  • proteasome regulatory particle, base subcomplex
  • proteasome complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN11
  • nucleus
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN12
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN8
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPT3
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT5
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT6
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • SAM1
  • cytoplasm
  • methionine metabolic process
  • methionine adenosyltransferase activity
  • SEC27
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • SMC3
  • nucleus
  • nuclear cohesin complex
  • ascospore formation
  • mitotic sister chromatid cohesion
  • synaptonemal complex assembly
  • ATPase activity
  • TCB1
  • mitochondrion
  • biological_process
  • lipid binding
  • TIF1, TIF2
  • plasma membrane enriched fraction
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • regulation of translation
  • translational initiation
  • regulation of translational initiation
  • translation
  • nucleotide binding
  • nucleic acid binding
  • translation initiation factor activity
  • ATP binding
  • RNA binding
  • ATP-dependent helicase activity
  • helicase activity
  • ATP-dependent RNA helicase activity
  • hydrolase activity
  • TSA1
  • cytoplasm
  • response to oxidative stress
  • thioredoxin peroxidase activity
  • unfolded protein binding
  • peroxiredoxin activity
  • TUB3
  • tubulin complex
  • kinetochore microtubule
  • spindle pole body
  • polar microtubule
  • nuclear microtubule
  • cytoplasmic microtubule
  • homologous chromosome segregation
  • mitotic sister chromatid segregation
  • nuclear migration along microtubule
  • nuclear migration during conjugation with cellular fusion
  • structural constituent of cytoskeleton
  • URA7
  • cytosol
  • CTP biosynthetic process
  • phospholipid biosynthetic process
  • pyrimidine base biosynthetic process
  • CTP synthase activity
  • VAS1
  • cytoplasm
  • mitochondrion
  • valyl-tRNA aminoacylation
  • valine-tRNA ligase activity
  • YOL098C
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome accessory complex 1.0108E-11 32 23 7 6292
    proteasome regulatory particle 1.0108E-11 32 23 7 6292
    proteasome complex 2.7817E-9 32 48 7 6292
    proteasome regulatory particle, base subcomplex 6.822E-8 32 9 4 6292
    protein complex 1.3461E-6 32 1137 18 6292
    proteasome regulatory particle, lid subcomplex 1.4E-5 32 10 3 6292
    macromolecular complex 6.4636E-5 32 1635 19 6292
    intracellular part 4.1259E-3 32 4938 31 6292
    intracellular 5.0801E-3 32 4975 31 6292
    plasma membrane enriched fraction 5.0858E-3 32 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    modification-dependent protein catabolic process 1.006E-5 32 156 7 6292
    ubiquitin-dependent protein catabolic process 1.006E-5 32 156 7 6292
    proteolysis involved in cellular protein catabolic process 1.1403E-5 32 159 7 6292
    modification-dependent macromolecule catabolic process 1.3973E-5 32 164 7 6292
    cellular protein catabolic process 1.8363E-5 32 171 7 6292
    proteolysis 3.3956E-5 32 188 7 6292
    protein catabolic process 3.5137E-5 32 189 7 6292
    cellular protein metabolic process 8.6439E-5 32 1074 15 6292
    protein metabolic process 1.676E-4 32 1136 15 6292
    amine metabolic process 1.7281E-4 32 243 7 6292
    organic acid metabolic process 1.9439E-4 32 333 8 6292
    oxoacid metabolic process 1.9439E-4 32 333 8 6292
    carboxylic acid metabolic process 1.9439E-4 32 333 8 6292
    primary metabolic process 2.0926E-4 32 2896 25 6292
    cellular ketone metabolic process 2.5311E-4 32 346 8 6292
    cellular macromolecule catabolic process 2.9528E-4 32 265 7 6292
    cellular amino acid metabolic process 4.2284E-4 32 199 6 6292
    cellular metabolic process 5.1268E-4 32 3033 25 6292
    macromolecule catabolic process 5.5529E-4 32 294 7 6292
    cellular amine metabolic process 7.5637E-4 32 222 6 6292
    metabolic process 1.0941E-3 32 3157 25 6292
    cellular amino acid and derivative metabolic process 1.2135E-3 32 243 6 6292
    small molecule metabolic process 3.3241E-3 32 760 10 6292
    cellular catabolic process 4.1059E-3 32 415 7 6292
    small molecule biosynthetic process 4.1645E-3 32 310 6 6292
    carboxylic acid biosynthetic process 5.074E-3 32 139 4 6292
    organic acid biosynthetic process 5.074E-3 32 139 4 6292
    valyl-tRNA aminoacylation 5.0858E-3 32 1 1 6292
    cell wall macromolecule biosynthetic process 5.4328E-3 32 22 2 6292
    cellular component macromolecule biosynthetic process 5.4328E-3 32 22 2 6292
    cellular biosynthetic process 5.626E-3 32 1567 15 6292
    cellular cell wall macromolecule metabolic process 5.9314E-3 32 23 2 6292
    cellular process 6.0296E-3 32 4426 29 6292
    cell wall macromolecule metabolic process 6.4502E-3 32 24 2 6292
    biosynthetic process 7.0125E-3 32 1602 15 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endopeptidase activity 2.295E-7 32 54 6 6292
    peptidase activity, acting on L-amino acid peptides 6.6722E-6 32 95 6 6292
    catalytic activity 1.4344E-5 32 2150 23 6292
    peptidase activity 3.4879E-4 32 192 6 6292
    ATPase activity 5.78E-4 32 211 6 6292
    ligase activity 8.6245E-4 32 150 5 6292
    biotin carboxylase activity 5.0858E-3 32 1 1 6292
    mannose-1-phosphate guanylyltransferase activity 5.0858E-3 32 1 1 6292
    homoisocitrate dehydrogenase activity 5.0858E-3 32 1 1 6292
    mannose-phosphate guanylyltransferase activity 5.0858E-3 32 1 1 6292
    glutamine-fructose-6-phosphate transaminase (isomerizing) activity 5.0858E-3 32 1 1 6292
    valine-tRNA ligase activity 5.0858E-3 32 1 1 6292
    nucleoside-triphosphatase activity 5.5719E-3 32 329 6 6292
    hydrolase activity, acting on acid anhydrides 7.8194E-3 32 353 6 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.8194E-3 32 353 6 6292
    pyrophosphatase activity 7.8194E-3 32 353 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle