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Protein Overview: Y1461_ARATH

General Information:
Name(s) found: Y1461_ARATH [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Probable serine/threonine-protein kinase At1g54610 OS=Arabidopsis thaliana GN=At1g54610 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 572 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: protein amino acid phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [IEA]
    protein kinase activity [IEA]
    protein serine/threonine kinase activity [IEA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCVFGREAA TTTTAEAKQA KSSKASSGVV VVGESSVTKS NGVIADDVEK KKNEEANGDK  60
   61 ERKSSKGDRR RSTKPNPRLS NPSKHWRGEQ VAAGWPSWLS DACGEALNGW VPRKADTFEK 120
  121 IDKIGQGTYS NVYKAKDMLT GKIVALKKVR FDNLEPESVK FMAREILVLR RLDHPNVVKL 180
  181 EGLVTSRMSC SLYLVFQYMD HDLAGLASSP VVKFSESEVK CLMRQLISGL EHCHSRGVLH 240
  241 RDIKGSNLLI DDGGVLKIAD FGLATIFDPN HKRPMTSRVV TLWYRAPELL LGATDYGVGI 300
  301 DLWSAGCILA ELLAGRPIMP GRTEVEQLHK IYKLCGSPSE DYWKKGKFTH GAIYKPREPY 360
  361 KRSIRETFKD FPPSSLPLID ALLSIEPEDR QTASAALKSE FFTSEPYACE PADLPKYPPS 420
  421 KEIDAKRRDE ETRRQRAASK AQGDGARKNR HRDRSNRALP APEANAELQS NVDRRRLITH 480
  481 ANAKSKSEKF PPPHQDGGAM GVPLGASQHI DPTFIPRDMV PSFTSSSFNF SKDEPPTQVQ 540
  541 TWSGPLGHPI TGVSRKKKDN TKSSKGKRAV VA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..365] PSI-BLAST 48.69897 Carboxyl-terminal src kinase (csk)
    2 View Details [366..464] FFAS03 2.36 THE C-JUN N-TERMINAL KINASE (JNK3S) COMPLEXED WITH MGAMP-PNP
    3 View Details [465..572] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetylcholine receptor activator activity
    		•  5.9159846946654 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.68265749805481 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  4.62392503670521 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • structural molecule activity
    		•  3.82327979736517 bayes_pls_golite062009
  • insulin receptor binding
    		•  3.48393497211158 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  3.40140621607334 bayes_pls_golite062009
  • MAP kinase 2 activity
    		•  3.27009208121248 bayes_pls_golite062009
  • protein binding
    		•  3.19631993182765 bayes_pls_golite062009
  • signal transducer activity
    		•  3.13508395312263 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.13508395312263 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  3.13034625475504 bayes_pls_golite062009
  • binding
    		•  3.12724619324809 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.84750782193308 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  2.79505438761262 bayes_pls_golite062009
  • phosphoinositide 3-kinase regulator activity
    		•  2.68482590086393 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.58256379852715 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.52531786618214 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphodiesterase activity
    		•  2.50158263483669 bayes_pls_golite062009
  • phosphoinositide phospholipase C activity
    		•  2.50158263483669 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.46424348876434 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.37122853419919 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.32209932468336 bayes_pls_golite062009
  • histone kinase activity (H3-S10 specific)
    		•  2.30449166929476 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09146786953566 bayes_pls_golite062009
  • RNA polymerase II transcription mediator activity
    		•  2.01834365480663 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • DNA binding
    		•  1.92481088182068 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.9016235206634 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • actin binding
    		•  1.87817875565699 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.85015570449703 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.81145713371725 bayes_pls_golite062009
  • kinase activity
    		•  1.78069536883109 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.76912259507409 bayes_pls_golite062009
  • telethonin binding
    		•  1.75733591474207 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  1.66976264488423 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • hormone receptor binding
    		•  1.6360101685316 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • JUN kinase kinase kinase activity
    		•  1.60259443694567 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.59739467025045 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.59474164216385 bayes_pls_golite062009
  • growth factor binding
    		•  1.53863828216563 bayes_pls_golite062009
  • receptor binding
    		•  1.52843393025918 bayes_pls_golite062009
  • protein kinase activity
    		•  1.4654611643382 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  1.42275431028856 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  1.34841233233438 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  1.33825339298024 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  1.24312972088703 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22542472051838 bayes_pls_golite062009
  • transferase activity
    		•  1.19152443245584 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.16995153203536 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.14496167267281 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine kinase activity
    		•  1.11664317075762 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  1.10045286406485 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  1.10045286406485 bayes_pls_golite062009
  • cation channel activity
    		•  1.04999722123563 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  1.03605423743048 bayes_pls_golite062009
  • transcription activator activity
    		•  0.997272622653026 bayes_pls_golite062009
  • PTB domain binding
    		•  0.9900774724568 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.925299895386908 bayes_pls_golite062009
  • alpha-actinin binding
    		•  0.877087652539674 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.870666814073948 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • actin filament binding
    		•  0.794152600084 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.75189004129952 bayes_pls_golite062009
  • cytokine receptor binding
    		•  0.74933780353524 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • beta-catenin binding
    		•  0.693246095477001 bayes_pls_golite062009
  • protein complex binding
    		•  0.65988681496356 bayes_pls_golite062009
  • protein phosphorylated amino acid binding
    		•  0.649814096718101 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • JUN kinase kinase kinase kinase activity
    		•  0.546647574638943 bayes_pls_golite062009
  • hydrolase activity
    		•  0.539213162060111 bayes_pls_golite062009
  • cyclin-dependent protein kinase activating kinase activity
    		•  0.529121666062889 bayes_pls_golite062009
  • activin binding
    		•  0.510364757301021 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  0.505233004492768 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.456661966897198 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.41587987561486 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  0.406297251827056 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.401250804041384 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.399773397398032 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • JUN kinase kinase activity
    		•  0.332372116912461 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.318153468064373 bayes_pls_golite062009
  • phosphotyrosine binding
    		•  0.311079584914389 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.29798436765753 bayes_pls_golite062009
  • channel activity
    		•  0.287189255116606 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.287189255116606 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.261869836686301 bayes_pls_golite062009
  • RNA binding
    		•  0.245748631571068 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.242965929129671 bayes_pls_golite062009
  • ion channel activity
    		•  0.241519346930618 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  0.240883589532225 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.237134032032089 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.206747304356052 bayes_pls_golite062009
  • ligase activity
    		•  0.174357409093335 bayes_pls_golite062009
  • phosphoprotein binding
    		•  0.16798254471727 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.149958560815481 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.149958560815481 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.14842991990838 bayes_pls_golite062009
  • kinase binding
    		•  0.131981353175621 bayes_pls_golite062009
  • peptide binding
    		•  0.118578378753757 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.10704587503284 bayes_pls_golite062009
  • brain-derived neurotrophic factor binding
    		•  0.0794053647730006 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.0443241110585009 bayes_pls_golite062009
  • nitric-oxide synthase regulator activity
    		•  0.00407218246327123 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle