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Protein Overview: SAP155

General Information:
Name(s) found: SAP155 / YFR040W [SGD]
Description(s) found:
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  • gi|93141308|sp|P43612.3|SA155_YEAST RecName: Full=SIT4-associating protein SAP155 [NCBI NR]
  • gi|37362647|ref|NP_116698.2| Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p; Sap155p [Saccharomyces cerevisiae] [NCBI NR]
  • SIT4-associating protein SAP155 OS=Saccharomyces cerevisiae GN=SAP155 PE=1 SV=3 [Swiss-Prot]
  • SAP155 Sit4p-associated protein [mips]
  • Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p [SGD]
  • Chr VI from 234230-237238 [yeastorf5.fasta]
  • SAP155 SGDID:S0001936, Chr VI from 234229-237237, Verified ORF [yeastflysequest.fasta]
  • Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
  • SAP155 SGDID:S000001936, Chr VI from 234229-237237, Verified ORF, "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p; Sap155p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • SIT4-associating protein SAP155 [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1002 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IPILink to PubMed article]
    Biological Process: G1/S transition of mitotic cell cycle [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: protein serine/threonine phosphatase activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFWPFGQNL NHSNINKILD EYFHVLHELE RINPSVGKAI PAIFNNVQER GTSDSLDSIP  60
   61 EEYSHGDEVK TARGDQKSRF EKDDQQERYE KEEEERSMNS SESSTTSFSS GSTSKTDLDE 120
  121 EDISNATAPM MVTTKNLDNS FIERMLVETE LLNELSRQNK TLLDFICFGF FFDKKTNKKV 180
  181 NNMEYLVDQL MECISKIKTA TTVDLNNLID YQEQQQLDDS SQEDVYVESD TEQEEEKEDD 240
  241 NNSNNKKRRK RGSSSFGNDD INNNDDDDDA NEDDESAYLT KATIISEIFS LDIWLISESL 300
  301 VKNQSYLNKI WSIINQPNFN SENSPLVPIF LKINQNLLLT RQDQYLNFIR TERSFVDDML 360
  361 KHVDISLLMD FFLKIISTDK IESPTGIIEL VYDQNLISKC LSFLNNKESP ADIQACVGDF 420
  421 LKALIAISAN APLDDISIGP NSLTRQLASP ESIAKLVDIM INQRGAALNT TVSIVIELIR 480
  481 KNNSDYDQVN LLTTTIKTHP PSNRDPIYLG YLLRKFSNHL SDFFQIILDI ENDANIPLHE 540
  541 NQLHEKFKPL GFERFKVVEL IAELLHCSNM GLMNSKRAER IARRRDKVRS QLSHHLQDAL 600
  601 NDLSIEEKEQ LKTKHSPTRD TDHDLKNNNG KIDNDNNDND DESDYGDEID ESFEIPYINM 660
  661 KQTIKLRTDP TVGDLFKIKL YDTRIVSKIM ELFLTHPWNN FWHNVIFDII QQIFNGRMDF 720
  721 SYNSFLVLSL FNLKSSYQFM TDIVISDEKG TDVSRFSPVI RDPNFDFKIT TDFILRGYQD 780
  781 SYKFYELRKM NLGYMGHIVL IAEEVVKFSK LYKVELISPD IQVILQTEEW QYYSEEVLNE 840
  841 TRMMYSKILG GGSYIDDGNG NIIPQLPDNT TVLTPNGDAS NNNEILDSDT GSSNGTSGGG 900
  901 QLINVESLEE QLSLSTESDL HNKLREMLIN RAQEDVDNKN TENGVFILGP PEDKNSNSNI 960
  961 NNTNHNSNNS NNNDNNDNND NDNDNTRNYN EDADNDNDYD HE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ATG18 SAP155 SAP190 SIT4
    View Details Krogan NJ, et al. (2006) HRT3 PPZ2 SAP155 SDS24 SIT4
    View Details Gavin AC, et al. (2002) ACC1 AVT4 BEM2 CCT2 CDC25 FAB1 HRK1 MDS3 MIA40 MRPL3 SAP155 SAP185 SAP190 SIT4 SWT21
    View Details Ho Y, et al. (2002) ACC1 ADO1 ARP2 ATG18 ATG2 ATG20 ATP3 BGL2 CCT6 CDC55 FAA1 FAA4 GLT1 GSF2 HXT5 MAE1 NDE1 NPA3 PFK2 RMT2 RNR2 RPT4 SAP155 SAP185 SAP190 SIT4 TAP42 THI21 TIP41 UTP13 YMR196W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SAP155 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] deduced N/A No confident structure predictions are available.
    2 View Details [200..378] MSA 2.03997 View MSA. No confident structure predictions are available.
    3 View Details [379..589] deduced N/A No confident structure predictions are available.
    4 View Details [590..693] deduced N/A No confident structure predictions are available.
    5 View Details [694..764] deduced N/A No confident structure predictions are available.
    6 View Details [765..1002] MSA 1.015972 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle