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Protein Overview: AVT4

General Information:
Name(s) found: AVT4 / YNL101W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 713 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IMPLink to PubMed article]
    vacuole [IDALink to PubMed article]
    Biological Process: vacuolar transport [IGILink to PubMed article][IMPLink to PubMed article]
    amino acid transport [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: L-isoleucine transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]
    L-glutamine transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]
    transporter activity [ISSLink to PubMed article]
    L-tyrosine transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTNNGDGEH LGIRRNGNLR HPSNNMKIPR RAQSTVLNSN PFYSRKYSMS TLTPRDICRS  60
   61 VDSRVFVDMS SPNFQTLEDP HRDEIINSVR LNYLNSSKRS SVSHGNEAIP RVNPTKNSSA 120
  121 STIAAANVDS DDDETNLSSA GGDITHDIYK LVKAEDPKRL RRPRSMENVT PKIEHHTKLS 180
  181 SASGLNVPGG FRREFIVNKK RQEHQLNDSA SSDFTSHESD SINQSSPSSN QDIDKVPFLT 240
  241 RNFLEFLYVF GHFAGESFED DFIPDSSNMM IRGEDERSAL LSRPDHMKVL PSAKGTTSTK 300
  301 KVFLILLKSF IGTGVLFLPN AFHNGGLFFS VSMLAFFGIY SYWCYYILVQ AKSSCGVSSF 360
  361 GDIGLKLYGP WMRIIILFSL VITQVGFSGA YMIFTAKNLQ AFLDNVFHVG VLPLSYLMVF 420
  421 QTIIFIPLSF IRNISKLSLP SLLANFFIMA GLVIVIIFTA KRLFFDLMGT PAMGVVYGLN 480
  481 ADRWTLFIGT AIFAFEGIGL IIPVQDSMRN PEKFPLVLAL VILTATILFI SIATLGYLAY 540
  541 GSNVQTVILL NLPQSNIFVN LIQLFYSIAI MLSTPLQLFP AIKIIENKFF PKFTKIYVKH 600
  601 DDLTTRVELR PNSGKLNWKI KWLKNFIRSI IVIIVVSIAY FGSDNLDKFV SVIGSLACIP 660
  661 LVYIYPSMLH LRGNSLPETK GEFWRFKPML DTILIFFGIA SMLYTSYQSI FGV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) ACC1 AVT4 BEM2 CCT2 CDC25 FAB1 HRK1 MDS3 MIA40 MRPL3 SAP155 SAP185 SAP190 SIT4 SWT21
    View Details Qiu et al. (2008) AGP2 AVT1 AVT3 AVT4 AVT6 GAP1 TPO3 UGA4 VBA1 VBA2 VMA9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 sample 3928 - Asf1-S-TEV-ZZ (in hir3delta mutant) Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] deduced N/A No confident structure predictions are available.
    2 View Details [235..713] Pfam 152.638272 Transmembrane amino acid transporter protein No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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