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Protein Overview: VBA2

General Information:
Name(s) found: VBA2 / YBR293W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Permease of basic amino acids in the vacuolar membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    Biological Process: epidermal cell fate specification [IDALink to PubMed article][IMPLink to PubMed article]
    basic amino acid transport [IMPLink to PubMed article]
    Molecular Function: basic amino acid transmembrane transporter activity [IDA][IMP]
    drug transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISNWITTA YLITSTSFQP LYGSFSDALG RRNCLFFANG AFTIGCLACG FSKNIYMLSF  60
   61 MRALTGIGGG GLITLSTIVN SDVIPSSKRG IFQAFQNLLL GFGAICGASF GGTIASSIGW 120
  121 RWCFLIQVPI SVISSILMNY YVPNQKEYNR QNSSIFQNPG KILRDIDVMG SILIITGLTL 180
  181 QLLYLSLGCS TSKLSWTSPS VLLLLVGSVI ILLLFILHER KTSARAIIPM ELVNSSYSVV 240
  241 VLSISILVGF ASYAYLFTLP LFFQIVLGDS TAKAGLRLTI PSLFTPVGSL ITGFSMSKYN 300
  301 CLRLLLYIGI SLMFLGNFLF LFIEKTSPNW LIGLFLIPAN LGQGITFPTT LFTFIFMFSK 360
  361 SDQATATSTL YLFRSIGSVW GVAISAGVIQ LSFAGLLRSN LKGLLDENKI KKLIVQLSAN 420
  421 SSYIGSLHGE VKNTVIKSFD EATKRAHLMS TLLSSLALIL CILKDNLAKP KTRR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGP2 AVT1 AVT3 AVT4 BPT1 GAP1 TPO3 VBA1 VBA2 VBA3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] PSI-BLAST 6.09691 No description for 1lviA_ was found.
    2 View Details [192..404] MSA 16.007997 View MSA. No confident structure predictions are available.
    3 View Details [405..474] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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