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Protein Overview: HXT5

General Information:
Name(s) found: HXT5 / YHR096C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 592 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: hexose transport [IGILink to PubMed article]
    Molecular Function: fructose transmembrane transporter activity [IGILink to PubMed article]
    glucose transmembrane transporter activity [IDALink to PubMed article][IGILink to PubMed article]
    mannose transmembrane transporter activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELENAHQG PLEGSATVST NSNSYNEKSG NSTAPGTAGY NDNLAQAKPV SSYISHEGPP  60
   61 KDELEELQKE VDKQLEKKSK SDLLFVSVCC LMVAFGGFVF GWDTGTISGF VRQTDFIRRF 120
  121 GSTRANGTTY LSDVRTGLMV SIFNIGCAIG GIVLSKLGDM YGRKIGLMTV VVIYSIGIII 180
  181 QIASIDKWYQ YFIGRIISGL GVGGITVLAP MLISEVSPKQ LRGTLVSCYQ LMITFGIFLG 240
  241 YCTNFGTKNY SNSVQWRVPL GLCFAWSIFM IVGMTFVPES PRYLVEVGKI EEAKRSLARA 300
  301 NKTTEDSPLV TLEMENYQSS IEAERLAGSA SWGELVTGKP QMFRRTLMGM MIQSLQQLTG 360
  361 DNYFFYYGTT IFQAVGLEDS FETAIVLGVV NFVSTFFSLY TVDRFGRRNC LLWGCVGMIC 420
  421 CYVVYASVGV TRLWPNGQDQ PSSKGAGNCM IVFACFYIFC FATTWAPVAY VLISESYPLR 480
  481 VRGKAMSIAS ACNWIWGFLI SFFTPFITSA INFYYGYVFM GCMVFAYFYV FFFVPETKGL 540
  541 TLEEVNEMYE ENVLPWKSTK WIPPSRRTTD YDLDATRNDP RPFYKRMFTK EK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ATP3 HXT5 SAP155 SAP190 SIT4 TAP42
    View Details Qiu et al. (2008) HXT10 HXT5 HXT8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..58] deduced N/A No confident structure predictions are available.
    2 View Details [59..278]
    [324..538]    		 PSI-BLAST 476.218487 No description for 1ja5A_ was found.
    3 View Details [279..323]
    [539..592]    		 PSI-BLAST 476.218487 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • glycerol transmembrane transporter activity
    		•  7.11654923455995 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • glycerol-3-phosphate transmembrane transporter activity
    		•  5.74077413704789 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar binding
    		•  0.285073104957756 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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