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View Structure Prediction Details

Protein: HXT5
Organism: Saccharomyces cerevisiae
Length: 592 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXT5.

Description E-value Query
Range		 Subject
Range
HXT5_YEAST - Probable glucose transporter HXT5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HXT5 P...
HXT5 - Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable ca...
gi|190405875 - gi|190405875|gb|EDV09142.1| low-affinity glucose transporter [Saccharomyces cerevisiae RM11-1a]
gi|151944042 - gi|151944042|gb|EDN62335.1| hexose transporter [Saccharomyces cerevisiae YJM789]
 0.0 [1..592] [1..592]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 0.0 [1..587] [1..565]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [28..591] [9..570]

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Predicted Domain #1
Region A:
Residues: [1-58] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELENAHQG PLEGSATVST NSNSYNEKSG NSTAPGTAGY NDNLAQAKPV SSYISHEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [59-278] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPKDELEELQ KEVDKQLEKK SKSDLLFVSV CCLMVAFGGF VFGWDTGTIS GFVRQTDFIR  60
   61 RFGSTRANGT TYLSDVRTGL MVSIFNIGCA IGGIVLSKLG DMYGRKIGLM TVVVIYSIGI 120
  121 IIQIASIDKW YQYFIGRIIS GLGVGGITVL APMLISEVSP KQLRGTLVSC YQLMITFGIF 180
  181 LGYCTNFGTK NYSNSVQWRV PLGLCFAWSI FMIVGMTFVP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [324-538] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERLAGSASWG ELVTGKPQMF RRTLMGMMIQ SLQQLTGDNY FFYYGTTIFQ AVGLEDSFET  60
   61 AIVLGVVNFV STFFSLYTVD RFGRRNCLLW GCVGMICCYV VYASVGVTRL WPNGQDQPSS 120
  121 KGAGNCMIVF ACFYIFCFAT TWAPVAYVLI SESYPLRVRG KAMSIASACN WIWGFLISFF 180
  181 TPFITSAINF YYGYVFMGCM VFAYFYVFFF VPETK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 476.218487
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar binding 0.285073104957756 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [279-323] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPRYLVEVG KIEEAKRSLA RANKTTEDSP LVTLEMENYQ SSIEA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [539-592] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLTLEEVNEM YEENVLPWKS TKWIPPSRRT TDYDLDATRN DPRPFYKRMF TKEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 476.218487
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle