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Protein Overview: DPM1

General Information:
Name(s) found: DPM1 / YPR183W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 267 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    nuclear membrane-endoplasmic reticulum network [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article]
    protein amino acid O-linked glycosylation [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: transferase activity, transferring glycosyl groups [ISSLink to PubMed article]
    dolichyl-phosphate beta-D-mannosyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIEYSVIVP AYHEKLNIKP LTTRLFAGMS PEMAKKTELI FVDDNSQDGS VEEVDALAHQ  60
   61 GYNVRIIVRT NERGLSSAVL KGFYEAKGQY LVCMDADLQH PPETVPKLFE SLHDHAFTLG 120
  121 TRYAPGVGID KDWPMYRRVI SSTARMMARP LTIASDPMSG FFGLQKKYLE NCNPRDINSQ 180
  181 GFKIALELLA KLPLPRDPRV AIGEVPFTFG VRTEGESKLS GKVIIQYLQQ LKELYVFKFG 240
  241 ANNLILFITF WSILFFYVCY QLYHLVF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ACC1 ADK1 ATP3 ATP5 ATP7 CDC14 DMC1 DPM1 FUR1 GLC7 HEF3 HMS1 MCR1 MDJ1 NOP14 RVB2 SNF4 SPE3 SSZ1 TPS1 TRP3 TSA2 VAS1
    View Details Qiu et al. (2008) DPM1 PMT1 PMT2 STT3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIA40 No Comments Hazbun TR, et al. (2003)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DPM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] PSI-BLAST 10.39794 Spore coat polysaccharide biosynthesis protein SpsA
    2 View Details [126..267] MSA 5.579997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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