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Protein Overview: MSE1

General Information:
Name(s) found: MSE1 / YOL033W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: glutamyl-tRNA aminoacylation [IMPLink to PubMed article]
    translation [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: glutamate-tRNA ligase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMLRIPTRS YCSPSKLIKG VGLSPLKKSL LSKKIKEDIH PSLPVRTRFA PSPTGFLHLG  60
   61 SLRTALYNYL LARNTNGQFL LRLEDTDQKR LIEGAEENIY EILKWCNINY DETPIKQSER 120
  121 KLIYDKYVKI LLSSGKAYRC FCSKERLNDL RHSAMELKPP SMASYDRCCA HLGEEEIKSK 180
  181 LAQGIPFTVR FKSPERYPTF TDLLHGQINL QPQVNFNDKR YDDLILVKSD KLPTYHLANV 240
  241 VDDHLMGITH VIRGEEWLPS TPKHIALYNA FGWACPKFIH IPLLTTVGDK KLSKRKGDMS 300
  301 ISDLKRQGVL PEALINFCAL FGWSPPRDLA SKKHECFSME ELETIFNLNG LTKGNAKVDD 360
  361 KKLWFFNKHF LQKRILNPST LRELVDDIMP SLESIYNTST ISREKVAKIL LNCGGSLSRI 420
  421 NDFHDEFYYF FEKPKYNDND AVTKFLSKNE SRHIAHLLKK LGQFQEGTDA QEVESMVETM 480
  481 YYENGFSRKV TYQAMRFALA GCHPGAKIAA MIDILGIKES NKRLSEGLQF LQREKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALG5 BRE5 CSN12 CUP2 DBP7 LUG1 MET10 MSC7 MSE1 NOP53 NPY1 PBP4 RPF2 RRS1 SAS5 UME6 YGR126W YHR127W YPR045C YRA1
    View Details Ho Y, et al. (2002) ARP7 DIG1 DIG2 FET4 GFA1 GUS1 HAS1 HXT6 KSS1 MKT1 MSE1 NAP1 PHO84 PIM1 PMA1 PYC1 RGC1 RPA135 RPN10 SEN1 STE12 STE7 TEC1 UBI4 YDR239C YHR033W
    View Details Qiu et al. (2008) MSE1 NAM2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3829 - low filter Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MSE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..282] PSI-BLAST 780.218487 C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
    2 View Details [283..368] PSI-BLAST 780.218487 C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
    3 View Details [369..429] PSI-BLAST 780.218487 C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
    4 View Details [430..536] PSI-BLAST 780.218487 C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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