YRC Public Data Repository - Protein Structure Prediction

Protein:	MSE1
Organism:	Saccharomyces cerevisiae
Length:	536 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSE1.

Description	E-value	Query Range	Subject Range
gi\|151945598 - gi\|151945598\|gb\|EDN63839.1\| mitochodrial glutamyl-tRNA synthetase [Saccharomyces cerevisiae YJM789] SYEM_YEAST - Glutamate--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MS... gi\|190407310 - gi\|190407310\|gb\|EDV10577.1\| glutamine-tRNA ligase [Saccharomyces cerevisiae RM11-1a] MSE1 - Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated	0.0	[1..536]	[1..536]
gi\|253978457, gi... - gi\|254289150\|ref\|YP_003054898.1\| glutamyl-tRNA synthetase [Escherichia coli BL21(DE3)], gi\|253978457... gi\|254162389, gi... - gi\|254162389\|ref\|YP_003045497.1\| glutamyl-tRNA synthetase [Escherichia coli B str. REL606], gi\|25397... SYE_ECOLI - Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase) (GluRS) - Escherichia coli SYE_ECOSE - Glutamate--tRNA ligase OS=Escherichia coli (strain SE11) GN=gltX PE=3 SV=1 SYE_ECODH - Glutamate--tRNA ligase OS=Escherichia coli (strain K12 / DH10B) GN=gltX PE=3 SV=1 gi\|218696039, gi... - gi\|218696039\|ref\|YP_002403706.1\| glutamyl-tRNA synthetase [Escherichia coli 55989], gi\|218352771\|emb... EG10407 - glutamyl-tRNA synthetase / Glutamate--tRNA ligase gi\|75515743, gi\|... - gi\|75515743\|ref\|ZP_00737878.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ... gi\|30042056, gi\|... - gi\|30063801\|ref\|NP_837972.1\| glutamyl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi\|30042056... gi\|75259838, gi\|... - gi\|75259838\|ref\|ZP_00731140.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ... gi\|1799814, gi\|8... - gi\|89109217\|ref\|AP_002997.1\| glutamyl-tRNA synthetase [Escherichia coli str. K-12 substr. W3110], gi... EG10407 - glutamyl-tRNA synthetase / Glutamate--tRNA ligase gi\|75210186 - gi\|75210186\|ref\|ZP_00710358.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ... SYE_ECOHS - Glutamate--tRNA ligase OS=Escherichia coli O9:H4 (strain HS) GN=gltX PE=3 SV=1 gi\|238861344, gi... - gi\|238901566\|ref\|YP_002927362.1\| glutamyl-tRNA synthetase [Escherichia coli BW2952], gi\|238861344\|gb... SYE_ECO24 - Glutamate--tRNA ligase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=gltX PE=3 SV=1 gi\|242378013, gi... - gi\|251785740\|ref\|YP_003000044.1\| hypothetical protein B21_02267 [Escherichia coli BL21], gi\|24237801...	0.0	[43..536]	[1..470]
gi\|208733378, gi... - gi\|208812101\|ref\|ZP_03253430.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|208819547, gi... - gi\|208819547\|ref\|ZP_03259867.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042], gi\|... SYE_ECO5E - Glutamate--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=gltX PE=3 SV=1 gi\|217320169, gi... - gi\|217327802\|ref\|ZP_03443885.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588], gi... gi\|188998418, gi... - gi\|188998418\|gb\|EDU67429.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|189372962, gi... - gi\|189372962\|gb\|EDU91378.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|16878... SYE_ECO57 - Glutamate--tRNA ligase OS=Escherichia coli O157:H7 GN=gltX PE=3 SV=1 gi\|195938752 - gi\|195938752\|ref\|ZP_03084134.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208806319, gi... - gi\|208806319\|ref\|ZP_03248656.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|189360235, gi... - gi\|189360235\|gb\|EDU78654.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|168772762, gi... - gi\|187771184\|gb\|EDU35028.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|13362748, gi\|... - gi\|15832532\|ref\|NP_311305.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|1336... gi\|15802940, gi\|... - gi\|15802940\|ref\|NP_288968.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi\|12516778... gi\|209764278, gi... - pir\|\|H85882 glutamate tRNA synthetase, catalytic subunit [imported] - Escherichia coli (strain O157:... gi\|254593760, gi... - gi\|254794360\|ref\|YP_003079197.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], g...	0.0	[43..536]	[1..470]
SYE_SALPB - Glutamate--tRNA ligase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=gltX PE=3 SV=1 SYE_SALPB - Glutamyl-tRNA synthetase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=gltX PE=3 SV=1 SYE_SALTY - Glutamate--tRNA ligase OS=Salmonella typhimurium GN=gltX PE=3 SV=1 SYE_SALTY - Glutamate--tRNA ligase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=gltX PE=3 ... SYE_SALTI - Glutamate--tRNA ligase OS=Salmonella typhi GN=gltX PE=3 SV=1 SYE_SALTI - Glutamyl-tRNA synthetase OS=Salmonella typhi GN=gltX PE=3 SV=1 gi\|29136590, gi\|... - gi\|29140965\|ref\|NP_804307.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar T... gi\|200386857, gi... - gi\|200386857\|ref\|ZP_03213469.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|238912833 - gi\|238912833\|ref\|ZP_04656670.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|197262511, gi... - gi\|197262511\|ref\|ZP_03162585.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... SYE_SALA4 - Glutamate--tRNA ligase OS=Salmonella agona (strain SL483) GN=gltX PE=3 SV=1 SYE_SALSV - Glutamate--tRNA ligase OS=Salmonella schwarzengrund (strain CVM19633) GN=gltX PE=3 SV=1 SYE_SALTY - Glutamyl-tRNA synthetase OS=Salmonella typhimurium GN=gltX PE=3 SV=1 gi\|214002831 - gi\|214002831\|ref\|ZP_03413566.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|205349554, gi... - gi\|205349554\|gb\|EDZ36185.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Ha... lcl\|NC_016856.1_... - [gene=gltX] [protein=glutamyl-tRNA synthetase] [protein_id=YP_005238501.1] [location=complement(2581... gi\|205338343, gi... - gi\|205338343\|gb\|EDZ25107.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar He... gi\|205331587, gi... - gi\|205331587\|gb\|EDZ18351.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Ke... gi\|205328804, gi... - gi\|205328804\|gb\|EDZ15568.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar 4,... gi\|194456083, gi... - gi\|194469719\|ref\|ZP_03075703.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... SYE_SALHS - Glutamate--tRNA ligase OS=Salmonella heidelberg (strain SL476) GN=gltX PE=3 SV=1 SYE_SALNS - Glutamate--tRNA ligase OS=Salmonella newport (strain SL254) GN=gltX PE=3 SV=1 gi\|168817838, gi... - gi\|205344830\|gb\|EDZ31594.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar We...	0.0	[43..536]	[1..470]
gi\|149291564, gi... - gi\|149365151\|ref\|ZP_01887186.1\| glutamyl-tRNA synthetase [Yersinia pestis CA88-4125], gi\|149291564\|g... SYE_YERPP - Glutamate--tRNA ligase OS=Yersinia pestis (strain Pestoides F) GN=gltX PE=3 SV=1 gi\|45437250, gi\|... - gi\|45442386\|ref\|NP_993925.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Microtus str. 91001], ... gi\|22125395, gi\|... - gi\|22125395\|ref\|NP_668818.1\| glutamyl-tRNA synthetase [Yersinia pestis KIM], gi\|21958280\|gb\|AAM85069... gi\|16123165, gi\|... - gi\|218930033\|ref\|YP_002347908.1\| glutamyl-tRNA synthetase [Yersinia pestis CO92], gi\|16123165\|ref\|NP... SYE_YERPG - Glutamate--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=gltX PE=3 SV=1 SYE_YERPE - Glutamate--tRNA ligase OS=Yersinia pestis GN=gltX PE=3 SV=1 gi\|229694941, gi... - gi\|229838575\|ref\|ZP_04458734.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. PEX... gi\|229895643, gi... - gi\|229895643\|ref\|ZP_04510814.1\| glutamyl-tRNA synthetase [Yersinia pestis Pestoides A], gi\|229701449... gi\|229899141, gi... - gi\|229899141\|ref\|ZP_04514284.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. Ind... gi\|165989927, gi... - gi\|166011249\|ref\|ZP_02232147.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. E19790... gi\|165926928, gi... - gi\|165926928\|ref\|ZP_02222760.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. F19... gi\|167398458, gi... - gi\|167398458\|ref\|ZP_02303982.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. UG05-0... gi\|166206452, gi... - gi\|166212521\|ref\|ZP_02238556.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Antiqua str. B42003... SYE_YERPA - Glutamate--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=gltX PE=3 SV=1 gi\|167424635, gi... - gi\|167424635\|ref\|ZP_02316388.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Mediaevalis str. K1... SYE_YERPN - Glutamate--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=gltX PE=3 SV=1 gi\|167421386, gi... - gi\|167421386\|ref\|ZP_02313139.1\| glutamyl-tRNA synthetase [Yersinia pestis biovar Orientalis str. MG0...	0.0	[43..536]	[1..470]
gi\|124115722, gi... - gi\|153213798\|ref\|ZP_01949006.1\| glutamyl-tRNA synthetase [Vibrio cholerae 1587], gi\|124115722\|gb\|EAY... gi\|227082338, gi... - gi\|227082338\|ref\|YP_002810889.1\| glutamyl-tRNA synthetase [Vibrio cholerae M66-2], gi\|227010226\|gb\|A... gi\|9656771, gi\|1... - gi\|9656771\|gb\|AAF95358.1\| glutamyl-tRNA synthetase [Vibrio cholerae O1 biovar El Tor str. N16961], g... gi\|121631029, gi... - gi\|121726576\|ref\|ZP_01679825.1\| glutamyl-tRNA synthetase [Vibrio cholerae V52], gi\|121631029\|gb\|EAX6... gi\|254849344, gi... - gi\|254849344\|ref\|ZP_05238694.1\| glutamyl-tRNA synthetase [Vibrio cholerae MO10], gi\|254845049\|gb\|EET... gi\|153221279, gi... - gi\|153221279\|ref\|ZP_01952294.1\| glutamyl-tRNA synthetase [Vibrio cholerae MAK 757], gi\|124119808\|gb\|... gi\|153820833, gi... - gi\|153820833\|ref\|ZP_01973500.1\| glutamyl-tRNA synthetase [Vibrio cholerae B33], gi\|126521625\|gb\|EAZ7... gi\|126512367, gi... - gi\|153817099\|ref\|ZP_01969766.1\| glutamyl-tRNA synthetase [Vibrio cholerae NCTC 8457], gi\|126512367\|g... gi\|11271642 - pir\|\|G82104 glutamyl-tRNA synthetase VC2214 [imported] - Vibrio cholerae (strain N16961 serogroup O1... gi\|254286477, gi... - gi\|254286477\|ref\|ZP_04961434.1\| glutamyl-tRNA synthetase [Vibrio cholerae AM-19226], gi\|197752001\|re... gi\|148875190, gi... - gi\|153829349\|ref\|ZP_01982016.1\| glutamyl-tRNA synthetase [Vibrio cholerae 623-39], gi\|148875190\|gb\|E... gi\|146316991, gi... - gi\|227118660\|ref\|YP_002820556.1\| glutamyl-tRNA synthetase [Vibrio cholerae O395], gi\|227014110\|gb\|AC...	0.0	[25..535]	[18..507]
SYE_PASMU - Glutamate--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=gltX PE=3 SV=1 SYE_PASMU - Glutamyl-tRNA synthetase OS=Pasteurella multocida GN=gltX PE=3 SV=1	0.0	[31..535]	[1..479]
SYE_HAEIN - Glutamyl-tRNA synthetase OS=Haemophilus influenzae GN=gltX PE=3 SV=1 gi\|145271030, gi... - gi\|145639812\|ref\|ZP_01795413.1\| glutamyl-tRNA synthetase [Haemophilus influenzae PittII], gi\|1452710... gi\|53733176 - gi\|53733176\|ref\|ZP_00156113.2\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Haemophilus influ... SYE_HAEIN - Glutamate--tRNA ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=gltX...	0.0	[31..535]	[1..479]
gi\|16761339 - gi\|16761339\|ref\|NP_456956.1\| glutamyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar T... gi\|16503638, gi\|... - gi\|25293265\|pir\|\|AI0808 glutamate-tRNA ligase (EC 6.1.1.17) - Salmonella enterica subsp. enterica se...	0.0	[43..501]	[1..434]

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Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMLRIPTRS YCSPSKLIKG VGLSPLKKSL LSKKIKEDIH PSLPVRTRFA PSPTGFLHLG  60
   61 SLRTALYNYL LARNTNGQFL LRLEDTDQKR LIEGAEENIY EILKWCNINY DETPIKQSER 120
  121 KLIYDKYVKI LLSSGKAYRC FCSKERLNDL RHSAMELKPP SMASYDRCCA HLGEEEIKSK 180
  181 LAQGIPFTVR FKSPERYPTF TDLLHGQINL QPQVNFNDKR YDDLILVKSD KLPTYHLANV 240
  241 VDDHLMGITH VIRGEEWLPS TPKHIALYNA FGWACPKFIH IP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	780.218487
Match:	1gln__
Description:	C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [283-368]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLTTVGDKKL SKRKGDMSIS DLKRQGVLPE ALINFCALFG WSPPRDLASK KHECFSMEEL  60
   61 ETIFNLNGLT KGNAKVDDKK LWFFNK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	780.218487
Match:	1gln__
Description:	C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [369-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HFLQKRILNP STLRELVDDI MPSLESIYNT STISREKVAK ILLNCGGSLS RINDFHDEFY  60
   61 Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	780.218487
Match:	1gln__
Description:	C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [430-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FFEKPKYNDN DAVTKFLSKN ESRHIAHLLK KLGQFQEGTD AQEVESMVET MYYENGFSRK  60
   61 VTYQAMRFAL AGCHPGAKIA AMIDILGIKE SNKRLSEGLQ FLQREKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	780.218487
Match:	1gln__
Description:	C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits