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Protein Overview: RPC37

General Information:
Name(s) found: RPC37 / YKR025W [SGD]
Description(s) found:
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  • gi|6322877|ref|NP_012950.1| RNA polymerase III subunit C37; Rpc37p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|549598|sp|P36121.1|RPC5_YEAST RecName: Full=DNA-directed RNA polymerase III subunit RPC5; Short=RNA polymerase III subunit C5; AltName: Full=DNA-directed RNA polymerase III 37 kDa polypeptide; AltName: Full=RNA polymerase III subunit C37 [NCBI NR]
  • pir||S38094 hypothetical protein YKR025w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|51013223|gb|AAT92905.1| YKR025W [Saccharomyces cerevisiae] [NCBI NR]
  • gi|486451|emb|CAA82097.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • (P36121) Hypothetical 32.1 kDa protein in DBP7-GCN3 intergenic region [Swiss-Prot]
  • DNA-directed RNA polymerase III subunit RPC5 OS=Saccharomyces cerevisiae GN=RPC37 PE=1 SV=1 [Swiss-Prot]
  • DNA-directed RNA polymerase III 37 kDa polypeptide (EC 2.7.7.6) (C37) (RNA polymerase C subunit 5) (RPC5) - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • RPC37 Pol III transcription [mips]
  • RNA polymerase III subunit C37 [SGD]
  • RPC37, Chr XI from 487408-488256 [yeast_orfs2]
  • Chr XI from 487408-488256 [yeastorf3.fasta]
  • RPC37 SGDID:S0001733, Chr XI from 487413-488261, Verified ORF [yeastflysequest.fasta]
  • RNA polymerase III subunit C37 [Saccharomyces cerevisiae]gi|51013223|gb|AAT92905.1| YKR025W [Saccharomyces cerevisiae]gi|486451|emb|CAA82097.1| unnamed protein product [Saccharomyces cerevisiae]gi|539242|pir||S38094 hypothetical protein YKR025w - yeast [nrdb_11152004_Chlamydomonas]
  • RPC37 SGDID:S000001733, Chr XI from 487413-488261, Verified ORF, "RNA polymerase III subunit C37" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • RNA polymerase III subunit C37; Rpc37p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Hypothetical 32.1 kDa protein in DBP7-GCN3 intergenic region [nr-271106-contam.fasta]
  • YKR025W [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • DNA-directed RNA polymerase III subunit RPC5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPC37 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RPC37 SGDID:S000001733, Chr XI from 487770-488618, Genome Release 64-1-1, Verified ORF, "RNA polymerase III subunit C37" [yeast-030211-contam.fasta]
  • RPC37 SGDID:S000001733, Chr XI from 487770-488618, Genome Release 64-2-1, Verified ORF, "RNA polymerase III subunit C37" [20141208_orf_trans.fasta]
  • YKR025W SGDID:S000001733, Chr XI from 487770-488618, Genome Release 64-1-1, Verified ORF, "RNA polymerase III subunit C37" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 282 amino acids

    Gene Ontology:
    Cellular Component: DNA-directed RNA polymerase III complex [TASLink to PubMed article]
    Biological Process: transcription from RNA polymerase III promoter [TAS]
    Molecular Function: DNA-directed RNA polymerase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDNKLFVT EEDEEDRTQD RADVEDESND IDMIADENGT NSAIANEQEE KSEEVKAEDD  60
   61 TGEEEEDDPV IEEFPLKISG EEESLHVFQY ANRPRLVGRK PAEHPFISAA RYKPKSHLWE 120
  121 IDIPLDEQAF YNKDKAESEW NGVNVQTLKG VGVENNGQYA AFVKDMQVYL VPIERVAQLK 180
  181 PFFKYIDDAN VTRKQEDARR NPNPSSQRAQ VVTMSVKSVN DPSQNRLTGS LLAHKVADEE 240
  241 ANIELTWAEG TFEQFKDTIV KEAEDKTLVA LEKQEDYIDN LV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) MAF1 RET1 RPB10 RPB5 RPB8 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO26 RPO31
    View Details Krogan NJ, et al. (2006) BDP1 CDC14 COY1 FAR7 MAF1 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPC10 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO31 YDL144C YIR024C
    View Details Gavin AC, et al. (2006) RET1 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO31
    View Details Gavin AC, et al. (2002) AMS1 ASC1 CDC14 DHH1 FBA1 MAF1 RET1 RPA12 RPA135 RPA190 RPA43 RPA49 RPB10 RPB5 RPB8 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO26 RPO31 RSC8 SRO7
    View Details Qiu et al. (2008) RET1 RPA12 RPA190 RPA43 RPB10 RPB11 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RPC37 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..282] MSA 3.009961 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle