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Protein Overview: QCR8

General Information:
Name(s) found: QCR8 / YJL166W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 94 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial respiratory chain complex III [IDALink to PubMed article]
    Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c [IMPLink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: ubiquinol-cytochrome-c reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPPSGKTYM GWWGHMGGPK QKGITSYAVS PYAQKPLQGI FHNAVFNSFR RFKSQFLYVL  60
   61 IPAGIYWYWW KNGNEYNEFL YSKAGREELE RVNV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) COB COR1 CYT1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1
    View Details Qiu et al. (2008) AAC1 ATP1 ATP14 ATP15 ATP16 ATP17 ATP18 ATP19 ATP2 ATP20 ATP3 ATP4 ATP5 ATP6 ATP7 ATP8 COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYB2 CYC7 CYT1 DLD1 INH1 MCR1 OLI1 POR1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4 STF2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CHL4 QCR8 1 Unpublished Fields Lab Data
    View Screen CTF13 QCR8 1 Unpublished Fields Lab Data
    View Screen RRB1 QCR8 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data QCR8 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] PSI-BLAST 463.29073 Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  11.4657297014599 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  11.4657297014599 bayes_pls_golite062009
  • ubiquinone binding
    		•  8.14330726546719 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  8.07004376323578 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  5.53710572481351 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  5.38577566963514 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.79259194111116 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.78909275746755 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.5536689474984 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.36122531415799 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.96296151827022 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.77517262558965 bayes_pls_golite062009
  • quinone binding
    		•  2.82234066289866 bayes_pls_golite062009
  • binding
    		•  1.40610802203062 bayes_pls_golite062009
  • cofactor binding
    		•  0.937113949001792 bayes_pls_golite062009
  • catalytic activity
    		•  0.442357802307605 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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