YRC Public Data Repository - Protein Structure Prediction

Protein:	QCR8
Organism:	Saccharomyces cerevisiae
Length:	94 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QCR8.

Description	E-value	Query Range	Subject Range
ORFP:11940 - YJL166W, Contig c343 91796-92080 reverse complement QCR8_YEAST - Cytochrome b-c1 complex subunit 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QCR8 P... gi\|190409345 - gi\|190409345\|gb\|EDV12610.1\| ubiquinol cytochrome C reductase subunit 8 [Saccharomyces cerevisiae RM1... gi\|151944963 - gi\|151944963\|gb\|EDN63218.1\| ubiquinol-cytochrome c oxidoreductase complex subunit [Saccharomyces cer... QCR8 - Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inn...	4.0E-36	[1..94]	[1..94]
UCRQ_KLULA, QCR8... - Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C - Kluyveromyces lactis (Yea... QCR8_KLULA - Cytochrome b-c1 complex subunit 8 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 /...	2.0E-34	[1..94]	[1..94]
qcr8 - ubiquinol-cytochrome-c reductase complex subunit 7 QCR8_SCHPO - Cytochrome b-c1 complex subunit 8 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=qcr8 PE=...	7.0E-34	[2..90]	[3..91]
QCR8_NEUCR - Cytochrome b-c1 complex subunit 8 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 ... UCRQ_NEUCR, QCR8... - Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C precursor - Neurospora cras...	2.0E-29	[2..88]	[13..101]
QCR8_BOVIN - Cytochrome b-c1 complex subunit 8 OS=Bos taurus GN=UQCRQ PE=1 SV=3	1.0E-22	[13..83]	[5..71]
gi\|3659967, gi\|5... - gi\|5822457\|pdb\|2BCC\|A Chain A, Stigmatellin-Bound Cytochrome Bc1 Complex From Chicken, gi\|3660376\|pd...	4.0E-22	[13..83]	[4..70]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-22	[13..83]	[4..70]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPPSGKTYM GWWGHMGGPK QKGITSYAVS PYAQKPLQGI FHNAVFNSFR RFKSQFLYVL  60
   61 IPAGIYWYWW KNGNEYNEFL YSKAGREELE RVNV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	463.29073
Match:	1ezvG_
Description:	Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquinol-cytochrome-c reductase activity	11.4657297014599	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	11.4657297014599	bayes_pls_golite062009
ubiquinone binding	8.14330726546719	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	8.07004376323578	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	5.53710572481351	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	5.38577566963514	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	4.79259194111116	bayes_pls_golite062009
oxidoreductase activity	4.78909275746755	bayes_pls_golite062009
cation transmembrane transporter activity	4.5536689474984	bayes_pls_golite062009
ion transmembrane transporter activity	4.36122531415799	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.96296151827022	bayes_pls_golite062009
substrate-specific transporter activity	3.77517262558965	bayes_pls_golite062009
quinone binding	2.82234066289866	bayes_pls_golite062009
binding	1.40610802203062	bayes_pls_golite062009
cofactor binding	0.937113949001792	bayes_pls_golite062009
catalytic activity	0.442357802307605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: