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Protein Overview: IRE1

Protein Complex Data

  PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
View Details Krogan NJ, et al. (2006) IRE1 LYS21

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run TID3 No Comments Cheeseman IM, et al. (2002)
View Run RPA135 No Comments Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

  BAIT PREY HITS PUBLICATION
View Screen IRE1 YDR532C 2 Uetz P, et al. (2000)

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data IRE1 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..471] ORFEUS 14.89 Methanol dehydrogenase, heavy chain
2 View Details [472..637] deduced N/A No confident structure predictions are available.
3 View Details [638..714]
[732..747]
PSI-BLAST 253.38764 Cyclin-dependent PK, CDK2
4 View Details [715..731]
[748..1060]
PSI-BLAST 253.38764 Cyclin-dependent PK, CDK2
5 View Details [1061..1115] deduced N/A No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2 No functions predicted.
3 No functions predicted.
4
Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
  • 5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
  • 5.4586557943719 bayes_pls_golite062009
  • kinase activity
  • 5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 4.96052051118534 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
  • 4.62392503670521 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 4.46381887831481 bayes_pls_golite062009
  • transferase activity
  • 3.97138602499442 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 3.06466701648326 bayes_pls_golite062009
  • binding
  • 2.74863538127007 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
  • 2.41610417530517 bayes_pls_golite062009
  • protein binding
  • 2.276111749106 bayes_pls_golite062009
  • ATP binding
  • 1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 1.93596671856664 bayes_pls_golite062009
  • cation transmembrane transporter activity
  • 1.93176092222748 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 1.90928021591891 bayes_pls_golite062009
  • ion transmembrane transporter activity
  • 1.90354666768303 bayes_pls_golite062009
  • molecular transducer activity
  • 1.79921740914853 bayes_pls_golite062009
  • signal transducer activity
  • 1.79921740914853 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 1.71452519680794 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
  • 1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
  • 1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
  • 1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
  • 1.62657794525303 bayes_pls_golite062009
  • transcription regulator activity
  • 1.56748951434625 bayes_pls_golite062009
  • nucleic acid binding
  • 1.46547714006072 bayes_pls_golite062009
  • MAP kinase kinase activity
  • 1.42275431028856 bayes_pls_golite062009
  • protein tyrosine kinase activity
  • 1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
  • 1.38496328649031 bayes_pls_golite062009
  • DNA binding
  • 1.35333135345112 bayes_pls_golite062009
  • receptor signaling protein activity
  • 1.27291233344322 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
  • 1.27184436658773 bayes_pls_golite062009
  • insulin receptor activity
  • 1.22442673174261 bayes_pls_golite062009
  • catalytic activity
  • 1.21655087018101 bayes_pls_golite062009
  • transcription factor activity
  • 1.10928254946881 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
  • 1.01340572255694 bayes_pls_golite062009
  • transcription activator activity
  • 0.997272622653026 bayes_pls_golite062009
  • PTB domain binding
  • 0.9900774724568 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
  • 0.872782211382796 bayes_pls_golite062009
  • MAP kinase activity
  • 0.81943579965027 bayes_pls_golite062009
  • insulin binding
  • 0.614254468447749 bayes_pls_golite062009
  • transporter activity
  • 0.595111702412257 bayes_pls_golite062009
  • cyclin-dependent protein kinase activating kinase activity
  • 0.529121666062889 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
  • 0.48345772948903 bayes_pls_golite062009
  • fibroblast growth factor binding
  • 0.470448662251808 bayes_pls_golite062009
  • protein kinase C activity
  • 0.41587987561486 bayes_pls_golite062009
  • transmembrane transporter activity
  • 0.41384976209545 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
  • 0.401250804041384 bayes_pls_golite062009
  • magnesium ion binding
  • 0.393328812780268 bayes_pls_golite062009
  • telethonin binding
  • 0.386946764759301 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
  • 0.37115026509016 bayes_pls_golite062009
  • protein complex binding
  • 0.343240719858581 bayes_pls_golite062009
  • insulin receptor binding
  • 0.266450215230107 bayes_pls_golite062009
  • cation channel activity
  • 0.245400615103891 bayes_pls_golite062009
  • SH2 domain binding
  • 0.226760162354251 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.0922946791401962 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
  • 0.0556163711947139 bayes_pls_golite062009
  • transmembrane receptor activity
  • 0.00652065412910241 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0040394359628233 bayes_pls_golite062009
    5 No functions predicted.




    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle