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Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. Any process that modulates the frequency, rate or extent of protein kinase activity. Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating endoplasmic reticulum (ER) stress. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that activates or increases the frequency, rate or extent of protein kinase activity. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of signaling protein activity involved in unfolded protein response
Acc: GO:0006987
Aspect: Biological Process
Desc: The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.
Synonyms:
  • unfolded protein response, activation of signalling protein kinase/endonuclease
  • unfolded protein response, activation of signaling protein activity
  • unfolded protein response, activation of signaling protein kinase/endonuclease
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006987 - activation of signaling protein activity involved in unfolded protein response (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle