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Protein Overview: BUD32

General Information:
Name(s) found: BUD32 / YGR262C [SGD]
Description(s) found:
Found 35 descriptions.
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  • Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    EKC/KEOPS protein complex [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: cellular bud site selection [IMPLink to PubMed article]
    telomere maintenance [IGILink to PubMed article][IMPLink to PubMed article]
    protein amino acid phosphorylation [IDALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IPILink to PubMed article]
    Molecular Function: protein serine/threonine kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQEFIDKVS SYLTPDVDIA PISQGAEAIV FTTTTHPYLP RAKDSHQKYI IKYRPPKRYR  60
   61 HPQIDQALTK HRTLNESRLL AKLYLIPGLC VPQLIACDPY NGFIWLEFLG EDLPGGHGFS 120
  121 NLKNFLWMHD QDPYSDLVAT TLRKVGRQIG LLHWNDYCHG DLTSSNIVLV RDGARWTPHL 180
  181 IDFGLGSVSN LVEDKGVDLY VLERAILSTH SKHAEKYNAW IMEGFEEVYR EQGAKGAKKL 240
  241 KEVTKRFEEV RLRGRKRSML G

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BUD32 CGI121 GRX4
    View Details Krogan NJ, et al. (2006) BUD32 GRX4
    View Details Ho Y, et al. (2002) AAC3 BUD32 CAR2 CGI121 CPR6 CRM1 DIA4 GRX3 GRX4 HEF3 IDP2 IMD2 IMD4 KAE1 NPA3 PHO81 POR1 RNH202 RPN1 RPN5 RPN6 RPT1 RPT3 SEC18 SEC23 SGO1 TMA29 URA7 YHR033W
    View Details Qiu et al. (2008) BUD32 CGI121 PCC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen DMC1 BUD32 1 Unpublished Fields Lab Data
    View Screen RCY1 BUD32 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BUD32 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] PSI-BLAST 70.69897 Calmodulin-dependent protein kinase
    2 View Details [116..261] PSI-BLAST 70.69897 Calmodulin-dependent protein kinase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle