Protein Overview: EUG1

General Information:
Name(s) found:	EUG1 / YDR518W [SGD]
Description(s) found: Found 29 descriptions. SHOW ALL	Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER [SGD]
Organism:	Saccharomyces cerevisiae
Length:	517 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	protein folding [IGI]
Molecular Function:	protein disulfide isomerase activity [IDA][IGI][IMP][ISS] protein disulfide oxidoreductase activity [IDA][IGI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVTTRFISA IVSFCLFASF TLAENSARAT PGSDLLVLTE KKFKSFIESH PLVLVEFFAP  60
   61 WCLHSQILRP HLEEAASILK EHNVPVVQID CEANSMVCLQ QTINTYPTLK IFKNGRIFDG 120
  121 QVYRGVKITD EITQYMIQLY EASVIYLNSE DEIQPYLENA TLPVVINRGL TGLNETYQEV 180
  181 ALDLAEDYVF LSLLDSEDKS LSIHLPNTTE PILFDGNVDS LVGNSVALTQ WLKVVILPYF 240
  241 TDIEPDLFPK YISSNLPLAY FFYTSEEELE DYTDLFTQLG KENRGQINFI ALNSTMFPHH 300
  301 VRFLNMREQF PLFAIHNMIN NLKYGLPQLP EEEYAKLEKP QPLDRDMIVQ LVKDYREGTA 360
  361 KPIVKSEEIP KEQKSNVYKI VGKTHDDIVH DDDKDVLVKY YATWCIHSKR FAPIYEEIAN 420
  421 VLASDESVRD KILIAEVDSG ANDILSFPVT GYPTIALYPA GNNSKPIIFN KIRNLEDVFE 480
  481 FIKESGTHHI DGQAIYDKLH QAKDSEVSTE DTVHDEL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	EUG1	WHI2	2	Unpublished Fields Lab Data
View Screen	EUG1	SCD6	2	Unpublished Fields Lab Data
View Screen	EUG1	RPC53	2	Unpublished Fields Lab Data
View Screen	EUG1	CBS2	2	Unpublished Fields Lab Data
View Screen	EUG1	YBL112C, YHR218W-A	1	Unpublished Fields Lab Data
View Screen	EUG1	VPS64	1	Unpublished Fields Lab Data
View Screen	EUG1	HSP150	1	Unpublished Fields Lab Data
View Screen	EUG1	YNR004W	1	Unpublished Fields Lab Data
View Screen	EUG1	PAU24	1	Unpublished Fields Lab Data
View Screen	EUG1	EMI2	1	Unpublished Fields Lab Data
View Screen	EUG1	YJR008W	1	Unpublished Fields Lab Data
View Screen	EUG1	PDI1	1	Unpublished Fields Lab Data
View Screen	EUG1	PAB1	1	Unpublished Fields Lab Data
View Screen	EUG1	YKR017C	1	Unpublished Fields Lab Data
View Screen	EUG1	ENV7	1	Unpublished Fields Lab Data
View Screen	EUG1	KRR1	1	Unpublished Fields Lab Data
View Screen	EUG1	YER181C	1	Unpublished Fields Lab Data
View Screen	EUG1	YKR023W	1	Unpublished Fields Lab Data
View Screen	EUG1	CIT2	1	Unpublished Fields Lab Data
View Screen	EUG1	FMP32	1	Unpublished Fields Lab Data
View Screen	EUG1	DYN1	1	Unpublished Fields Lab Data
View Screen	EUG1	PHO87	1	Unpublished Fields Lab Data
View Screen	EUG1	MST27	1	Unpublished Fields Lab Data
View Screen	EUG1	TVP38	1	Unpublished Fields Lab Data
View Screen	EUG1	AHC2	1	Unpublished Fields Lab Data
View Screen	EUG1	YGR160W	1	Unpublished Fields Lab Data
View Screen	EUG1	SRL3	1	Unpublished Fields Lab Data
View Screen	EUG1	YDL012C	1	Unpublished Fields Lab Data
View Screen	EUG1	GTR2	1	Unpublished Fields Lab Data
View Screen	EUG1	HIF1	1	Unpublished Fields Lab Data
View Screen	EUG1	TRM3	1	Unpublished Fields Lab Data
View Screen	EUG1	YGR226C	1	Unpublished Fields Lab Data
View Screen	EUG1	PSR2	1	Unpublished Fields Lab Data
View Screen	EUG1	RPP1B	1	Unpublished Fields Lab Data
View Screen	EUG1	YGR237C	1	Unpublished Fields Lab Data
View Screen	EUG1	YLR064W	1	Unpublished Fields Lab Data
View Screen	EUG1	PFK1	1	Unpublished Fields Lab Data
View Screen	EUG1	SIC1	1	Unpublished Fields Lab Data
View Screen	EUG1	HBT1	1	Unpublished Fields Lab Data
View Screen	EUG1	SCW4	1	Unpublished Fields Lab Data
View Screen	EUG1	SEC72	1	Unpublished Fields Lab Data
View Screen	EUG1	FMP16	1	Unpublished Fields Lab Data
View Screen	EUG1	SPO13	1	Unpublished Fields Lab Data
View Screen	EUG1	YMR052C-A	1	Unpublished Fields Lab Data
View Screen	EUG1	MTQ2	1	Unpublished Fields Lab Data
View Screen	EUG1	CPR2	1	Unpublished Fields Lab Data
View Screen	EUG1	ATG16	1	Unpublished Fields Lab Data
View Screen	KAP104	EUG1	1	Unpublished Fields Lab Data
View Screen	EUG1	STB3	1	Unpublished Fields Lab Data
View Screen	EUG1	PET130	1	Unpublished Fields Lab Data
View Screen	EUG1	YMR316C-A	1	Unpublished Fields Lab Data
View Screen	PRP6	EUG1	1	Unpublished Fields Lab Data
View Screen	EUG1	IRC8	1	Unpublished Fields Lab Data
View Screen	EUG1	APC1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..146]	PSI-BLAST	140.29073	Protein disulfide isomerase, PDI
2	View Details	[147..255]	PSI-BLAST	7.39794	Protein disulfide isomerase, PDI
3	View Details	[256..330]	MSA	1.156996	View MSA. Confident ab initio structure predictions are available.
4	View Details	[331..517]	PSI-BLAST	70.70927	Thioredoxin

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2