Protein Overview: YKR017C

General Information:
Name(s) found:	YKR017C [SGD]
Description(s) found: Found 22 descriptions. SHOW ALL	Putative protein of unknown function; contains a RING finger motif [SGD]
Organism:	Saccharomyces cerevisiae
Length:	551 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGTENDQF YSFDESDSSS IELYESHNTS EFTIHGLVFP KLISVTSQDS EFDINEDEDG  60
   61 VDTIYEGMLD APLTKNNKRI LCEGSVPNLS YECLTTKGIF ERMLQRVDHL QPIFAIPSAD 120
  121 ILILLQHYDW NEERLLEVWT EKMDELLVEL GLSTTANIKK DNDYNSHFRE VEFKNDFTCI 180
  181 ICCDKKDTET FALECGHEYC INCYRHYIKD KLHEGNIITC MDCSLALKNE DIDKVMGHPS 240
  241 SSKLMDSSIK SFVQKHNRNY KWCPFADCKS IVHLRDTSSL PEYTRLHYSP FVKCNSFHRF 300
  301 CFNCGFEVHS PADCKITTAW VKKARKESEI LNWVLSHTKE CPKCSVNIEK NGGCNHMVCS 360
  361 SCKYEFCWIC EGPWAPHGKN FFQCTMYKNN EDNKSKNPQD ANKTLKKYTF YYRLFNEHEV 420
  421 SAKLDWNLGQ TLGTKVHALQ ERIGISWIDG QFLSESLKVL NEGRTVLKWS FAVAYYSDAS 480
  481 HNLTKIFVDN QMLLANAVES LSELLQIKTP EVIMKRRPEF YNKAGYVENR TTALMECGRE 540
  541 LLCKGICKAA E

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		ETP1 MOH1 NHA1 YKR017C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..154]	deduced	N/A	No confident structure predictions are available.
2	View Details	[155..293]	PSI-BLAST	2.045757	V(D)J recombination activating protein 1 (RAG1), dimerization domain
3	View Details	[294..386]	deduced	N/A	No confident structure predictions are available.
4	View Details	[387..551]	MSA	3.105962	View MSA. No confident structure predictions are available.
5	View Details	[392..551]	MSA	7.15898	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

No functions predicted.

4

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.65442784325159	bayes_pls_golite062009
small conjugating protein ligase activity	5.55686022186257	bayes_pls_golite062009
acid-amino acid ligase activity	4.59153177011595	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	3.07217714843839	bayes_pls_golite062009
binding	2.19426901055464	bayes_pls_golite062009
protein binding	1.62051249360163	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
ligase activity	0.63517530468004	bayes_pls_golite062009
transcription regulator activity	0.553991532499653	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
DNA binding	0.227671243150662	bayes_pls_golite062009
hydrolase activity	0.156835837705934	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
peptidase activity	0.121357659741468	bayes_pls_golite062009

5

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle