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Protein Overview: SPO13

General Information:
Name(s) found: SPO13 / YHR014W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Meiosis-specific protein, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachment of kinetochores to the spindle during meiosis I and meiosis II [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    condensed nuclear chromosome, centromeric region [IDALink to PubMed article]
    Biological Process: meiotic sister chromatid cohesion [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    positive regulation of sister chromatid cohesion [IGILink to PubMed article][IPILink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRKRFRLL ELGSPTHSKR KVQKPLQEKT PNLRVSPLAF KIGKEIKNKE IRKTKKTESE  60
   61 NIFNSKHVDL RLESPHPGLN FVSDAQQYSK AGDVRYLKNK SSNTLKNERQ TIERPSFDNS 120
  121 LRFEDIEQPP KSTSTPVLSQ SSQINVEREA PMFPVPYYIA PSPMYNFSPY QNFVGNPTFL 180
  181 TPSHNPNLNY AIPIQRPELL YPNVNVYDSP LFKKTRLPHQ TKSLDKEKNY QYLPIYPVSI 240
  241 SNNGDFVGQE TPRAAPKLSK KRLSNTLDVN CSDYESSGQN ATYNDSESSL N

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) IDH2 SPO13 TIF1, TIF2
    View Details Qiu et al. (2008) DAD3 DAD4 HOP1 HSK3 SPO13

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..291] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle