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Protein Overview: FRT2

General Information:
Name(s) found: FRT2 / YAL028W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: response to stress [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNAQIKSSS KGSGIDGTDR NSKDGVEKRP LEDVKQMIDA GTPDVGHKST VETKPNVGWQ  60
   61 ASHSNLAALH EKEQKYEMEH HHARHKLHRQ VIPDYTSAST AMFSDCMFNA APDKVRSLST 120
  121 MKSSGLSPKH PFNVVATFKG PFPQHSVESK PLDGGYSAKD HFPSFKMLQA QQHPAHRHYK 180
  181 DNDKYGLKSP SRSFVKDKKR LVHRFLKSME PSSSGQSKDS SALAPAFDPI LPNVISKPSK 240
  241 RPTHHSHSSD GSSSTQTDIS LQSLLYHDLE SSPKKHVSPS RPPSVASESS PAVANPIGLS 300
  301 PKDACNASFS QSSSSSLSSS SSSSSSTSFS QSVAVDPLEP PGNITYSSSN LSLNSDELDY 360
  361 YQRHIGLQLQ QTEALLKHSL KDEVLKDEND LVKNIANFDK IVKELRDLRS RTIGWKELVE 420
  421 EDYLMNLKQD FDKENPESFE ARLSDTINTN VAKLQDLEKR MASCKDRLAS RKEVMRKMES 480
  481 LLSLENSLMI SKKNVTFASK YRNEALDIVF LIIIIVICYT FKHLVSHK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AHA1 BUD3 CNS1 CPR6 DIG2 DNM1 DSF1, YNR073C FRT2 GPA2 HOM6 HSC82 HSP104 HSP82 MBB1 MRPL50 PAM1 PPT1 QNS1 RMD8 RTS1 SMT3 STI1 STP4 TDH1 UTP20 YBL104C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FRT2 FOB1 2 Unpublished Fields Lab Data
    View Screen FRT2 AKR1 2 Unpublished Fields Lab Data
    View Screen SEC17 FRT2 2 Unpublished Fields Lab Data
    View Screen GPI14 FRT2 2 Hazbun TR, et al. (2003)
    View Screen EST1 FRT2 2 Uetz P, et al. (2000)
    View Screen YIF1 FRT2 2 Unpublished Fields Lab Data
    View Screen FRT2 YIR014W 2 Unpublished Fields Lab Data
    View Screen SMC5 FRT2 2 Hazbun TR, et al. (2003)
    View Screen FRT2 NBP1 2 Unpublished Fields Lab Data
    View Screen FRT2 STB2 2 Unpublished Fields Lab Data
    View Screen FRT2 FRT1 2 Unpublished Fields Lab Data
    View Screen FRT2 ENA1 2 Unpublished Fields Lab Data
    View Screen FRT2 MNN9 2 Unpublished Fields Lab Data
    View Screen FRT2 RPL7B 1 Unpublished Fields Lab Data
    View Screen ERV46 FRT2 1 Unpublished Fields Lab Data
    View Screen FRT2 PEX29 1 Unpublished Fields Lab Data
    View Screen FRT2 PUF6 1 Unpublished Fields Lab Data
    View Screen SLY1 FRT2 1 Unpublished Fields Lab Data
    View Screen FRT2 PET122 1 Unpublished Fields Lab Data
    View Screen FRT2 RPL26B 1 Unpublished Fields Lab Data
    View Screen FRT2 CHS7 1 Unpublished Fields Lab Data
    View Screen CWC25 FRT2 1 Hazbun TR, et al. (2003)
    View Screen FRT2 FRT2 1 Unpublished Fields Lab Data
    View Screen FRT2 EPS1 1 Unpublished Fields Lab Data
    View Screen FRT2 PDR3 1 Unpublished Fields Lab Data
    View Screen FRT2 HSP26 1 Unpublished Fields Lab Data
    View Screen TPT1 FRT2 1 Unpublished Fields Lab Data
    View Screen FRT2 UMP1 1 Unpublished Fields Lab Data
    View Screen FRT2 YCL065W 1 Unpublished Fields Lab Data
    View Screen FRT2 YNL146W 1 Unpublished Fields Lab Data
    View Screen FRT2 SED4 1 Unpublished Fields Lab Data
    View Screen FRT2 PCL1 1 Unpublished Fields Lab Data
    View Screen FRT2 GRX6 1 Unpublished Fields Lab Data
    View Screen FRT2 ADY3 1 Unpublished Fields Lab Data
    View Screen FRT2 SCD5 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..528] deduced N/A No confident structure predictions are available.
    2 View Details [243..340] deduced N/A No confident structure predictions are available.
    3 View Details [341..528] FFAS03 1.09 No description for 2fxmA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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