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Protein Overview: UMP1

General Information:
Name(s) found: UMP1 / YBR173C [SGD]
Description(s) found:
Found 35 descriptions.
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  • Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to DNA damage stimulus [IDALink to PubMed article][IEPLink to PubMed article]
    proteasome assembly [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIVPQDTFK SQVSTDQDKS VLSSAVPSLP DTLRQQEGGA VPLSTQLNDR HPLESTLKNW  60
   61 ETTQRQRQME QYRQIFGIAE PMKRTMEMEI VNRTDFNPLS TNGSIHRDIL LNKECSIDWE 120
  121 DVYPGTGLQA STMVGDDVHS KIEKQLGI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP1 PUP2 PUP3 SCL1 UMP1
    View Details Krogan NJ, et al. (2006) ACK1 CIN8 DCG1 GNA1 MCM6 MLP1 PMD1 PMT4 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP1 PUP2 PUP3 RFT1 SCL1 SGA1 SNQ2 TOS8 UMP1 YCR076C YDR179W-A YJL132W YKR070W YLR211C YLR290C
    View Details Qiu et al. (2008) BLM10 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP1 PUP2 PUP3 SCL1 UMP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SCL1 UMP1 2 Unpublished Fields Lab Data
    View Screen PRP16 UMP1 2 Unpublished Fields Lab Data
    View Screen PRE2 UMP1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UMP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] Pfam 66.522879 No description for PF05348.2 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle