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Protein Overview: TOR_ARATH

General Information:
Name(s) found: TOR_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|22330143|ref|NP_175425.2| TOR (TARGET OF RAPAMYCIN); 1-phosphatidylinositol-3-kinase/ protein binding [Arabidopsis thaliana] [NCBI NR]
  • gi|12002902|gb|AAG43423.1|AF178967_1 pTOR [Arabidopsis thaliana] [NCBI NR]
  • Serine/threonine-protein kinase TOR OS=Arabidopsis thaliana GN=TOR PE=1 SV=1 [Swiss-Prot]
  • pTOR [Arabidopsis thaliana]gi|22330143|ref|NP_175425.2| target of rapamycin protein (TOR) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Target of rapamycin protein (TOR) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: TOR | TOR (TARGET OF RAPAMYCIN) | chr1:18526294-18543287 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • TOR (TARGET OF RAPAMYCIN) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • pTOR [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: TOR | target of rapamycin | chr1:18522626-18539619 REVERSE LENGTH=2481 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 2481 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IEA]
    Biological Process: embryonic development ending in seed dormancy [IMP]
    Molecular Function: protein binding [IPI]
    1-phosphatidylinositol-3-kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSSQSFVA GRPASMASPS QSHRFCGPSA TASGGGSFDT LNRVIADLCS RGNPKEGAPL  60
   61 AFRKHVEEAV RDLSGEASSR FMEQLYDRIA NLIESTDVAE NMGALRAIDE LTEIGFGENA 120
  121 TKVSRFAGYM RTVFELKRDP EILVLASRVL GHLARAGGAM TSDEVEFQMK TAFDWLRVDR 180
  181 VEYRRFAAVL ILKEMAENAS TVFNVHVPEF VDAIWVALRD PQLQVRERAV EALRACLRVI 240
  241 EKRETRWRVQ WYYRMFEATQ DGLGRNAPVH SIHGSLLAVG ELLRNTGEFM MSRYREVAEI 300
  301 VLRYLEHRDR LVRLSITSLL PRIAHFLRDR FVTNYLTICM NHILTVLRIP AERASGFIAL 360
  361 GEMAGALDGE LIHYLPTIMS HLRDAIAPRK GRPLLEAVAC VGNIAKAMGS TVETHVRDLL 420
  421 DVMFSSSLSS TLVDALDQIT ISIPSLLPTV QDRLLDCISL VLSKSHYSQA KPPVTIVRGS 480
  481 TVGMAPQSSD PSCSAQVQLA LQTLARFNFK GHDLLEFARE SVVVYLDDED AATRKDAALC 540
  541 CCRLIANSLS GITQFGSSRS TRAGGRRRRL VEEIVEKLLR TAVADADVTV RKSIFVALFG 600
  601 NQCFDDYLAQ ADSLTAIFAS LNDEDLDVRE YAISVAGRLS EKNPAYVLPA LRRHLIQLLT 660
  661 YLELSADNKC REESAKLLGC LVRNCERLIL PYVAPVQKAL VARLSEGTGV NANNNIVTGV 720
  721 LVTVGDLARV GGLAMRQYIP ELMPLIVEAL MDGAAVAKRE VAVSTLGQVV QSTGYVVTPY 780
  781 KEYPLLLGLL LKLLKGDLVW STRREVLKVL GIMGALDPHV HKRNQQSLSG SHGEVPRGTG 840
  841 DSGQPIPSID ELPVELRPSF ATSEDYYSTV AINSLMRILR DASLLSYHKR VVRSLMIIFK 900
  901 SMGLGCVPYL PKVLPELFHT VRTSDENLKD FITWGLGTLV SIVRQHIRKY LPELLSLVSE 960
  961 LWSSFTLPGP IRPSRGLPVL HLLEHLCLAL NDEFRTYLPV ILPCFIQVLG DAERFNDYTY1020
 1021 VPDILHTLEV FGGTLDEHMH LLLPALIRLF KVDAPVAIRR DAIKTLTRVI PCVQVTGHIS1080
 1081 ALVHHLKLVL DGKNDELRKD AVDALCCLAH ALGEDFTIFI ESIHKLLLKH RLRHKEFEEI1140
 1141 HARWRRREPL IVATTATQQL SRRLPVEVIR DPVIENEIDP FEEGTDRNHQ VNDGRLRTAG1200
 1201 EASQRSTKED WEEWMRHFSI ELLKESPSPA LRTCAKLAQL QPFVGRELFA AGFVSCWAQL1260
 1261 NESSQKQLVR SLEMAFSSPN IPPEILATLL NLAEFMEHDE KPLPIDIRLL GALAEKCRVF1320
 1321 AKALHYKEME FEGPRSKRMD ANPVAVVEAL IHINNQLHQH EAAVGILTYA QQHLDVQLKE1380
 1381 SWYEKLQRWD DALKAYTLKA SQTTNPHLVL EATLGQMRCL AALARWEELN NLCKEYWSPA1440
 1441 EPSARLEMAP MAAQAAWNMG EWDQMAEYVS RLDDGDETKL RGLASPVSSG DGSSNGTFFR1500
 1501 AVLLVRRAKY DEAREYVERA RKCLATELAA LVLESYERAY SNMVRVQQLS ELEEVIEYYT1560
 1561 LPVGNTIAEE RRALIRNMWT QRIQGSKRNV EVWQALLAVR ALVLPPTEDV ETWLKFASLC1620
 1621 RKSGRISQAK STLLKLLPFD PEVSPENMQY HGPPQVMLGY LKYQWSLGEE RKRKEAFTKL1680
 1681 QILTRELSSV PHSQSDILAS MVSSKGANVP LLARVNLKLG TWQWALSSGL NDGSIQEIRD1740
 1741 AFDKSTCYAP KWAKAWHTWA LFNTAVMSHY ISRGQIASQY VVSAVTGYFY SIACAANAKG1800
 1801 VDDSLQDILR LLTLWFNHGA TADVQTALKT GFSHVNINTW LVVLPQIIAR IHSNNRAVRE1860
 1861 LIQSLLIRIG ENHPQALMYP LLVACKSISN LRRAAAQEVV DKVRQHSGAL VDQAQLVSHE1920
 1921 LIRVAILWHE MWHEALEEAS RLYFGEHNIE GMLKVLEPLH DMLDEGVKKD STTIQERAFI1980
 1981 EAYRHELKEA HECCCNYKIT GKDAELTQAW DLYYHVFKRI DKQLASLTTL DLESVSPELL2040
 2041 LCRDLELAVP GTYRADAPVV TISSFSRQLV VITSKQRPRK LTIHGNDGED YAFLLKGHED2100
 2101 LRQDERVMQL FGLVNTLLEN SRKTAEKDLS IQRYSVIPLS PNSGLIGWVP NCDTLHHLIR2160
 2161 EHRDARKIIL NQENKHMLSF APDYDNLPLI AKVEVFEYAL ENTEGNDLSR VLWLKSRSSE2220
 2221 VWLERRTNYT RSLAVMSMVG YILGLGDRHP SNLMLHRYSG KILHIDFGDC FEASMNREKF2280
 2281 PEKVPFRLTR MLVKAMEVSG IEGNFRSTCE NVMQVLRTNK DSVMAMMEAF VHDPLINWRL2340
 2341 FNFNEVPQLA LLGNNNPNAP ADVEPDEEDE DPADIDLPQP QRSTREKEIL QAVNMLGDAN2400
 2401 EVLNERAVVV MARMSHKLTG RDFSSSAIPS NPIADHNNLL GGDSHEVEHG LSVKVQVQKL2460
 2461 INQATSHENL CQNYVGWCPF W

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] PSI-BLAST 35.045757 Importin beta
    2 View Details [308..1148] PSI-BLAST 67.69897 No description for 2h4mA was found.
    3 View Details [1149..1226] PSI-BLAST 72.221849 No description for 2iaeA was found.
    4 View Details [1227..1623] FFAS03 2.05 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    5 View Details [1624..1799] PSI-BLAST 7.69897 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
    6 View Details [1800..2393] PSI-BLAST 94.69897 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain
    7 View Details [2394..2481] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.64850159998065 bayes_pls_golite062009
  • protein binding
    		•  2.56368359497233 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36976362065221 bayes_pls_golite062009
  • DNA binding
    		•  1.72247907299633 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.63537681687141 bayes_pls_golite062009
  • transferase activity
    		•  1.17886241606889 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13603983412087 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13603983412087 bayes_pls_golite062009
  • transcription factor activity
    		•  1.0205750374806 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.831782705534701 bayes_pls_golite062009
  • hydrolase activity
    		•  0.823693097127061 bayes_pls_golite062009
  • transcription factor binding
    		•  0.447234745044969 bayes_pls_golite062009
  • receptor activity
    		•  0.383201466191514 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.201108481303385 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.177518071994821 bayes_pls_golite062009
  • signal sequence binding
    		•  0.144756387712192 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0514451541233234 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0290076512914955 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0194562796536073 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • protein transporter activity
    		•  3.92743254165888 bayes_pls_golite062009
  • clathrin binding
    		•  3.06608550312523 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • GTPase activity
    		•  2.07905155389729 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.81975432004022 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.7769021678395 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.77299972560401 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.6878868450299 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • receptor activity
    		•  1.57112777506542 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.56748951434625 bayes_pls_golite062009
  • phosphoinositide 3-kinase activity
    		•  1.5013287968167 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.4571078357189 bayes_pls_golite062009
  • 1-phosphatidylinositol-3-kinase activity
    		•  1.43713739644553 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • DNA binding
    		•  1.10840413397037 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04820278247375 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.959360414036299 bayes_pls_golite062009
  • transcription factor activity
    		•  0.904613968623246 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.77052454980864 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.655603104242089 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.568332175782799 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • PTB domain binding
    		•  0.43689836431804 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.41587987561486 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.41507385950821 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.284465446035567 bayes_pls_golite062009
  • kinase binding
    		•  0.26752427107238 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.267404531445803 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  0.26602283402868 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  0.26602283402868 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • actin binding
    		•  0.144822861207099 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  0.0935103343162811 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.08504542461349 bayes_pls_golite062009
  • hydrolase activity
    		•  0.056449407710228 bayes_pls_golite062009
  • growth factor binding
    		•  0.0526340287295695 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • 3-phosphoinositide-dependent protein kinase binding
    		•  0.00690652278439874 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00674998152095019 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle