| Protein: | TOR_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 2481 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOR_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
1838.0 | [0..1] | [2479..1] |
|
Region A: Residues: [1-307] |
1 11 21 31 41 51
| | | | | |
1 MSTSSQSFVA GRPASMASPS QSHRFCGPSA TASGGGSFDT LNRVIADLCS RGNPKEGAPL 60
61 AFRKHVEEAV RDLSGEASSR FMEQLYDRIA NLIESTDVAE NMGALRAIDE LTEIGFGENA 120
121 TKVSRFAGYM RTVFELKRDP EILVLASRVL GHLARAGGAM TSDEVEFQMK TAFDWLRVDR 180
181 VEYRRFAAVL ILKEMAENAS TVFNVHVPEF VDAIWVALRD PQLQVRERAV EALRACLRVI 240
241 EKRETRWRVQ WYYRMFEATQ DGLGRNAPVH SIHGSLLAVG ELLRNTGEFM MSRYREVAEI 300
301 VLRYLEH
|
| Detection Method: |  |
| Confidence: | 35.045757 |
| Match: | 1qgkA |
| Description: | Importin beta |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [308-1148] |
1 11 21 31 41 51
| | | | | |
1 RDRLVRLSIT SLLPRIAHFL RDRFVTNYLT ICMNHILTVL RIPAERASGF IALGEMAGAL 60
61 DGELIHYLPT IMSHLRDAIA PRKGRPLLEA VACVGNIAKA MGSTVETHVR DLLDVMFSSS 120
121 LSSTLVDALD QITISIPSLL PTVQDRLLDC ISLVLSKSHY SQAKPPVTIV RGSTVGMAPQ 180
181 SSDPSCSAQV QLALQTLARF NFKGHDLLEF ARESVVVYLD DEDAATRKDA ALCCCRLIAN 240
241 SLSGITQFGS SRSTRAGGRR RRLVEEIVEK LLRTAVADAD VTVRKSIFVA LFGNQCFDDY 300
301 LAQADSLTAI FASLNDEDLD VREYAISVAG RLSEKNPAYV LPALRRHLIQ LLTYLELSAD 360
361 NKCREESAKL LGCLVRNCER LILPYVAPVQ KALVARLSEG TGVNANNNIV TGVLVTVGDL 420
421 ARVGGLAMRQ YIPELMPLIV EALMDGAAVA KREVAVSTLG QVVQSTGYVV TPYKEYPLLL 480
481 GLLLKLLKGD LVWSTRREVL KVLGIMGALD PHVHKRNQQS LSGSHGEVPR GTGDSGQPIP 540
541 SIDELPVELR PSFATSEDYY STVAINSLMR ILRDASLLSY HKRVVRSLMI IFKSMGLGCV 600
601 PYLPKVLPEL FHTVRTSDEN LKDFITWGLG TLVSIVRQHI RKYLPELLSL VSELWSSFTL 660
661 PGPIRPSRGL PVLHLLEHLC LALNDEFRTY LPVILPCFIQ VLGDAERFND YTYVPDILHT 720
721 LEVFGGTLDE HMHLLLPALI RLFKVDAPVA IRRDAIKTLT RVIPCVQVTG HISALVHHLK 780
781 LVLDGKNDEL RKDAVDALCC LAHALGEDFT IFIESIHKLL LKHRLRHKEF EEIHARWRRR 840
841 E
|
| Detection Method: | |
| Confidence: | 67.69897 |
| Match: | 2h4mA |
| Description: | No description for 2h4mA was found. |
|
Region A: Residues: [1149-1226] |
1 11 21 31 41 51
| | | | | |
1 PLIVATTATQ QLSRRLPVEV IRDPVIENEI DPFEEGTDRN HQVNDGRLRT AGEASQRSTK 60
61 EDWEEWMRHF SIELLKES
|
| Detection Method: | |
| Confidence: | 72.221849 |
| Match: | 2iaeA |
| Description: | No description for 2iaeA was found. |
|
Region A: Residues: [1227-1623] |
1 11 21 31 41 51
| | | | | |
1 PSPALRTCAK LAQLQPFVGR ELFAAGFVSC WAQLNESSQK QLVRSLEMAF SSPNIPPEIL 60
61 ATLLNLAEFM EHDEKPLPID IRLLGALAEK CRVFAKALHY KEMEFEGPRS KRMDANPVAV 120
121 VEALIHINNQ LHQHEAAVGI LTYAQQHLDV QLKESWYEKL QRWDDALKAY TLKASQTTNP 180
181 HLVLEATLGQ MRCLAALARW EELNNLCKEY WSPAEPSARL EMAPMAAQAA WNMGEWDQMA 240
241 EYVSRLDDGD ETKLRGLASP VSSGDGSSNG TFFRAVLLVR RAKYDEAREY VERARKCLAT 300
301 ELAALVLESY ERAYSNMVRV QQLSELEEVI EYYTLPVGNT IAEERRALIR NMWTQRIQGS 360
361 KRNVEVWQAL LAVRALVLPP TEDVETWLKF ASLCRKS
|
| Detection Method: | |
| Confidence: | 2.05 |
| Match: | 1w3bA |
| Description: | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.64850159998065 | bayes_pls_golite062009 |
| protein binding | 2.56368359497233 | bayes_pls_golite062009 |
| transcription regulator activity | 2.36976362065221 | bayes_pls_golite062009 |
| DNA binding | 1.72247907299633 | bayes_pls_golite062009 |
| nucleic acid binding | 1.63537681687141 | bayes_pls_golite062009 |
| transferase activity | 1.17886241606889 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13603983412087 | bayes_pls_golite062009 |
| signal transducer activity | 1.13603983412087 | bayes_pls_golite062009 |
| transcription factor activity | 1.0205750374806 | bayes_pls_golite062009 |
| transcription repressor activity | 0.831782705534701 | bayes_pls_golite062009 |
| hydrolase activity | 0.823693097127061 | bayes_pls_golite062009 |
| transcription factor binding | 0.447234745044969 | bayes_pls_golite062009 |
| receptor activity | 0.383201466191514 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.201108481303385 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.177518071994821 | bayes_pls_golite062009 |
| signal sequence binding | 0.144756387712192 | bayes_pls_golite062009 |
| transcription activator activity | 0.0514451541233234 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.0290076512914955 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.0194562796536073 | bayes_pls_golite062009 |
|
Region A: Residues: [1624-1799] |
1 11 21 31 41 51
| | | | | |
1 GRISQAKSTL LKLLPFDPEV SPENMQYHGP PQVMLGYLKY QWSLGEERKR KEAFTKLQIL 60
61 TRELSSVPHS QSDILASMVS SKGANVPLLA RVNLKLGTWQ WALSSGLNDG SIQEIRDAFD 120
121 KSTCYAPKWA KAWHTWALFN TAVMSHYISR GQIASQYVVS AVTGYFYSIA CAANAK
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 2fo7A |
| Description: | Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1800-2393] |
1 11 21 31 41 51
| | | | | |
1 GVDDSLQDIL RLLTLWFNHG ATADVQTALK TGFSHVNINT WLVVLPQIIA RIHSNNRAVR 60
61 ELIQSLLIRI GENHPQALMY PLLVACKSIS NLRRAAAQEV VDKVRQHSGA LVDQAQLVSH 120
121 ELIRVAILWH EMWHEALEEA SRLYFGEHNI EGMLKVLEPL HDMLDEGVKK DSTTIQERAF 180
181 IEAYRHELKE AHECCCNYKI TGKDAELTQA WDLYYHVFKR IDKQLASLTT LDLESVSPEL 240
241 LLCRDLELAV PGTYRADAPV VTISSFSRQL VVITSKQRPR KLTIHGNDGE DYAFLLKGHE 300
301 DLRQDERVMQ LFGLVNTLLE NSRKTAEKDL SIQRYSVIPL SPNSGLIGWV PNCDTLHHLI 360
361 REHRDARKII LNQENKHMLS FAPDYDNLPL IAKVEVFEYA LENTEGNDLS RVLWLKSRSS 420
421 EVWLERRTNY TRSLAVMSMV GYILGLGDRH PSNLMLHRYS GKILHIDFGD CFEASMNREK 480
481 FPEKVPFRLT RMLVKAMEVS GIEGNFRSTC ENVMQVLRTN KDSVMAMMEA FVHDPLINWR 540
541 LFNFNEVPQL ALLGNNNPNA PADVEPDEED EDPADIDLPQ PQRSTREKEI LQAV
|
| Detection Method: | |
| Confidence: | 94.69897 |
| Match: | 1e7uA |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein transporter activity | 3.92743254165888 | bayes_pls_golite062009 |
| clathrin binding | 3.06608550312523 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| GTPase activity | 2.07905155389729 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 1.81975432004022 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.7769021678395 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 1.77299972560401 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.6878868450299 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| receptor activity | 1.57112777506542 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 1.5013287968167 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.4571078357189 | bayes_pls_golite062009 |
| 1-phosphatidylinositol-3-kinase activity | 1.43713739644553 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| DNA binding | 1.10840413397037 | bayes_pls_golite062009 |
| nucleic acid binding | 1.04820278247375 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| transcription factor activity | 0.904613968623246 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 0.77052454980864 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| insulin receptor activity | 0.655603104242089 | bayes_pls_golite062009 |
| transcription repressor activity | 0.568332175782799 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| PTB domain binding | 0.43689836431804 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.41507385950821 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.284465446035567 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.267404531445803 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.26602283402868 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.26602283402868 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252495966234234 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.226380819487924 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.217517113570989 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.178770060806735 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 0.175241020572885 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 0.174922130116569 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| actin binding | 0.144822861207099 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 0.0935103343162811 | bayes_pls_golite062009 |
| MAP kinase activity | 0.08504542461349 | bayes_pls_golite062009 |
| hydrolase activity | 0.056449407710228 | bayes_pls_golite062009 |
| growth factor binding | 0.0526340287295695 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.00690652278439874 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [2394-2481] |
1 11 21 31 41 51
| | | | | |
1 NMLGDANEVL NERAVVVMAR MSHKLTGRDF SSSAIPSNPI ADHNNLLGGD SHEVEHGLSV 60
61 KVQVQKLINQ ATSHENLCQN YVGWCPFW
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
