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View Structure Prediction Details

Protein: CE11190
Organism: Caenorhabditis elegans
Length: 746 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE11190.

Description E-value Query
Range		 Subject
Range
gi|74006746 - gi|74006746|ref|XP_861599.1| PREDICTED: similar to DEAD-box protein 3, X-chromosomal (Helicase-like ...
 389.0 [0..33] [605..52]

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Predicted Domain #1
Region A:
Residues: [1-103] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNISIPGNW QTCDVEAMDG DFDDNMLQFL GSFEEVLPEG VEVETKKGMK KKNKPKKVEN  60
   61 TERPEEDAKC VEERRLAKKL RRKEQMAANR KQKKERLAKR KQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-159] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAESSAKKSE NATETTTEKP KEQKKRKGGE NGDTGKPKKS KKEASKKTDI SAWKQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.69897
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #3
Region A:
Residues: [160-746] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFLPNEVLEA IEQMGFSEPT EIQSAVLPAA VRDRQDVLGA AETGSGKTLA FGIPLVARLL  60
   61 ESSDDSQETE STEVRGPRAL IVAPTRELVI QIMKHINALI STTQLIATSI VGGLAQVKQE 120
  121 RIISQQRPDI VVATPGRLWA MMQEAETGEF LAEWKDLKCL VVDETDRMVE EGYFAELTHI 180
  181 LNKIHEESEK EKLQTLVFSA TLTFAKAQDV AEEEKKKAKE LSSQQKIQRL IKLTGLRENK 240
  241 HKVIDLTRQM GTAGCLVEAR INCGNLLEKD TSLVYLLTRY PGRTIVFVNS IDAARRLYSV 300
  301 LKSVNIDPMI LHAKMIQKQR LKNLEKFSES KNAVLLATDV AARGLDIQGI DHVIHYQVPK 360
  361 KVEIYIHRSG RTARASHRGL TVVLVDPPSR QFYMKLCKGL NRMQDLNVFP IDFEPLMNAI 420
  421 KKRVRLASEI DSLGFRCKKI KMSESWFEKA ARAADLDYDE TRHREMDGLN LEVDTMVQKS 480
  481 RQLQAQLRTE LSLPLPRVDG SDSMKTKYIT PEIVARLRSV GDNAIDVLNQ KIDETKEWKR 540
  541 KSRKATREDE MNSMKKSLKS SQKNKERLAE KKKKEKAAKV TKLSETD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1oywA
Description: Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 9.07129841752891 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 8.58358908736821 bayes_pls_golite062009
translation initiation factor activity 7.79457008386475 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 7.35625288284796 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.62734320850541 bayes_pls_golite062009
translation factor activity, nucleic acid binding 4.98637553020315 bayes_pls_golite062009
translation regulator activity 4.94658029227343 bayes_pls_golite062009
4.704140727858 bayes_pls_golite062009
structural constituent of ribosome 4.56509805974548 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 4.03326929098701 bayes_pls_golite062009
hydrolase activity 3.63069754092699 bayes_pls_golite062009
structural molecule activity 3.58406348799895 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.4837867129694 bayes_pls_golite062009
ion transmembrane transporter activity 3.35436118751376 bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism 3.28373827150339 bayes_pls_golite062009
DNA clamp loader activity 3.22518920754305 bayes_pls_golite062009
protein-DNA loading ATPase activity 3.19273435123154 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
cation transmembrane transporter activity 3.08390071341252 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
motor activity 2.79327761685782 bayes_pls_golite062009
microtubule motor activity 2.74365461017633 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
translation release factor activity 2.49148102494524 bayes_pls_golite062009
translation termination factor activity 2.46464632547226 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
cation-transporting ATPase activity 2.31476707827367 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.18118655708491 bayes_pls_golite062009
RNA cap binding 2.17871969124431 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
cytoskeletal protein binding 1.40488517180956 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
voltage-gated cation channel activity 1.3493704216639 bayes_pls_golite062009
DNA strand annealing activity 1.30936388901516 bayes_pls_golite062009
telomeric DNA binding 1.28350783207533 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
protein transporter activity 1.25342367751911 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
voltage-gated ion channel activity 1.23468617030519 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
voltage-gated channel activity 1.216998547662 bayes_pls_golite062009
potassium channel activity 1.20877745413881 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
tubulin binding 0.979946830272106 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
cation channel activity 0.940476916156422 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
microtubule binding 0.907162506177187 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
actin binding 0.883285269827407 bayes_pls_golite062009
transcription repressor activity 0.862685397469217 bayes_pls_golite062009
ion channel activity 0.848261056209476 bayes_pls_golite062009
channel activity 0.806331380134838 bayes_pls_golite062009
passive transmembrane transporter activity 0.806331380134838 bayes_pls_golite062009
substrate-specific channel activity 0.799997700906738 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
transcription elongation regulator activity 0.752795599437554 bayes_pls_golite062009
ribonuclease activity 0.712344060953362 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.69784475011795 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
peptidase activity 0.654073677905812 bayes_pls_golite062009
gated channel activity 0.650050847753837 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 0.563503770238611 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
anion transmembrane transporter activity 0.43332053110728 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.347363231484033 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.328170855722634 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
guanyl nucleotide binding 0.296406132096546 bayes_pls_golite062009
GTP binding 0.295705904888768 bayes_pls_golite062009
guanyl ribonucleotide binding 0.29028316917561 bayes_pls_golite062009
signal transducer activity 0.286367085584159 bayes_pls_golite062009
molecular transducer activity 0.286367085584159 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.243902356228423 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.226231702119567 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
protein transmembrane transporter activity 0.0378638259240902 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0360186926687502 bayes_pls_golite062009
signal sequence binding 6.53725193420218E-4 bayes_pls_golite062009
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