| Protein: | Pkc53E-PB |
| Organism: | Drosophila melanogaster |
| Length: | 679 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pkc53E-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
550.0 | [0..1] | [679..1] |
|
Region A: Residues: [1-105] |
1 11 21 31 41 51
| | | | | |
1 MSEGSDNNGD PQQQGAEGEA VGENKMKSRL RKGALKKKNV FNVKDHCFIA RFFKQPTFCS 60
61 HCKDFICGYQ SGYAWMGFGK QGFQCQVCSY VVHKRCHEYV TFICP
|
| Detection Method: |  |
| Confidence: | 4.39794 |
| Match: | 1ptqA |
| Description: | PROTEIN KINASE C DELTA CYS2 DOMAIN |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 2.86705824967236 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| protein binding | 2.34145982999922 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.10625597744594 | bayes_pls_golite062009 |
| DNA binding | 2.06132216820898 | bayes_pls_golite062009 |
| kinase activity | 2.03632850156074 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91441035614579 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.8531437045627 | bayes_pls_golite062009 |
| protein kinase activity | 1.62921423829738 | bayes_pls_golite062009 |
| transferase activity | 1.4550521488922 | bayes_pls_golite062009 |
| transcription factor activity | 1.39657429296564 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.39167263636091 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.37139209958305 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.10685156896266 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.911061212692491 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.907368864863833 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.85935039193003 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.661240850692236 | bayes_pls_golite062009 |
| kinase binding | 0.494958567742569 | bayes_pls_golite062009 |
| cation binding | 0.416345209135028 | bayes_pls_golite062009 |
| metal ion binding | 0.416345209135028 | bayes_pls_golite062009 |
| ion binding | 0.411417584934096 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
|
Region A: Residues: [106-196] |
1 11 21 31 41 51
| | | | | |
1 GKDKGIDSDS PKTQHNFEPF TYAGPTFCDH CGSLLYGIYH QGLKCSACDM NVHARCKENV 60
61 PSLCGCDHTE RRGRIYLEIN VKENLLTVQI K
|
| Detection Method: | |
| Confidence: | 6.30103 |
| Match: | 1tbnA |
| Description: | NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 2.86705824967236 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| protein binding | 2.34145982999922 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.10625597744594 | bayes_pls_golite062009 |
| DNA binding | 2.06132216820898 | bayes_pls_golite062009 |
| kinase activity | 2.03632850156074 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91441035614579 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.8531437045627 | bayes_pls_golite062009 |
| protein kinase activity | 1.62921423829738 | bayes_pls_golite062009 |
| transferase activity | 1.4550521488922 | bayes_pls_golite062009 |
| transcription factor activity | 1.39657429296564 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.39167263636091 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.37139209958305 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.10685156896266 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.956859696337723 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.911061212692491 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.907368864863833 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.85935039193003 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.661240850692236 | bayes_pls_golite062009 |
| kinase binding | 0.494958567742569 | bayes_pls_golite062009 |
| cation binding | 0.416345209135028 | bayes_pls_golite062009 |
| metal ion binding | 0.416345209135028 | bayes_pls_golite062009 |
| ion binding | 0.411417584934096 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
|
Region A: Residues: [197-596] |
1 11 21 31 41 51
| | | | | |
1 EGRNLIPMDP NGLSDPYVKV KLIPDDKDQS KKKTRTIKAC LNPVWNETLT YDLKPEDKDR 60
61 RILIEVWDWD RTSRNDFMGA LSFGISEIIK NPTNGWFKLL TQDEGEYYNV PCADDEQDLL 120
121 KLKQKPSQKK PMVMRSDTNT HTSSKKDMIR ATDFNFIKVL GKGSFGKVLL AERKGSEELY 180
181 AIKILKKDVI IQDDDVECTM IEKRVLALGE KPPFLVQLHS CFQTMDRLFF VMEYVNGGDL 240
241 MFQIQQFGKF KEPVAVFYAA EIAAGLFFLH TKGILYRDLK LDNVLLDADG HVKIADFGMC 300
301 KENIVGDKTT KTFCGTPDYI APEIILYQPY GKSVDWWAYG VLLYEMLVGQ PPFDGEDEEE 360
361 LFAAITDHNV SYPKSLSKEA KEACKGFLTK QPNKRLGCGS
|
| Detection Method: | |
| Confidence: | 44.0 |
| Match: | 1opkA |
| Description: | Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| SH2 domain binding | 3.03401803018883 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| insulin binding | 2.0719180171079 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| PTB domain binding | 1.96099803532698 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 1.5013287968167 | bayes_pls_golite062009 |
| 1-phosphatidylinositol-3-kinase activity | 1.43713739644553 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| GTPase activity | 1.28660784978431 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 1.24312972088703 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| structural constituent of muscle | 1.19908793854422 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| structural molecule activity | 1.10436308210353 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 1.03150090191995 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| transcription repressor activity | 0.889321498544699 | bayes_pls_golite062009 |
| transcription activator activity | 0.846644791435606 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| vinculin binding | 0.666656406096231 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| insulin receptor activity | 0.585036697436369 | bayes_pls_golite062009 |
| acetylcholine receptor activator activity | 0.539048303150161 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| photoreceptor activity | 0.187612589250841 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| cation binding | 0.046173055856133 | bayes_pls_golite062009 |
| metal ion binding | 0.046173055856133 | bayes_pls_golite062009 |
| ion binding | 0.0389662058697694 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 0.0386657159233388 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [597-679] |
1 11 21 31 41 51
| | | | | |
1 SGEEDVRLHP FFRRIDWEKI ENREVQPPFK PKIKHRKDVS NFDKQFTSEK TDLTPTDKVF 60
61 MMNLDQSEFV GFSYMNPEYV FSP
|
| Detection Method: | |
| Confidence: | 91.69897 |
| Match: | 2i0eA |
| Description: | No description for 2i0eA was found. |
