Protein: | PDR12 |
Organism: | Saccharomyces cerevisiae |
Length: | 1511 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR12.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [1..1471] | [475..1942] |
|
0.0 | [10..1375] | [6..1355] |
|
0.0 | [7..1499] | [57..1545] |
|
0.0 | [2..1481] | [7..1490] |
|
0.0 | [6..1388] | [28..1408] |
|
0.0 | [6..1471] | [76..1543] |
|
0.0 | [1..1476] | [6..1498] |
|
0.0 | [1..1473] | [1..1483] |
Region A: Residues: [1-85] |
1 11 21 31 41 51 | | | | | | 1 MSSTDEHIEK DISSRSNHDD DYANSVQSYA ASEGQVDNED LAATSQLSRH LSNILSNEEG 60 61 IERLESMARV ISHKTKKEMD SFEIN |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
SCOP Match |
SCOP Description | ||
View | Download | 0.753 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
View | Download | 0.728 | a.60.9 | lambda integrase-like, N-terminal domain |
View | Download | 0.733 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
View | Download | 0.646 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
View | Download | 0.612 | a.29.4 | RecG, N-terminal domain |
View | Download | 0.609 | a.126.1 | Serum albumin-like |
View | Download | 0.600 | a.7.6 | Ribosomal protein S20 |
View | Download | 0.530 | a.118.1 | ARM repeat |
View | Download | 0.524 | a.74.1 | Cyclin-like |
View | Download | 0.523 | a.144.1 | PABC (PABP) domain |
View | Download | 0.501 | a.144.1 | PABC (PABP) domain |
View | Download | 0.491 | a.3.1 | Cytochrome c |
View | Download | 0.476 | a.46.1 | Methionine synthase domain |
View | Download | 0.473 | a.61.1 | Retroviral matrix proteins |
View | Download | 0.468 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
View | Download | 0.468 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
View | Download | 0.463 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
View | Download | 0.461 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
View | Download | 0.461 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
View | Download | 0.457 | a.156.1 | S13-like H2TH domain |
View | Download | 0.441 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
View | Download | 0.433 | a.39.1 | EF-hand |
View | Download | 0.414 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
View | Download | 0.412 | a.156.1 | S13-like H2TH domain |
View | Download | 0.412 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
View | Download | 0.406 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
View | Download | 0.370 | a.39.1 | EF-hand |
View | Download | 0.367 | a.64.1 | Saposin |
View | Download | 0.367 | a.51.1 | Cytochrome c oxidase subunit h |
View | Download | 0.366 | a.60.1 | SAM/Pointed domain |
View | Download | 0.365 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
View | Download | 0.364 | a.24.17 | Group V grass pollen allergen |
View | Download | 0.358 | a.112.1 | Description not found. |
View | Download | 0.353 | a.1.1 | Globin-like |
View | Download | 0.347 | a.24.4 | Hemerythrin |
View | Download | 0.347 | a.57.1 | Protein HNS-dependent expression A; HdeA |
View | Download | 0.338 | a.1.1 | Globin-like |
View | Download | 0.332 | a.4.1 | Homeodomain-like |
View | Download | 0.330 | a.21.1 | HMG-box |
View | Download | 0.329 | a.4.5 | "Winged helix" DNA-binding domain |
View | Download | 0.326 | a.22.1 | Histone-fold |
View | Download | 0.325 | c.84.1 | Phosphoglucomutase, first 3 domains |
View | Download | 0.323 | a.142.1 | PTS-regulatory domain, PRD |
View | Download | 0.320 | a.4.5 | "Winged helix" DNA-binding domain |
View | Download | 0.318 | a.4.5 | "Winged helix" DNA-binding domain |
View | Download | 0.318 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
View | Download | 0.312 | a.64.1 | Saposin |
View | Download | 0.305 | a.4.5 | "Winged helix" DNA-binding domain |
View | Download | 0.300 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
View | Download | 0.299 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
View | Download | 0.292 | a.2.3 | Chaperone J-domain |
View | Download | 0.292 | a.60.13 | Putative methyltransferase TM0872, insert domain |
View | Download | 0.289 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
View | Download | 0.288 | d.58.25 | Killer toxin KP6 alpha-subunit |
View | Download | 0.287 | a.4.1 | Homeodomain-like |
View | Download | 0.280 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
View | Download | 0.275 | a.118.8 | TPR-like |
View | Download | 0.275 | a.4.1 | Homeodomain-like |
View | Download | 0.264 | a.5.3 | N-terminal domain of phosphatidylinositol transfer protein sec14p |
View | Download | 0.258 | d.82.2 | Frataxin-like |
View | Download | 0.258 | a.24.15 | FAD-dependent thiol oxidase |
View | Download | 0.256 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
View | Download | 0.253 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
View | Download | 0.252 | a.8.3 | Families 57/38 glycoside transferase middle domain |
View | Download | 0.245 | a.50.1 | Anaphylotoxins (complement system) |
View | Download | 0.242 | a.126.1 | Serum albumin-like |
View | Download | 0.239 | a.64.1 | Saposin |
View | Download | 0.239 | a.26.1 | 4-helical cytokines |
View | Download | 0.233 | a.1.1 | Globin-like |
View | Download | 0.231 | a.17.1 | p8-MTCP1 |
View | Download | 0.231 | a.118.8 | TPR-like |
View | Download | 0.230 | d.226.1 | GIY-YIG endonuclease |
View | Download | 0.229 | a.5.6 | Hypothetical protein MTH1615 |
View | Download | 0.227 | a.4.1 | Homeodomain-like |
View | Download | 0.221 | a.74.1 | Cyclin-like |
View | Download | 0.219 | a.1.1 | Globin-like |
View | Download | 0.218 | a.39.1 | EF-hand |
View | Download | 0.218 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
View | Download | 0.217 | a.39.1 | EF-hand |
View | Download | 0.216 | a.22.1 | Histone-fold |
View | Download | 0.215 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
View | Download | 0.211 | a.24.3 | Cytochromes |
View | Download | 0.209 | a.26.1 | 4-helical cytokines |
View | Download | 0.209 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
View | Download | 0.209 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
View | Download | 0.208 | a.24.17 | Group V grass pollen allergen |
View | Download | 0.204 | a.74.1 | Cyclin-like |
View | Download | 0.201 | a.47.2 | t-snare proteins |
Region A: Residues: [86-421] |
1 11 21 31 41 51 | | | | | | 1 DLDFDLRSLL HYLRSRQLEQ GIEPGDSGIA FKNLTAVGVD ASAAYGPSVE EMFRNIASIP 60 61 AHLISKFTKK SDVPLRNIIQ NCTGVVESGE MLFVVGRPGA GCSTFLKCLS GETSELVDVQ 120 121 GEFSYDGLDQ SEMMSKYKGY VIYCPELDFH FPKITVKETI DFALKCKTPR VRIDKMTRKQ 180 181 YVDNIRDMWC TVFGLRHTYA TKVGNDFVRG VSGGERKRVS LVEAQAMNAS IYSWDNATRG 240 241 LDASTALEFA QAIRTATNMV NNSAIVAIYQ AGENIYELFD KTTVLYNGRQ IYFGPADKAV 300 301 GYFQRMGWVK PNRMTSAEFL TSVTVDFENR TLDIKP |
Detection Method: | ![]() |
Confidence: | 122.38764 |
Match: | 1jj7A_ |
Description: | Peptide transporter Tap1, C-terminal ABC domain |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [422-838] |
1 11 21 31 41 51 | | | | | | 1 GYEDKVPKSS SEFEEYWLNS EDYQELLRTY DDYQSRHPVN ETRDRLDVAK KQRLQQGQRE 60 61 NSQYVVNYWT QVYYCMIRGF QRVKGDSTYT KVYLSSFLIK ALIIGSMFHK IDDKSQSTTA 120 121 GAYSRGGMLF YVLLFASVTS LAEIGNSFSS RPVIVKHKSY SMYHLSAESL QEIITEFPTK 180 181 FVAIVILCLI TYWIPFMKYE AGAFFQYILY LLTVQQCTSF IFKFVATMSK SGVDAHAVGG 240 241 LWVLMLCVYA GFVLPIGEMH HWIRWLHFIN PLTYAFESLV STEFHHREML CSALVPSGPG 300 301 YEGISIANQV CDAAGAVKGN LYVSGDSYIL HQYHFAYKHA WRNWGVNIVW TFGYIVFNVI 360 361 LSEYLKPVEG GGDLLLYKRG HMPELGTENA DARTASREEM MEALNGPNVD LEKVIAE |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [839-866] |
1 11 21 31 41 51 | | | | | | 1 KDVFTWNHLD YTIPYDGATR KLLSDVFG |
Region B: Residues: [888-916] |
1 11 21 31 41 51 | | | | | | 1 LNVLAQRINM GVITGDMLVN AKPLPASFN |
Detection Method: | ![]() |
Confidence: | 156.154902 |
Match: | 1mt0A_ |
Description: | Haemolysin B ATP-binding protein |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
lipid transporter activity | 7.47642599298853 | bayes_pls_golite062009 |
lipopolysaccharide transmembrane transporter activity | 5.90177503313326 | bayes_pls_golite062009 |
lipopolysaccharide-transporting ATPase activity | 5.90177503313326 | bayes_pls_golite062009 |
ATPase activity, coupled to transmembrane movement of substances | 5.57844095962502 | bayes_pls_golite062009 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 5.57813579764186 | bayes_pls_golite062009 |
ATPase activity, coupled to movement of substances | 5.57813579764186 | bayes_pls_golite062009 |
P-P-bond-hydrolysis-driven transmembrane transporter activity | 5.5689620139321 | bayes_pls_golite062009 |
primary active transmembrane transporter activity | 5.55992639965745 | bayes_pls_golite062009 |
active transmembrane transporter activity | 5.50005167063544 | bayes_pls_golite062009 |
polysaccharide transmembrane transporter activity | 5.26442752745523 | bayes_pls_golite062009 |
ATPase activity, coupled | 4.98276715440477 | bayes_pls_golite062009 |
ATPase activity | 4.69795387297193 | bayes_pls_golite062009 |
nucleoside-triphosphatase activity | 4.45923622153365 | bayes_pls_golite062009 |
sterol transporter activity | 4.45355165759136 | bayes_pls_golite062009 |
pyrophosphatase activity | 4.39781350157199 | bayes_pls_golite062009 |
hydrolase activity, acting on acid anhydrides | 4.38133275795019 | bayes_pls_golite062009 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 4.38085303582726 | bayes_pls_golite062009 |
transporter activity | 3.71239480053329 | bayes_pls_golite062009 |
hydrogen ion transporting ATP synthase activity, rotational mechanism | 3.57926427233638 | bayes_pls_golite062009 |
ion transmembrane transporter activity | 3.35436118751376 | bayes_pls_golite062009 |
hydrolase activity | 3.14498892233323 | bayes_pls_golite062009 |
transmembrane transporter activity | 3.13960906549884 | bayes_pls_golite062009 |
substrate-specific transporter activity | 3.1318898376276 | bayes_pls_golite062009 |
cation transmembrane transporter activity | 3.08390071341252 | bayes_pls_golite062009 |
iron ion transmembrane transporter activity | 3.05511942104215 | bayes_pls_golite062009 |
ATP binding | 3.01346604299372 | bayes_pls_golite062009 |
substrate-specific transmembrane transporter activity | 3.00745742755195 | bayes_pls_golite062009 |
drug transmembrane transporter activity | 2.97119034312001 | bayes_pls_golite062009 |
adenyl ribonucleotide binding | 2.96271391116269 | bayes_pls_golite062009 |
adenyl nucleotide binding | 2.91131545957759 | bayes_pls_golite062009 |
branched-chain aliphatic amino acid transmembrane transporter activity | 2.88795687640992 | bayes_pls_golite062009 |
metal ion transmembrane transporter activity | 2.88476360771975 | bayes_pls_golite062009 |
cholesterol transporter activity | 2.72457626066894 | bayes_pls_golite062009 |
purine ribonucleotide binding | 2.70262534541085 | bayes_pls_golite062009 |
ribonucleotide binding | 2.70178191749524 | bayes_pls_golite062009 |
amine-transporting ATPase activity | 2.69529191205818 | bayes_pls_golite062009 |
organic acid transmembrane transporter activity | 2.67957846350199 | bayes_pls_golite062009 |
carboxylic acid transmembrane transporter activity | 2.67815672695824 | bayes_pls_golite062009 |
purine nucleotide binding | 2.6583477492092 | bayes_pls_golite062009 |
nucleotide binding | 2.62374702628143 | bayes_pls_golite062009 |
hydrogen ion transmembrane transporter activity | 2.61311581579476 | bayes_pls_golite062009 |
inorganic cation transmembrane transporter activity | 2.40292717311506 | bayes_pls_golite062009 |
amine transmembrane transporter activity | 2.29486577878686 | bayes_pls_golite062009 |
2.20174656498665 | bayes_pls_golite062009 | |
eye pigment precursor transporter activity | 2.19742277986318 | bayes_pls_golite062009 |
apolipoprotein A-I binding | 2.15656963765495 | bayes_pls_golite062009 |
apolipoprotein receptor activity | 2.15656963765495 | bayes_pls_golite062009 |
syntaxin-13 binding | 2.15656963765495 | bayes_pls_golite062009 |
apolipoprotein A-I receptor activity | 2.15656963765495 | bayes_pls_golite062009 |
anion transmembrane-transporting ATPase activity | 2.12727614888121 | bayes_pls_golite062009 |
proton-transporting ATPase activity, rotational mechanism | 1.95782378818812 | bayes_pls_golite062009 |
inorganic anion transmembrane transporter activity | 1.88153949603611 | bayes_pls_golite062009 |
transition metal ion transmembrane transporter activity | 1.82177108193332 | bayes_pls_golite062009 |
fluconazole transporter activity | 1.75428613304237 | bayes_pls_golite062009 |
azole transporter activity | 1.75428613304237 | bayes_pls_golite062009 |
binding | 1.64266915208623 | bayes_pls_golite062009 |
amino acid transmembrane transporter activity | 1.59627719545436 | bayes_pls_golite062009 |
monovalent inorganic cation transmembrane transporter activity | 1.58971273330352 | bayes_pls_golite062009 |
peptide-transporting ATPase activity | 1.37783759788533 | bayes_pls_golite062009 |
cation channel activity | 1.33585529285301 | bayes_pls_golite062009 |
signal recognition particle binding | 1.23869719200594 | bayes_pls_golite062009 |
ATPase activity, coupled to transmembrane movement of ions | 1.23799860254751 | bayes_pls_golite062009 |
peptide transporter activity | 1.19353064661766 | bayes_pls_golite062009 |
potassium channel activity | 1.17288958041707 | bayes_pls_golite062009 |
GTPase activity | 1.16964908174651 | bayes_pls_golite062009 |
voltage-gated cation channel activity | 1.00384984515681 | bayes_pls_golite062009 |
nucleic acid binding | 0.896078342024449 | bayes_pls_golite062009 |
voltage-gated ion channel activity | 0.889208591820696 | bayes_pls_golite062009 |
voltage-gated channel activity | 0.871525745291603 | bayes_pls_golite062009 |
0.869999622006359 | bayes_pls_golite062009 | |
ion channel activity | 0.848261056209476 | bayes_pls_golite062009 |
passive transmembrane transporter activity | 0.806331380134838 | bayes_pls_golite062009 |
channel activity | 0.806331380134838 | bayes_pls_golite062009 |
substrate-specific channel activity | 0.799997700906738 | bayes_pls_golite062009 |
di-, tri-valent inorganic cation transmembrane transporter activity | 0.767424210804186 | bayes_pls_golite062009 |
phospholipid transporter activity | 0.755445322666929 | bayes_pls_golite062009 |
motor activity | 0.677658554107 | bayes_pls_golite062009 |
gated channel activity | 0.650050847753837 | bayes_pls_golite062009 |
DNA-dependent ATPase activity | 0.62832939629645 | bayes_pls_golite062009 |
anion transmembrane transporter activity | 0.43332053110728 | bayes_pls_golite062009 |
catalytic activity | 0.368034275052766 | bayes_pls_golite062009 |
DNA binding | 0.361518668029935 | bayes_pls_golite062009 |
canalicular bile acid transmembrane transporter activity | 0.301752323171649 | bayes_pls_golite062009 |
neutral amino acid transmembrane transporter activity | 0.227570438294493 | bayes_pls_golite062009 |
G-protein coupled receptor activity | 0.169034229773346 | bayes_pls_golite062009 |
amino acid-transporting ATPase activity | 0.147644650870465 | bayes_pls_golite062009 |
signal transducer activity | 0.144122328222529 | bayes_pls_golite062009 |
molecular transducer activity | 0.144122328222529 | bayes_pls_golite062009 |
transcription regulator activity | 0.133605084599819 | bayes_pls_golite062009 |
microtubule motor activity | 0.11674780318211 | bayes_pls_golite062009 |
protein transporter activity | 0.104820191623932 | bayes_pls_golite062009 |
protein binding | 0.071010918255742 | bayes_pls_golite062009 |
cation-transporting ATPase activity | 0.0536898657672154 | bayes_pls_golite062009 |
structure-specific DNA binding | 0.050232896280066 | bayes_pls_golite062009 |
ribonucleoprotein binding | 0.0181245554613096 | bayes_pls_golite062009 |
Region A: Residues: [867-887] |
1 11 21 31 41 51 | | | | | | 1 YVKPGKMTAL MGESGAGKTT L |
Region B: Residues: [917-1091] |
1 11 21 31 41 51 | | | | | | 1 RSCGYVAQAD NHMAELSVRE SLRFAAELRQ QSSVPLEEKY EYVEKIITLL GMQNYAEALV 60 61 GKTGRGLNVE QRKKLSIGVE LVAKPSLLLF LDEPTSGLDS QSAWSIVQFM RALADSGQSI 120 121 LCTIHQPSAT LFEQFDRLLL LKKGGKMVYF GDIGPNSETL LKYFERQSGM KCGVS |
Detection Method: | ![]() |
Confidence: | 156.154902 |
Match: | 1mt0A_ |
Description: | Haemolysin B ATP-binding protein |
Matching Structure (courtesy of the PDB):![]() |
Region A: Residues: [1092-1389] |
1 11 21 31 41 51 | | | | | | 1 ENPAEYILNC IGAGATASVN SDWHDLWLAS PECAAARAEV EELHRTLPGR AVNDDPELAT 60 61 RFAASYMTQI KCVLRRTALQ FWRSPVYIRA KFFECVACAL FVGLSYVGVN HSVGGAIEAF 120 121 SSIFMLLLIA LAMINQLHVF AYDSRELYEV REAASNTFHW SVLLLCHAAV ENFWSTLCQF 180 181 MCFICYYWPA QFSGRASHAG FFFFFYVLIF PLYFVTYGLW ILYMSPDVPS ASMINSNLFA 240 241 AMLLFCGILQ PREKMPAFWR RLMYNVSPFT YVVQALVTPL VHNKKVVCNP HEYNIMDP |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [1390-1511] |
1 11 21 31 41 51 | | | | | | 1 PSGKTCGEFL STYMDNNTGY LVNPTATENC QYCPYTVQDQ VVAKYNVKWD HRWRNFGFMW 60 61 AYICFNIAAM LICYYVVRVK VWSLKSVLNF KKWFNGPRKE RHEKDTNIFQ TVPGDENKIT 120 121 KK |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
SCOP Match |
SCOP Description | ||
View | Download | 0.503 | a.22.1 | Histone-fold |
View | Download | 0.543 | a.7.1 | Spectrin repeat |
View | Download | 0.421 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
View | Download | 0.545 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
View | Download | 0.545 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
View | Download | 0.543 | a.7.1 | Spectrin repeat |
View | Download | 0.503 | a.22.1 | Histone-fold |
View | Download | 0.421 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
View | Download | 0.376 | a.22.1 | Histone-fold |
View | Download | 0.376 | a.22.1 | Histone-fold |
View | Download | 0.353 | b.40.4 | Nucleic acid-binding proteins |
View | Download | 0.320 | a.47.2 | t-snare proteins |
View | Download | 0.303 | a.4.12 | TrpR-like |
View | Download | 0.277 | i.11.1 | Computational models partly based on NMR data |
View | Download | 0.272 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
View | Download | 0.266 | c.55.1 | Actin-like ATPase domain |
View | Download | 0.265 | a.7.8 | GAT domain |
View | Download | 0.260 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
View | Download | 0.250 | a.74.1 | Cyclin-like |
View | Download | 0.209 | a.23.2 | Diol dehydratase, gamma subunit |
View | Download | 0.204 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |