| Protein: | PDR18 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1333 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR18.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [2..1333] | [163..1482] |
|
|
0.0 | [3..1332] | [130..1457] |
|
|
0.0 | [1..1332] | [132..1457] |
|
|
0.0 | [1..1333] | [107..1426] |
|
|
0.0 | [3..1332] | [119..1468] |
|
|
0.0 | [2..1333] | [71..1388] |
|
|
0.0 | [1..1332] | [137..1493] |
|
Region A: Residues: [1-308] |
1 11 21 31 41 51
| | | | | |
1 MECVSVEGLD SSFLEGQTFG DILCLPWTII KGIRERKNRN KMKIILKNVS LLAKSGEMVL 60
61 VLGRPGAGCT SFLKSAAGET SQFAGGVTTG HISYDGIPQK EMMQHYKPDV IYNGEQDVHF 120
121 PHLTVKQTLD FAISCKMPAK RVNNVTKEEY ITANREFYAK IFGLTHTFDT KVGNDFISGV 180
181 SGGERKRVSI AEALAAKGSI YCWDNATRGL DSSTALEFAR AIRTMTNLLG TTALVTVYQA 240
241 SENIYETFDK VTVLYAGRQI FCGKTTEAKD YFENMGYLCP PRQSTAEYLT AITDPNGLHE 300
301 IKPGFEYQ
|
| Detection Method: |  |
| Confidence: | 124.045757 |
| Match: | 1jj7A_ |
| Description: | Peptide transporter Tap1, C-terminal ABC domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [309-367] |
1 11 21 31 41 51
| | | | | |
1 VPHTADEFEK YWLDSPEYAR LKGEIQKYKH EVNTEWTKKT YNESMAQEKS KGTRKKSYY
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.776 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.776 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.635 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.813 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.581 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.534 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) |
| View | Download | 0.510 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.497 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.480 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.471 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.460 | a.5.2 | UBA-like |
| View | Download | 0.455 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.426 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.423 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.404 | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.402 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.387 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.382 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.375 | a.5.2 | UBA-like |
| View | Download | 0.361 | a.5.2 | UBA-like |
| View | Download | 0.360 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.353 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.342 | a.46.1 | Methionine synthase domain |
| View | Download | 0.334 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.332 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.324 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.320 | c.95.1 | Thiolase-like |
| View | Download | 0.319 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.313 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.304 | a.17.1 | p8-MTCP1 |
| View | Download | 0.292 | a.2.7 | tRNA-binding arm |
| View | Download | 0.285 | a.39.1 | EF-hand |
| View | Download | 0.235 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.230 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.228 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.227 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.226 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.223 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.222 | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.219 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.203 | a.39.1 | EF-hand |
| View | Download | 0.201 | a.4.7 | Ribosomal protein L11, C-terminal domain |
| View | Download | 0.201 | a.60.2 | RuvA domain 2-like |
|
Region A: Residues: [368-481] |
1 11 21 31 41 51
| | | | | |
1 TVSYWEQIRL CTIRGFLRIY GDKSYTVINT CAAIAQAFIT GSLFYQAPSS TLGAFSRSGV 60
61 LFFSLLYYSL MGLANISFEH RPILQKHKVY SLYHPSAEAL ASTISSFPFR MIGL
|
|
Region B: Residues: [523-710] |
1 11 21 31 41 51
| | | | | |
1 SSLCDTLSQA NSIAGVVMLS IAMYSTYMIQ LPSMHPWFKW ISYILPIRYA FESMLNAEFH 60
61 GRHMDCGGTL VPSGPGFENI LPENQVCAFV GSRPGQSWVL GDDYLRAQYQ YEYKNTWRNF 120
121 GIMWCFLIGY IVLRAVFTEY KSPVKSGGDA LVVKKGTKNA IQRSWSSKND EENLNASIAT 180
181 QDMKEIAS
|
| Detection Method: | |
| Confidence: | 169.616428 |
| Match: | 1jsqA_ |
| Description: | MsbA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| lipid transporter activity | 7.47642599298853 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 5.57844095962502 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 5.57813579764186 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 5.57813579764186 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 5.5689620139321 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 5.55992639965745 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 5.50005167063544 | bayes_pls_golite062009 |
| ATPase activity, coupled | 4.98276715440477 | bayes_pls_golite062009 |
| ATPase activity | 4.69795387297193 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 4.45923622153365 | bayes_pls_golite062009 |
| sterol transporter activity | 4.45355165759136 | bayes_pls_golite062009 |
| pyrophosphatase activity | 4.39781350157199 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 4.38133275795019 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 4.38085303582726 | bayes_pls_golite062009 |
| transporter activity | 3.71239480053329 | bayes_pls_golite062009 |
| hydrolase activity | 3.67426835966263 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 3.57926427233638 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 3.35436118751376 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.13960906549884 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.1318898376276 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 3.08390071341252 | bayes_pls_golite062009 |
| iron ion transmembrane transporter activity | 3.05511942104215 | bayes_pls_golite062009 |
| ATP binding | 3.01346604299372 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 3.00745742755195 | bayes_pls_golite062009 |
| drug transmembrane transporter activity | 2.97119034312001 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 2.96271391116269 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 2.91131545957759 | bayes_pls_golite062009 |
| branched-chain aliphatic amino acid transmembrane transporter activity | 2.88795687640992 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 2.88476360771975 | bayes_pls_golite062009 |
| cholesterol transporter activity | 2.72457626066894 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 2.70262534541085 | bayes_pls_golite062009 |
| ribonucleotide binding | 2.70178191749524 | bayes_pls_golite062009 |
| amine-transporting ATPase activity | 2.69529191205818 | bayes_pls_golite062009 |
| organic acid transmembrane transporter activity | 2.67957846350199 | bayes_pls_golite062009 |
| carboxylic acid transmembrane transporter activity | 2.67815672695824 | bayes_pls_golite062009 |
| purine nucleotide binding | 2.6583477492092 | bayes_pls_golite062009 |
| nucleotide binding | 2.62374702628143 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 2.61311581579476 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.40292717311506 | bayes_pls_golite062009 |
| amine transmembrane transporter activity | 2.29486577878686 | bayes_pls_golite062009 |
| 2.20174656498665 | bayes_pls_golite062009 | |
| apolipoprotein receptor activity | 2.15656963765495 | bayes_pls_golite062009 |
| syntaxin-13 binding | 2.15656963765495 | bayes_pls_golite062009 |
| apolipoprotein A-I binding | 2.15656963765495 | bayes_pls_golite062009 |
| apolipoprotein A-I receptor activity | 2.15656963765495 | bayes_pls_golite062009 |
| anion transmembrane-transporting ATPase activity | 2.12727614888121 | bayes_pls_golite062009 |
| proton-transporting ATPase activity, rotational mechanism | 1.95782378818812 | bayes_pls_golite062009 |
| inorganic anion transmembrane transporter activity | 1.88153949603611 | bayes_pls_golite062009 |
| binding | 1.84115074893083 | bayes_pls_golite062009 |
| transition metal ion transmembrane transporter activity | 1.82177108193332 | bayes_pls_golite062009 |
| azole transporter activity | 1.75428613304237 | bayes_pls_golite062009 |
| fluconazole transporter activity | 1.75428613304237 | bayes_pls_golite062009 |
| protein transporter activity | 1.71214667007262 | bayes_pls_golite062009 |
| nucleic acid binding | 1.62884148289979 | bayes_pls_golite062009 |
| amino acid transmembrane transporter activity | 1.59627719545436 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 1.58971273330352 | bayes_pls_golite062009 |
| DNA binding | 1.53176391519962 | bayes_pls_golite062009 |
| transcription regulator activity | 1.49517431175162 | bayes_pls_golite062009 |
| signal recognition particle binding | 1.46975774710831 | bayes_pls_golite062009 |
| peptide-transporting ATPase activity | 1.37783759788533 | bayes_pls_golite062009 |
| cation channel activity | 1.33585529285301 | bayes_pls_golite062009 |
| sterol-transporting ATPase activity | 1.30536878174919 | bayes_pls_golite062009 |
| glycoprotein transporter activity | 1.30536878174919 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of ions | 1.23799860254751 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| peptide transporter activity | 1.19353064661766 | bayes_pls_golite062009 |
| potassium channel activity | 1.17288958041707 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 1.00384984515681 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.889208591820696 | bayes_pls_golite062009 |
| motor activity | 0.87979065815418 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.871525745291603 | bayes_pls_golite062009 |
| 0.869999622006359 | bayes_pls_golite062009 | |
| ion channel activity | 0.848261056209476 | bayes_pls_golite062009 |
| GTPase activity | 0.83849854735032 | bayes_pls_golite062009 |
| channel activity | 0.806331380134838 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.806331380134838 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.799997700906738 | bayes_pls_golite062009 |
| di-, tri-valent inorganic cation transmembrane transporter activity | 0.767424210804186 | bayes_pls_golite062009 |
| phospholipid transporter activity | 0.755445322666929 | bayes_pls_golite062009 |
| gated channel activity | 0.650050847753837 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.640772201693186 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.63468044350616 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.62832939629645 | bayes_pls_golite062009 |
| GTP binding | 0.621689261700018 | bayes_pls_golite062009 |
| ribonucleoprotein binding | 0.53788302029845 | bayes_pls_golite062009 |
| anion transmembrane transporter activity | 0.43332053110728 | bayes_pls_golite062009 |
| catalytic activity | 0.368034275052766 | bayes_pls_golite062009 |
| transcription factor activity | 0.344643343870781 | bayes_pls_golite062009 |
| canalicular bile acid transmembrane transporter activity | 0.301752323171649 | bayes_pls_golite062009 |
| signal transducer activity | 0.286367085584159 | bayes_pls_golite062009 |
| molecular transducer activity | 0.286367085584159 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 0.169034229773346 | bayes_pls_golite062009 |
| amino acid-transporting ATPase activity | 0.147644650870465 | bayes_pls_golite062009 |
| microtubule motor activity | 0.11674780318211 | bayes_pls_golite062009 |
| cation-transporting ATPase activity | 0.0536898657672154 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.050232896280066 | bayes_pls_golite062009 |
| transcription activator activity | 0.0291047953833683 | bayes_pls_golite062009 |
|
Region A: Residues: [482-522] |
1 11 21 31 41 51
| | | | | |
1 TFFIIILYFL AGLHRSAGAF FTMYLLLTMC SEAITSLFQM V
|
|
Region B: Residues: [711-977] |
1 11 21 31 41 51
| | | | | |
1 SNDDSTSADF EGLESTGVFI WKNVSFTIPH SSGQRKLLDS VSGYCVPGTL TALIGESGAG 60
61 KTTLLNTLAQ RNVGTITGDM LVDGLPMDAS FKRRTGYVQQ QDLHVAELTV KESLQFSARM 120
121 RRPQSIPDAE KMEYVEKIIS ILEMQEFSEA LVGEIGYGLN VEQRKKLSIG VELVGKPDLL 180
181 LFLDEPTSGL DSQSAWAVVK MLKRLALAGQ SILCTIHQPS ATLFEQFDRL LLLGKGGQTI 240
241 YFGEIGKNSS SVIKYFEKNG ARKCQQN
|
| Detection Method: | |
| Confidence: | 169.616428 |
| Match: | 1jsqA_ |
| Description: | MsbA |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [978-1273] |
1 11 21 31 41 51
| | | | | |
1 ENPAEYILEA IGAGATASVQ QNWPDIWQKS HEYANINEKI NDMIKDLSST TLHKTATRAS 60
61 KYATSYSYQF HHVLKRSSLT FWRNLNYIMA KMMLLMISGL FIGFTFFHVG VNAIGLQNSL 120
121 FACFMAIVIS APATNQIQER ATVAKELYEV RESKSNMFHW SLLLITHYLN ELPYHLLFST 180
181 IFFVSSYFPL GVFTEASRSS VFYLNYAILF QLYYIGLALM ILYMSPNLQS ANVIVGFILS 240
241 FLLSFCGAVQ PASLMPGFWT FMWKLSPYTY FLQNLVGLLM HDKPVRCSKK ELSLFN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1274-1333] |
1 11 21 31 41 51
| | | | | |
1 PPVGQTCGEF TKPFFEFGTG YIANPDATAD CAYCQYKVGD EYLARINASF SYLWRNFGFI 60
61
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.352 | g.7.1 | Snake toxin-like |
| View | Download | 0.500 | d.58.5 | GlnB-like |
| View | Download | 0.436 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.343 | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.332 | d.58.49 | YajQ-like |
| View | Download | 0.323 | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.263 | b.107.1 | Urease metallochaperone UreE, N-terminal domain |
| View | Download | 0.262 | d.10.1 | DNA-binding domain |
| View | Download | 0.260 | d.9.2 | Description not found. |
| View | Download | 0.243 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.228 | d.58.17 | Metal-binding domain |
| View | Download | 0.226 | g.7.1 | Snake toxin-like |
| View | Download | 0.219 | d.58.40 | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| View | Download | 0.217 | g.10.1 | Hairpin loop containing domain-like |
| View | Download | 0.203 | d.58.8 | Viral DNA-binding domain |
