| Protein: | STE7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 515 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..515] | [1..515] |
|
|
0.0 | [27..485] | [96..522] |
|
|
0.0 | [27..485] | [105..539] |
|
|
0.0 | [27..485] | [100..538] |
|
|
0.0 | [27..485] | [105..539] |
|
|
0.0 | [10..514] | [76..554] |
|
|
0.0 | [27..485] | [105..540] |
|
Region A: Residues: [1-131] |
1 11 21 31 41 51
| | | | | |
1 MFQRKTLQRR NLKGLNLNLH PDVGNNGQLQ EKTETHQGQS RIEGHVMSNI NAIQNNSNLF 60
61 LRRGIKKKLT LDAFGDDQAI SKPNTVVIQQ PQNEPVLVLS SLSQSPCVSS SSSLSTPCII 120
121 DAYSNNFGLS P
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.423 | c.47.1 | Thioredoxin-like |
| View | Download | 0.271 | b.55.1 | PH domain-like |
| View | Download | 0.382 | d.17.4 | NTF2-like |
| View | Download | 0.400 | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.423 | c.47.1 | Thioredoxin-like |
| View | Download | 0.400 | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.382 | d.17.4 | NTF2-like |
| View | Download | 0.279 | c.47.1 | Thioredoxin-like |
| View | Download | 0.279 | c.47.1 | Thioredoxin-like |
| View | Download | 0.271 | b.55.1 | PH domain-like |
| View | Download | 0.226 | a.35.1 | lambda repressor-like DNA-binding domains |
|
Region A: Residues: [132-273] |
1 11 21 31 41 51
| | | | | |
1 SSTNSTPSTI QGLSNIATPV ENEHSISLPP LEESLSPAAA DLKDTLSGTS NGNYIQLQDL 60
61 VQLGKIGAGN SGTVVKALHV PDSKIVAKKT IPVEQNNSTI INQLVRELSI VKNVKPHENI 120
121 ITFYGAYYNQ HINNEIIILM EY
|
| Detection Method: | |
| Confidence: | 379.9794 |
| Match: | 1f3mC_ |
| Description: | pak1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 2.58388574483759 | bayes_pls_golite062009 |
| type II transforming growth factor beta receptor binding | 2.55651678344227 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 2.41610417530517 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.25301480460598 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.188721764136 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.12618184009486 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| MAP kinase 2 activity | 1.93464174962664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| telethonin binding | 1.75733591474207 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
| PTB domain binding | 1.69692410125184 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.65350201428136 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 1.60259443694567 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.28428643482914 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 1.21636393741109 | bayes_pls_golite062009 |
| structural constituent of muscle | 1.19908793854422 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 1.16995153203536 | bayes_pls_golite062009 |
| transcription repressor activity | 1.14496167267281 | bayes_pls_golite062009 |
| histone kinase activity (H3-S10 specific) | 1.14432210832726 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.893952447158008 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.877087652539674 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 0.870666814073948 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| cation channel activity | 0.752655339263581 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 0.537170519944039 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.451090007290896 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.318153468064373 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.26579358730346 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 0.01826424351081 | bayes_pls_golite062009 |
| nitric-oxide synthase regulator activity | 0.00407218246327123 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [274-515] |
1 11 21 31 41 51
| | | | | |
1 SDCGSLDKIL SVYKRFVQRG TVSSKKTWFN ELTISKIAYG VLNGLDHLYR QYKIIHRDIK 60
61 PSNVLINSKG QIKLCDFGVS KKLINSIADT FVGTSTYMSP ERIQGNVYSI KGDVWSLGLM 120
121 IIELVTGEFP LGGHNDTPDG ILDLLQRIVN EPSPRLPKDR IYSKEMTDFV NRCCIKNERE 180
181 RSSIHELLHH DLIMKYVSPS KDDKFRHWCR KIKSKIKEDK RIKREALDRA KLEKKQSERS 240
241 TH
|
| Detection Method: | |
| Confidence: | 379.9794 |
| Match: | 1f3mC_ |
| Description: | pak1 |
| Matching Structure (courtesy of the PDB): |
|
